112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

Jaksot(416)

267 | Benjamin Breen on Margaret Mead, Psychedelics, and Utopia

267 | Benjamin Breen on Margaret Mead, Psychedelics, and Utopia

The twentieth century was something, wasn't it? Margaret Mead, as well as her onetime-husband Gregory Bateson, managed to play roles in several of its key developments: social anthropology and its imp...

26 Helmi 20241h 13min

266 | Christoph Adami on How Information Makes Sense of Biology

266 | Christoph Adami on How Information Makes Sense of Biology

Evolution is sometimes described -- not precisely, but with some justification -- as being about the "survival of the fittest." But that idea doesn't work unless there is some way for one generation t...

19 Helmi 20241h 20min

AMA | February 2024

AMA | February 2024

Welcome to the February 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

12 Helmi 20243h 24min

265 | John Skrentny on How the Economy Mistreats STEM Workers

265 | John Skrentny on How the Economy Mistreats STEM Workers

Universities and their students are constantly being encouraged to produce more graduates majoring in STEM fields -- science, technology, engineering, and mathematics. That's the kind of training that...

5 Helmi 20241h 20min

264 | Sabine Stanley on What's Inside Planets

264 | Sabine Stanley on What's Inside Planets

The radius of the Earth is over 6,000 kilometers, but the deepest we've ever dug below the surface is only about 12 km. Yet we have a quite reliable idea of the structure of the Earth's interior -- in...

29 Tammi 20241h 12min

263 | Chris Quigg on Symmetry and the Birth of the Standard Model

263 | Chris Quigg on Symmetry and the Birth of the Standard Model

Einstein's theory of general relativity is distinguished by its singular simplicity and beauty. The Standard Model of Particle Physics, by contrast, is a bit of a mess. So many particles and interacti...

22 Tammi 20241h 26min

262 | Eric Schwitzgebel on the Weirdness of the World

262 | Eric Schwitzgebel on the Weirdness of the World

Scientists and philosophers sometimes advocate pretty outrageous-sounding ideas about the fundamental nature of reality. (Arguably I have been guilty of this.) It shouldn't be surprising that reality,...

15 Tammi 20241h 20min

261 | Sanjana Curtis on the Origins of the Elements

261 | Sanjana Curtis on the Origins of the Elements

In mid-20th-century cosmology, there was a debate over the origin of the chemical elements. Some thought that they could be produced in the Big Bang, while others argued that they were made inside sta...

8 Tammi 20241h 7min

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