Role of pre-clinical experimentation in intensive care: from ethical to clinical practice
ESICM Talk23 Maalis 2022

Role of pre-clinical experimentation in intensive care: from ethical to clinical practice

Preclinical studies precede most clinical trials. They help identify criteria for evaluating human safety, including signs and symptoms that should be monitored closely during early clinical trials.

The importance of these preclinical studies in intensive care medicine starts from developing new surgical procedures, and hands-on training to new medical devices and prescription drugs.

To have more insights into preclinical research and real examples of translation of such research in clinical practice, we interviewed Dr Marcin Osuchowski, an expert in the field.

Help us review our educational podcasts! Complete this short survey here.

Speakers

Marcin OSUCHOWSKI. Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA; Deputy Editor-In-Chief of the ESICM ICMx Journal.

Denise BATTAGLINI. Consultant in intensive care at San Martino Policlinico Hospital, Genoa, Italy (IT). ESICM NEXT Committee Member.

Ahmed ZAHER. Oxford University Hospitals (UK). ESICM Next Committee member.

Jaksot(90)

Life after sepsis in adult and paediatric patients

Life after sepsis in adult and paediatric patients

Sepsis is a life-threatening acute organ dysfunction secondary to infection and affects more than 19 million people annually. In 2017, it was estimated that almost 49 million people were infected by s...

13 Syys 202325min

Severe meningoencephalitis in the ICU: results from the EURECA study

Severe meningoencephalitis in the ICU: results from the EURECA study

Central nervous system (CNS) infections significantly burden ICU physicians' daily clinical work. Diagnosis can be challenging, and timely management is of the utmost importance. Meningoencephalitis i...

6 Syys 202318min

Diabetes mellitus in old critically ill COVID-19 patients

Diabetes mellitus in old critically ill COVID-19 patients

Several studies have found an association between diabetes mellitus, disease severity and outcome in COVID-19 patients. Old, critically ill patients are particularly at risk. A recent multicentre inte...

30 Elo 202310min

Results from the TAME trial

Results from the TAME trial

International guidelines recommend targeting normocapnia in adults with coma resuscitated after out-of-hospital cardiac arrest. However, normocapnia may be insufficient to restore and maintain adequat...

27 Kesä 202325min

Guidelines for the management of severe community-acquired pneumonia

Guidelines for the management of severe community-acquired pneumonia

Severe community‐acquired pneumonia (sCAP) is a clinical entity to describe ICU-admitted patients with community‐acquired pneumonia (CAP) as they might require organ support, and it is associated with...

24 Touko 202320min

Permissive azotemia during AKI enables more rapid renal recovery and less renal fibrosis

Permissive azotemia during AKI enables more rapid renal recovery and less renal fibrosis

Preclinical models of acute kidney injury (AKI) consistently demonstrate that a uremic milieu enhances renal recovery and decreases kidney fibrosis. Reduced renal clearance has the surprising and count...

17 Touko 202343min

How to manage coagulopathies in critically ill patients

How to manage coagulopathies in critically ill patients

Coagulopathy is a severe and frequent complication in critically ill patients, for which the pathogenesis and presentation may be variable depending on the underlying disease. Therefore, a review has ...

10 Touko 202320min

End of Life Care concepts in intensive care

End of Life Care concepts in intensive care

End-of-life care is an approach to a terminally ill patient that shifts the focus of care to symptom control, comfort, dignity, quality of life, and quality of dying rather than treatments aimed at cu...

3 Touko 202330min

Suosittua kategoriassa Liike-elämä ja talous

sijotuskasti
psykopodiaa-podcast
mimmit-sijoittaa
rss-rahapodi
rss-lahtijat
rss-rahamania
rss-neuvottelija-sami-miettinen
rahapuhetta
ostan-asuntoja-podcast
rss-porssipuhetta
rss-laakispodi
rss-h-asselmoilanen
rss-startup-ministerio
rss-bisnesta-bebeja
taloudellinen-mielenrauha
pomojen-suusta
sijoituspodi
rss-rikasta-elamaa
rss-yrittajat-ymparillani
rss-porssipodi