Ep 156 Retinoids Part 1: How it started…

Ep 156 Retinoids Part 1: How it started…

That little bottle of retinol serum sitting on your bathroom counter - what do you know about its history? This week, we’re digging deep into the man behind the medicine, renowned dermatologist Dr. Albert Kligman, and the unethical research he conducted at Holmesburg Prison in the mid-20th century. Kligman’s research program at Holmesburg spanned decades, involved dozens of experiments (including tretinoin) and thousands of individuals, received ample funding from public universities and many pharmaceutical companies, and was generally praised until it all came crashing down in the early 1970s. But, as we’ll discover, the unethical behavior persisted even after the program’s closure as Kligman fought to get tretinoin to market. The murky history of retinoids might be a bit too long to include on the label, but this episode forces us to consider the human cost of a household product and the importance of acknowledging that history.

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Ep 200 Poop Part 1: How the sausage gets made

Ep 200 Poop Part 1: How the sausage gets made

It might be stinky and it might be unpleasant to behold, but we all do it. For many of us, our poop is out of sight, out of mind once we flush it away. But for the next hour and fifteen minutes or so,...

10 Helmi 1h 11min

Special Episode: Nicola Twilley & Frostbite

Special Episode: Nicola Twilley & Frostbite

For much of the world, refrigeration is such a commonplace technology that we rarely stop to wonder at the many ways it has transformed our lives. From the foods we grow to where we grow them, from ho...

3 Helmi 1h

Ep 199 Sleep Part 2: Predictably unpredictable

Ep 199 Sleep Part 2: Predictably unpredictable

Now that we know just how critical sleep is, we’re all making sure we get the amount we need, right? Unfortunately no. One-third to one-half of Americans are not getting enough sleep, according to pub...

27 Tammi 1h 10min

Ep 198 Sleep Part 1: Sleeping with one eye open

Ep 198 Sleep Part 1: Sleeping with one eye open

Sleep is a universal experience. It’s not just the lion that sleeps tonight - it’s also the butterfly, the chicken, the jellyfish, the dog, the snake, the worm, and of course the human. What is this w...

20 Tammi 1h 14min

Special Episode: Daniel Stone & American Poison

Special Episode: Daniel Stone & American Poison

The widespread use of leaded gasoline in the 20th century led to one of the world’s biggest public health and environmental disasters, the effects of which are still present today. Since its developme...

13 Tammi 57min

Ep 197 Detox: Enemas for everyone

Ep 197 Detox: Enemas for everyone

Ah, the new year. After the last month and a half of indulgent food and drink, disrupted schedules, and laying around the house, who doesn’t feel like they’re in need of a whole-body cleanse? There ar...

6 Tammi 1h 16min

From the Vault - Endometriosis: Menstrual Backwash (Ep 88)

From the Vault - Endometriosis: Menstrual Backwash (Ep 88)

This episode originally aired on January 11th, 2022. Chances are you know someone with endometriosis, or perhaps you’re affected yourself. But despite its incredibly high prevalence, endo remains almo...

30 Joulu 20252h 11min

From the Vault - Hepatitis B: Hepatiti, Take 2 (Ep 89)

From the Vault - Hepatitis B: Hepatiti, Take 2 (Ep 89)

This episode originally aired on January 25th, 2022. In light of the recent changes by RFK jr’s Advisory Committee on Immunization Practices (ACIP) to eliminate the universal birth dose of the hepatit...

23 Joulu 20251h 30min

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