About IBD11 Heinä 2022

IBD and Biomarkers: What You Need to Know With Andres Hurtado-Lorenzo, PhD

What if we knew which patients would have severe Crohn's disease or ulcerative colitis? And which wouldn't? How about if we could tell which drug would work best in which patient? Knowing these things would change how inflammatory bowel disease (IBD) is diagnosed and treated. Plus, more importantly: it would improve lives. Dr Andres Hurtado-Lorenzo, Vice President of Translational research and IBD Ventures at the Crohn's and Colitis Foundation explains biomarkers and how they may play into the future of how IBD is diagnosed, managed, and treated.

Resources:

Crohn's & Colitis Foundation:https://www.crohnscolitisfoundation.org/
IBD Plexus:https://www.crohnscolitisfoundation.org/research/current-research-initiatives/ibd-plexus/about
RISK Study:https://www.crohnscolitisfoundation.org/research/current-research-initiatives/pediatric-risk-stratification
IBD Ventures:https://www.crohnscolitisfoundation.org/research/grants-fellowships/entrepreneurial-investing/portfolio
Olink: https://www.olink.com
Foundation for the National Institutes of Health: https://www.fnih.org
Genedata: https://www.com
Glycominds: https://www.glycominds.com/blood-tests-1
PredictImmune:https://www.predictimmune.com/

Research:

Honig G, Heller C, Hurtado-Lorenzo A. Defining the Path Forward for Biomarkers to Address Unmet Needs in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2020;26(10):1451-1462. doi:10.1093/ibd/izaa210. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500521/pdf/izaa210.pdf
Honig G, Larkin PB, Heller C, Hurtado-Lorenzo A. Research-Based Product Innovation to Address Critical Unmet Needs of Patients with Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2021;27(Suppl 2):S1-S16. doi:10.1093/ibd/izab230. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922161/pdf/izab230.pdf
Kugathasan S, Denson LA, Walters TD, et al. Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study. Lancet. 2017;389(10080):1710-1718. doi:10.1016/S0140-6736(17)30317-3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719489/pdf/nihms923305.pdf
Biasci D, Lee JC, Noor NM, et al. A blood-based prognostic biomarker in IBD. Gut. 2019;68(8):1386-1395. doi:10.1136/gutjnl-2019-318343. https://www.predictimmune.com/wp-content/uploads/2020/09/Biasci-et-al-A-blood-based-prognostic-biomarker-in-IBD-Gut-2019.pdf
de Bruyn M, Ringold R, Martens E, et al. The Ulcerative Colitis Response Index for Detection of Mucosal Healing in Patients Treated With Anti-tumour Necrosis Factor. J Crohns Colitis. 2020;14(2):176-184. doi:10.1093/ecco-jcc/jjz125. https://doi.org/10.1093/ecco-jcc/jjz125

Find Amber J Tresca at:

AboutIBD.com: http://aboutibd.com/
Verywell: https://www.verywell.com/ibd-crohns-colitis-4014703
Facebook: https://www.facebook.com/aboutIBD
Twitter: https://twitter.com/aboutIBD
Pinterest: https://www.pinterest.com/aboutibd/
Instagram: https://www.instagram.com/about_IBD/

Credits:

Mix and sound design is by Mac Cooney: https://www.facebook.com/michaelandrewcooney
Theme music, IBD Dance Party, is from ©Cooney Studio: https://michaelandrewcooney.bandcamp.com/track/ibd-dance-party-single

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Why Flare-Ups Aren't Failure: The Truth About Chronic Illness Grief

Transcript and more information: https://bit.ly/AIBD211 Flare-ups in chronic illness can reopen feelings of grief. Clinical psychologist Dr Antonia Repollet shares her journey with Crohn's disease a...

22 Syys 33min

How to Eat Well When Chronic Fatigue Makes Cooking Impossible With Nicholas Kelly MS, RD

Cystic fibrosis (CF) is thought of as a lung disease, but it affects the entire body. Amber Tresca speaks with Nicholas Kelly, MS, RD—a registered dietitian, public speaker, and cystic fibrosis advoca...

15 Syys 26min

Why Your Symptoms Get Dismissed (and How to Be Heard) — With Morgan Check, NP

Pediatric GI Nurse Practitioner Morgan Check shares her journey living with Crohn's disease, navigating a diagnosis change, emergency surgery, and motherhood. She uncovers the challenges facing women ...

25 Elo 39min

The Truth About How IBD Affects Families With Adam and Brandon Sikes

Adam Sikes was diagnosed with ulcerative colitis at 18 and later with stage 1 colon cancer. Along with his son Brandon, Adam shares how his family supported him through decades of illness, surgery, an...

18 Elo 31min

Powerful Lessons: How Women Experience Life With IBD Featuring Alicia Aiello of Girls With Guts

Episode transcript and more information at: https://bit.ly/AIBD207 Alicia Aiello, president of Girls With Guts, shares her journey with IBD, which began in childhood. She discusses major surgeries, in...

11 Elo 49min

Hidden Ways IBD Affects You Over a Lifetime With Puja Khanna, MD

The truth about inflammatory bowel disease (IBD) is that it goes beyond the gut. In this first ever live recording of About IBD, Amber talks with Dr. Puja Khanna from Cedars-Sinai to explore the extra...

21 Heinä 41min

How to Navigate ER Visits and Avoid Fragmented Care With Dr Stephen Lupe

Emergency room visits are a source of stress and can lead to fragmented care. Amber speaks with psychologist Dr Stephen Lupe to learn why inflammatory bowel disease (IBD) patients avoid the ER, the re...

7 Heinä 35min

Brown Note: Helping People with IBD Find Hope and Support With Andrew Giffin

Amber Tresca talks with Andrew Giffin, a product manager in Toronto who was diagnosed with Crohn's disease at 19 after years of symptoms in high school. Andrew shares his experience navigating three m...

23 Kesä 36min