Episode 171: 171.  Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

Episode 171: 171. Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

SGLT2 inhibitors and GLP1 agonists administered without metformin compared to other glucose‐lowering drugs in patients with type 2 diabetes mellitus to prevent cardiovascular events: A systematic review - Escobar - 2021 - Diabetic Medicine - Wiley Online Library

Yes these fancy new drugs work with and without metformin but that does not mean these drugs should be first line!!


Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network


Yep even 200,000IU of vit D does nothing except raise your vit d level.

Diet and acne: review of the evidence from 2009 to 2020 - Dall’Oglio - - International Journal of Dermatology - Wiley Online Library


What you eat does mess with your acne, or at least says this large observational trial.


Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials | The BMJ

The muscle aches with statins is a common event that it occurs as frequently with the active drug as it does with placebo

Jaksot(385)

102. DOAC and hematuria  plus a listener question

102. DOAC and hematuria plus a listener question

https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2739056 not all guidelines are equal, think for yourself. Some guidelines even do harm when you actually look at the evidence. h...

2 Syys 201928min

101. 3A- Aspirin, Asthma, AntiPlatelet

101. 3A- Aspirin, Asthma, AntiPlatelet

https://www.nejm.org/doi/full/10.1056/NEJMoa1813959 even when we dont know where the stroke is coming from- aspirin is still king all these years later https://www.thelancet.com/journals/lancet/artic...

13 Elo 201921min

100. 3H episode= Hakuna Matata, HIV, and HPV

100. 3H episode= Hakuna Matata, HIV, and HPV

https://www.cdc.gov/mmwr/volumes/68/wr/mm6825a2.htm we are not testing people for HIV even though guidelines https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/human-im...

2 Elo 201925min

Got 99 (episodes) and an IMPORTANT Article Before It's Done

Got 99 (episodes) and an IMPORTANT Article Before It's Done

https://www.ncbi.nlm.nih.gov/pubmed/30608562 A1C level low is not good and high is not good cause both seem to wind up have you the pt. in the hospital for hypoglycemia- the low point of the U curve ...

24 Heinä 201918min

98. A New Drug, Sugar Legacy, Statin in the Elderly

98. A New Drug, Sugar Legacy, Statin in the Elderly

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31942-1/fulltext If you are over 70 or 75 and primary prevention then likely no benefit in statins and secondary benefit is very sm...

12 Heinä 201922min

97. Old Women Walking, Energy Drinks, and Antibiotics

97. Old Women Walking, Energy Drinks, and Antibiotics

https://www.ahajournals.org/doi/10.1161/JAHA.118.011318 energy drinks prolong the QT just ever so slightly in healthy 22yr olds so if you are thinking of telling grandma to slam 32ounces of energy d...

27 Kesä 201925min

96. Sprinting to Induction of Clopidogrel

96. Sprinting to Induction of Clopidogrel

vitamin d- if you cant give up on it then give up on checking the lab value- fire and forget. https://www.nejm.org/doi/full/10.1056/NEJMoa1800566 induction at 39 weeks is okay with me https://jamane...

14 Kesä 201926min

94. New Afib Guidelines, New standard for SK, and Foley cath + UTI

94. New Afib Guidelines, New standard for SK, and Foley cath + UTI

afib- new guidelines! https://www.google.com/search?q=2019+American+Heart+Association%2C+American+College+of+Cardiology+and+the+American+Rhythm+Society+focused+update+from+their+2014+guidelines+for+...

21 Touko 201925min

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