Podcast #395:  Aspirin for everyone!

Podcast #395: Aspirin for everyone!

Author: Aaron Lessen, MD

Educational Pearls:

  • In patients without indications for aspirin, three recent studies looked at prevention of several end points in the elderly
  • These showed no benefit in preventing cardiovascular events (stroke, MI, hear failure), disability, or death in elderly
  • These studies also demonstrated higher mortality and increased bleeding risk in patients who were taking aspirin without clear indications

Editor's note: the increased all cause mortality is intriguing - but attributed to an increase in cancer mortality. Unclear why but will be important to see if this trend is seen in other studies.

References:

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on Disability-free Survival in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1499-1508. doi: 10.1056/NEJMoa1800722. Epub 2018 Sep 16. PubMed PMID: 30221596.

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1509-1518. doi: 10.1056/NEJMoa1805819. Epub 2018 Sep 16. PubMed PMID: 30221597.

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1519-1528. doi: 10.1056/NEJMoa1803955. Epub 2018 Sep 16. PubMed PMID: 30221595.

Summary by Travis Barlock, MS4 | Edited by Erik Verzemnieks, MD



Jaksot(1148)

Podcast 540:   Zyprexa

Podcast 540: Zyprexa

Contributor:  Don Stader, MD Educational Pearls: Olanzapine (Zyprexa) is an atypical antipsychotic that can be used in a similar fashion to haloperidol for pain and nausea, including that with abdomi...

11 Helmi 20202min

Podcast 539:  Coricidin Abuse

Podcast 539: Coricidin Abuse

Contributor:  Rachel Beham, PharmD Educational Pearls: Coricidin HBP Cough & Cold (dextromethorphan and chlorpheniramine) is one of the more commonly abused over-the-counter medications Dextromethorp...

10 Helmi 20203min

Podcast 538:  Low Maintenance Boxer's Fracture

Podcast 538: Low Maintenance Boxer's Fracture

Contributor: Jared Scott, MD Educational Pearls: A distal 5th metacarpal neck fracture is often referred to as a "boxer's fracture" and a common fracture encountered in the emergency department Splin...

4 Helmi 20202min

Podcast 537:  Thoughts on Cardiac Arrest

Podcast 537: Thoughts on Cardiac Arrest

Contributor:  Don Stader, MD Educational Pearls: High-quality compressions are an essential, and probably one of the most important, part of cardiac arrest  Actual evidence for drugs in cardiac arres...

3 Helmi 20205min

UnfilterED #4: Dr. Vivek Tayal

UnfilterED #4: Dr. Vivek Tayal

Dr. Vivek Tayal of Carolinas Medical Center, a pioneer of using ultrasound in the emergency department, reflects on his role in establishing ultrasound use in emergency medicine and much more! Ultra...

29 Tammi 202045min

Podcast 536:  Epistaxis 101

Podcast 536: Epistaxis 101

Contributor:  Dylan Luyten, MD Educational Pearls: Clear the nasal passages - have the patient, if stable, blow their nose to dislodge any clot that might be in the way Searching for the source of bl...

28 Tammi 20208min

Podcast 535: A Prescription for Falls

Podcast 535: A Prescription for Falls

Contributor: Aaron Lessen, MD Educational Pearls: Emergency department evaluation of falls, particularly in the elderly, should include an assessment of risk factors Common causes of falls in th...

28 Tammi 20202min

Mental Health Monthly #1: Decision Making Capacity

Mental Health Monthly #1: Decision Making Capacity

In the first episode of this new series, the complexities of decision making capacity are discussed. References and Further Reading: [1] Appelbaum, P. S. (2007). Assessment of patients' competence to...

22 Tammi 202010min

Suosittua kategoriassa Tiede

rss-mita-tulisi-tietaa
utelias-mieli
rss-poliisin-mieli
tiedekulma-podcast
docemilia
rss-duodecim-lehti
filocast-filosofian-perusteet
rss-ylistys-elaimille
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita
mielipaivakirja
radio-antro
rss-tervetuloa-tervemenoa
rss-tervetta-skeptisyytta
rss-sosiopodi