The importance of vaccine safety when developing a new vaccine with Professor Kathryn Edwards

The importance of vaccine safety when developing a new vaccine with Professor Kathryn Edwards

In episode 2 of our ‘COVID19 Road to a vaccine series’, Associate Professor Nigel Crawford, from the Murdoch Children’s Research Institute (MCRI), Melbourne, Australia, speaks with Professor Kathryn Edwards. Dr Edwards is a professor of paediatrics in the division of infectious diseases at Vanderbilt University School of Medicine in Nashville, Tennessee, where she is also vice-chair for clinical research. She is an internationally-recognised expert in vaccinology and, in particular, vaccine safety.

They will be discussing the important topic of vaccine safety when developing a new vaccine, including some of the challenges faced in the COVID19 vaccine development pathway.

In this episode they discuss:

•Professor Edwards' perspective on vaccine safety across her roles as a clinician/scientist/researcher
•Adverse events following immunisation and their implications when developing new vaccines
•Vaccine safety across the different phases (I to IV) of clinical trials
•The importance of data safety and monitoring committees in vaccine trials
•What we can learn from the historical research into the development of SARS and MERS vaccines
•What is ADE (antibody-dependent enhancement of virus infection) and why is it an important consideration in COVID19 vaccine development?
•What are adjuvants and how does the use of them affect safety planning?
•Should pregnant women and children be involved in vaccine trials and how can their participation be managed safely?
•The importance of transparency and honest communication with the public in regards to vaccine safety

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Jaksot(18)

The final episode of COVID19 Road to a vaccine with Professor Walter Orenstein

The final episode of COVID19 Road to a vaccine with Professor Walter Orenstein

In the final episode of this podcast series our host, Associate Professor Nigel Crawford, speaks with Professor Walter Orenstein. Dr Orenstein is a Professor of Medicine, Epidemiology, Global Health a...

23 Marras 202031min

How the COVID-19 pandemic is being managed in British Columbia, Canada, with Dr Bonnie Henry

How the COVID-19 pandemic is being managed in British Columbia, Canada, with Dr Bonnie Henry

In episode 17 of our COVID19 Road to a vaccine series, our host, Associate Professor Nigel Crawford, speaks to Dr Bonnie Henry, the provincial health officer (PHO) for the Province of BC in Canada. As...

16 Marras 202026min

COVID-19 vaccine candidates regulatory process update with Professor Norman Baylor

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In episode 16 of our COVID19 Road to a vaccine series, our host, Associate Professor Nigel Crawford speaks once again with Professor Norman Baylor. Professor Baylor is the former Director of the Offic...

1 Marras 202027min

Ethical considerations on the road to a COVID-19 vaccine with Professor Lynn Gillam

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In episode 15, our host, Associate Professor Nigel Crawford, speaks to Professor Lynn Gillam. Lynn is a clinical ethicist who trained in philosophy and bioethics. She is a Professor in the Centre for ...

4 Loka 202032min

Vaccine acceptance with Dr Bruce Gellin

Vaccine acceptance with Dr Bruce Gellin

In episode 14, our host, Associate Professor Nigel Crawford, speaks to Dr Bruce Gellin. Bruce is the President of Global Immunization at the Sabin Vaccine Institute in Washington. The Sabin Vaccine In...

23 Syys 202032min

Global issues brought about by SARS-CoV-2 with Professor Kim Mulholland

Global issues brought about by SARS-CoV-2 with Professor Kim Mulholland

In episode 13, our host, Associate Professor Nigel Crawford, speaks to Professor Kim Mulholland. Kim is a paediatrician and Professor of Child Health from the Murdoch Children’s Research Institute, th...

13 Syys 202026min

Vaccine confidence from a global perspective with Professor Heidi Larson

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In this episode of COVID19 Road to a vaccine, our host, Associate Professor Nigel Crawford, speaks to Professor Heidi Larson. Heidi is an anthropologist and Director of the Vaccine Confidence Project ...

6 Syys 202022min

Vaccine confidence with Associate Professor Margie Danchin and Professor Julie Leask

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In episode 11 of our COVID19 Road to a vaccine series, our host, Nigel Crawford, speaks toexperts in vaccine confidence, Associate Professor Margie Danchin and Professor Julie Leask. Margie is a consu...

31 Elo 202027min

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