127. Guidelines, COVID, Econsults, COVID19, CDC

127. Guidelines, COVID, Econsults, COVID19, CDC

https://covid19treatmentguidelines.nih.gov/
A National Institutes of Health panel has released new guidelines
against use of hydroxychloroquine plus azithromycin outside of clinical trials

https://www.ncbi.nlm.nih.gov/pubmed/32001253
Anaphylaxis—a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis

Epinephrine is the cornerstone of anaphylaxis management but continues to be underutilized



ANTIBODY—

https://jamanetwork.com/journals/jama/fullarticle/2764954



“Yet, according to Theel, several companies are marketing lateral flow assays as rapid point-of-care tests to identify active COVID-19, something the FDA announced it will take action against. “We do not really know how well these assays work at this point,” Theel said in a follow-up email.”


https://www.sccgov.org/sites/covid19/Pages/press-release-04-21-20-early.aspx
They say the Santa Clara Medical Examiner identified two individuals who died at home on February 6, 2020 and February 17, 2020. And the autopsy came with……..positive for SARS-CoV-2.

https://www.cdc.gov/mmwr/index.html
Titled – Assessment of SARS-CoV-2 Infection Prevalence in Homeless Shelters — Four U.S. Cities, March 27–April 15, 2020
They used PCR to test resident and staff members at 19 homeless shelters- almost 1500 people in total and it was impressive that in those locations for which there was already at least two previous COVID19 test found the rate of positive cases was extremely high

— 17% of residents and staff members in Seattle; roughly 35% of those tested in Boston; and 66% of the residents in san Francisco. This tells us what we already know, this disease spreads like wild fire, of those that it spreads not




https://annals.org/aim/fullarticle/2764585/utility-appropriateness-content-electronic-consultations-across-medical-subspecialties-cohort-study
Utility, Appropriateness, and Content of Electronic Consultations Across Medical Subspecialties: A Cohort Study
Objective of this retrospective cohort study was to assess novel metrics of electronic consult appropriateness and utilityTo assess novel metrics of e-consult appropriateness and To assess novel metrics of e-consult appropriateness and To assess novel metrics of e-consult appropriateness and To assess novel metrics of e-consult appropriateness and To assess novel metrics of e-consult appropriateness.
Most consultations were answered within one day and approximately 70% of the consultations that all 4 criteria for appropriateness indicating about 70% of time the patient could be spared a visit to a specialist and have a better conditions managed by the primary care provider with just subtle guidance from the specialistMost consultations were answered within 1 day, with variation across specialties (73.1% for psychiatry to 87.8% for infectious disease). Overall, 70.2% of e-consults met all 4 criteria for appropriateness; the frequency of unmet criteria varied among specialties.









Jaksot(385)

Episode 359: 258. Oral Antibiotics and Risk of Serious Cutaneous Adverse Drug Reactions

Episode 359: 258. Oral Antibiotics and Risk of Serious Cutaneous Adverse Drug Reactions

https://jamanetwork.com/journals/jama/article-abstract/2822097Design, Setting, and Participants  Nested case-control study using population-based linked administrative datasets among adults aged 66 ye...

3 Tammi 20255min

Episode 358: 257. Twice-Yearly Lenacapavir or Daily F/TAF for HIV Prevention

Episode 358: 257. Twice-Yearly Lenacapavir or Daily F/TAF for HIV Prevention

https://www.nejm.org/doi/full/10.1056/NEJMoa2407001ConclusionsNo participants receiving twice-yearly lenacapavir acquired HIV infection. HIV incidence with lenacapavir was significantly lower than bac...

30 Joulu 20246min

Episode 357: 256. Medications for alcohol-use disorder and follow-up after hospitalization

Episode 357: 256. Medications for alcohol-use disorder and follow-up after hospitalization

Allaudeen N et al. Medications for alcohol-use disorder and follow-up after hospitalization for alcohol withdrawal: A multicenter study. J Hosp Med 2024 Dec; 19:1122. (https://doi.org/10.1002/jhm.1345...

27 Joulu 20245min

Episode 356: 255. Real-world use of glucocorticoids for adults hospitalized with community-acquired pneumonia

Episode 356: 255. Real-world use of glucocorticoids for adults hospitalized with community-acquired pneumonia

Real‐world use of glucocorticoids and clinical outcomes in adults hospitalized with community‐acquired pneumonia on medical wards - Malecki - 2024 - Journal of Hospital Medicine - Wiley Online Library...

23 Joulu 20246min

Episode 355: 254. 2024 ESC Guidelines for the management of elevated blood pressure and hypertension

Episode 355: 254. 2024 ESC Guidelines for the management of elevated blood pressure and hypertension

2024 ESC guidelines propose a simple new BP categorization: Non-elevated: less than 120/70 mm Hg in the office (pharmacological treatment is not recommended). Elevated: 120 to 139/70 to 89 mm Hg (phar...

20 Joulu 20248min

Episode 354: 253. Centralized Colorectal Cancer Screening Outreach in Federally Qualified Health Centers

Episode 354: 253. Centralized Colorectal Cancer Screening Outreach in Federally Qualified Health Centers

Question  Does adding centralized mailed fecal immunochemical testing and patient navigation to usual care improve colorectal cancer (CRC) screening in US federally qualified health centers? pragmatic...

18 Joulu 20247min

Episode 353: 252. 2.4 Million to Prevent 4 Hospitalizations!

Episode 353: 252. 2.4 Million to Prevent 4 Hospitalizations!

Packer M et al. Tirzepatide for heart failure with preserved ejection fraction and obesity. N Engl J Med 2024 Nov 16; [e-pub].https://doi.org/10.1056/NEJMoa2410027  In the industry-funded SUMMIT trial...

13 Joulu 202411min

Episode 352: 251. Safety of Triptans in Patients Who Have or Are at High Risk for Cardiovascular Disease

Episode 352: 251. Safety of Triptans in Patients Who Have or Are at High Risk for Cardiovascular Disease

Wang Z et al. Safety of triptans in patients who have or are at high risk for cardiovascular disease: A target trial emulation. Mayo Clin Proc 2024 Nov; 99:1722. (https://doi.org/10.1016/j.mayocp.2024...

12 Joulu 20246min

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