112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

Jaksot(416)

255 | Michael Muthukrishna on Developing a Theory of Everyone

255 | Michael Muthukrishna on Developing a Theory of Everyone

A "Theory of Everything" is physicists' somewhat tongue-in-cheek phrase for a hypothetical model of all the fundamental physical interactions. Of course, even if we had such a theory, it would tell us...

30 Loka 20231h 17min

254 | William Egginton on Kant, Heisenberg, and Borges

254 | William Egginton on Kant, Heisenberg, and Borges

It can be tempting, when first introduced to a deep concept of physics like Heisenberg's uncertainty principle, to draw grand philosophical conclusions about the impossibility of knowing anything prec...

23 Loka 20231h 6min

253 | David Deutsch on Science, Complexity, and Explanation

253 | David Deutsch on Science, Complexity, and Explanation

David Deutsch is one of the most creative scientific thinkers working today, who has as a goal to understand and explain the natural world as best we can. He was a pioneer in quantum computing, and ha...

16 Loka 20231h 42min

AMA | October 2023

AMA | October 2023

Welcome to the October 2023 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pat...

9 Loka 20232h 58min

252 | Hannah Ritchie on Keeping Hope for the Planet Alive

252 | Hannah Ritchie on Keeping Hope for the Planet Alive

Our planet and its environment are in bad shape, in all sorts of ways. Those of us who want to improve the situation face a dilemma. On the one hand, we have to be forceful and clear-headed about how ...

2 Loka 20231h 15min

251 | Rosemary Braun on Uncovering Patterns in Biological Complexity

251 | Rosemary Braun on Uncovering Patterns in Biological Complexity

Biological organisms are paradigmatic emergent systems. That atoms of which they are made mindlessly obey the local laws of physics; even cells and organs do their individual jobs without explicitly u...

25 Syys 20231h 11min

250 | Brendan Nyhan on Navigating the Information Ecosystem

250 | Brendan Nyhan on Navigating the Information Ecosystem

The modern world inundates us with both information and misinformation. What are the forces that conspire to make misinformation so prevalent? Can we combat the flow of misinformation, perhaps by lega...

18 Syys 202357min

249 | Peter Godfrey-Smith on Sentience and Octopus Minds

249 | Peter Godfrey-Smith on Sentience and Octopus Minds

The study of cognition and sentience would be greatly abetted by the discovery of intelligent alien beings, who presumably developed independently of life here on Earth. But we do have more than one d...

11 Syys 20231h 28min

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