#458: The Psychedelic News Hour: New Breakthroughs, Compound Comparisons and Warnings (Psilocybin/LSD/Ayahuasca/N,N-DMT/5-MeO-DMT), Treatment of Trauma, Scalable vs. Unscalable Approaches, Making Sense of “Bad” Trips, and Much More

#458: The Psychedelic News Hour: New Breakthroughs, Compound Comparisons and Warnings (Psilocybin/LSD/Ayahuasca/N,N-DMT/5-MeO-DMT), Treatment of Trauma, Scalable vs. Unscalable Approaches, Making Sense of “Bad” Trips, and Much More

Welcome to another episode of The Tim Ferriss Show, where it is normally my job to deconstruct world-class performers of various types, of all ilks.

In this special episode, the tables are turned. Instead of interviewing someone else, I am interviewed by two experts on several topics I’ve both studied and supported, including psychedelic-assisted psychotherapy and what it can do to heal trauma and—broadly speaking—possible futures for mental health. This audio was recorded on a new show, The Psychedelic News Hour, soon to be a podcast, and I’m in conversation with two people: David Rabin, MD, PhD, (@drdavidrabin), a board-certified psychiatrist and neuroscientist, executive director of The Board of Medicine, and co-founder of Apollo Neuroscience, and Molly Maloof, MD, (@drmolly.co), a physician, Stanford lecturer, and ketamine-assisted psychotherapist.

This episode was recorded on Clubhouse, an app still in private beta and defined by their tagline: “Clubhouse is a space for casual, drop-in audio conversations—with friends and other interesting people around the world.”

One final note: I recorded this on my phone, a necessity for using the app, so the audio quality isn’t studio quality, but it was polished as much as possible. Thank you for understanding, and thanks to everyone who joined and asked thoughtful questions.

This episode is brought to you by the book How to Lead by David Rubenstein. David Rubenstein is one of the visionary founders of The Carlyle Group and host of The David Rubenstein Show, where he speaks to leaders from every walk of life about who they are, how they define "success," and what it means to lead. Jeff Bezos, Richard Branson, Warren Buffet, Bill Gates, Ruth Bader Ginsburg, Phil Knight, Oprah — all of them and more — are featured in his new book, titled How to Lead. This comprehensive leadership playbook illustrates the principles and guiding philosophies of the world’s greatest game-changers. In its pages, you can discover the experts’ secrets to being effective and innovative leaders.

Past podcast guest Walter Isaacson had this to say: "Reading this invaluable trove of advice from the greatest leaders of our time is like sitting in an armchair and listening to the masters reveal their secrets.” Pick up a copy of How to Lead: Wisdom from the World’s Greatest CEOs, Founders, and Game Changers by David Rubinstein in hardcover, ebook, or audio anywhere books are sold.

***

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For show notes and past guests, please visit tim.blog/podcast.

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Past guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, and many more.

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Jaksot(860)

#840: Bill Gurley — Investing in The AI Era, 10 Days in China, and Important Life Lessons from Bob Dylan, Jerry Seinfeld, MrBeast, and More

#840: Bill Gurley — Investing in The AI Era, 10 Days in China, and Important Life Lessons from Bob Dylan, Jerry Seinfeld, MrBeast, and More

Bill Gurley (@bgurley) is a general partner at Benchmark, a leading venture capital firm in Silicon Valley. His new book is Runnin’ Down a Dream: How to Thrive in a Career You Actually Love.This episo...

17 Joulu 20252h 10min

#839: Dr. Fei-Fei Li, The Godmother of AI — Asking Audacious Questions, Civilizational Technology, and Finding Your North Star

#839: Dr. Fei-Fei Li, The Godmother of AI — Asking Audacious Questions, Civilizational Technology, and Finding Your North Star

Dr. Fei-Fei Li (@drfeifei) is the inaugural Sequoia Professor in the Computer Science Department at Stanford University, a founding co-director of Stanford’s Human-Centered AI Institute, and the co-fo...

9 Joulu 20251h 18min

#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello

#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello

Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)!This episode is brought to you by:Qlosi prescription eye drop used to treat age-related...

3 Joulu 20251h 51min

#837: How to Simplify Your Life in 2026 — New Tips from Derek Sivers, Seth Godin, and Martha Beck

#837: How to Simplify Your Life in 2026 — New Tips from Derek Sivers, Seth Godin, and Martha Beck

As we head into the new year, many of us feel like we’re drowning in invisible complexity. So I wanted to hit pause and ask a simple question: What are 1-3 decisions that could dramatically simplify m...

26 Marras 202532min

#836: The 4-Hour Workweek Principles — 13 Mistakes to Avoid, The Art of Mini-Retirements, and Navigating the Dizziness of Freedom

#836: The 4-Hour Workweek Principles — 13 Mistakes to Avoid, The Art of Mini-Retirements, and Navigating the Dizziness of Freedom

This time around, we have a bit of a different format, featuring the book that started it all for me, The 4-Hour Workweek. Readers and listeners often ask me what I would change or update, but an equa...

19 Marras 20251h 37min

#835: Ben Patrick (KneesOverToesGuy) — 20-Minute Workouts That Produce Wild Results, From Chronic Knee Pain to Dunking Basketballs, Lessons from Charles Poliquin, Bulletproofing the Lower Body, and More

#835: Ben Patrick (KneesOverToesGuy) — 20-Minute Workouts That Produce Wild Results, From Chronic Knee Pain to Dunking Basketballs, Lessons from Charles Poliquin, Bulletproofing the Lower Body, and More

Ben Patrick, better known as “Kneesovertoesguy” (@kneesovertoesguy), is the founder of Athletic Truth Group (ATG), an online and brick-and-mortar training system rooted in rehabilitative strength and ...

12 Marras 20251h 37min

#834: David Baszucki, Co-Founder of Roblox — The Path to 150M+ Daily Users, Critical Business Decisions, Ketogenic Therapy for Brain Health, Daily Routines, The Roblox Economy, and More

#834: David Baszucki, Co-Founder of Roblox — The Path to 150M+ Daily Users, Critical Business Decisions, Ketogenic Therapy for Brain Health, Daily Routines, The Roblox Economy, and More

David Baszucki is the founder and CEO of Roblox. TIME named Roblox one of the “100 Most Influential Companies,” and it has been recognized by Fast Company for innovation on their “Most Innovative Comp...

5 Marras 20251h 55min

#833: Jack Canfield — Selling 600+ Million Books, Success Principles, and How He Made The 4-Hour Workweek Happen

#833: Jack Canfield — Selling 600+ Million Books, Success Principles, and How He Made The 4-Hour Workweek Happen

Jack Canfield is the coauthor of more than two hundred books, including, The Success Principles™: How to Get from Where You Are to Where You Want to Be and the Chicken Soup for the Soul® series, which...

29 Loka 20251h 37min

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