Episode 270: 269. What is the Harm in Aspirin?

Episode 270: 269. What is the Harm in Aspirin?

The trial was terminated after 1015 patients with atrial cardiopathy had been randomized to receive either apixaban or aspirin for a mean follow-up of 1.8 years, recurrent stroke rates were identical (40 events per group; 4.4% annualized rate). There were 7 symptomatic intracranial hemorrhages in the aspirin group and none in the apixaban group, though other major hemorrhages occurred at similar rates

Aspirin is not benign and has real risk--

BTW don't give anticoagulation if the patient does not have atrial fib.

https://jamanetwork.com/journals/jama/article-abstract/2814933

Jaksot(385)

Episode 238: 238. What to do With Low Risk Pulmonary Embolism?

Episode 238: 238. What to do With Low Risk Pulmonary Embolism?

Use the PE Severity Index. If low risk and that is the only reason for admission, then the patient is safe for dischargehttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(11)60824-6/abstr...

12 Helmi 20245min

Episode 237: 237. Big Take Away from ACP Update to Colon Cancer Screening

Episode 237: 237. Big Take Away from ACP Update to Colon Cancer Screening

american college of physicians says- No need to start colon cancer screening prior to 50. stop at age 75 or with 10 yrs of life left and FIT testing can be every other year and Cologuard is not recomm...

9 Helmi 20245min

Episode 236: 236. Is Weight Loss Beneficial For Hip Osteoarthritis?

Episode 236: 236. Is Weight Loss Beneficial For Hip Osteoarthritis?

While weight loss may be beneficial for individuals with knee osteoarthritis, it does not see to have a protective or beneficial effect for those with hip osteoarthritis. https://agsjournals.onlinelib...

8 Helmi 20244min

Episode 235: 235. When Should A Patient With HIV Be Started On Statin Therapy?

Episode 235: 235. When Should A Patient With HIV Be Started On Statin Therapy?

In patients with HIV and cv risk score of 4.5% there was a NNT of 106 at 5 yrs of follow up to prevent 1 MACEhttps://www.acpjournals.org/doi/10.7326/M22-2643?url_ver=Z39.88-2003&rfr_id=ori:rid:crossre...

7 Helmi 20244min

Episode 234: 234. Does Size Matter...BP Cuff Size

Episode 234: 234. Does Size Matter...BP Cuff Size

A cuff 1-2 sizes too large underestimated bp by 4-9mm Hg BUT a cuff 1-2 sizes too small overestimated the BP 4-20mm Hghttps://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2807853

6 Helmi 20245min

Episode 233: 233. Do GLP1 agonist actually delay gastric emptying?

Episode 233: 233. Do GLP1 agonist actually delay gastric emptying?

GLP1 agonist likely lead to retained gastric products but this effect is larger for once weekly injections than once daily pills.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204182/

5 Helmi 20246min

Episode 232: 232. Is the HPV vaccine that good?

Episode 232: 232. Is the HPV vaccine that good?

During 28 months of follow-up, absolute risks for progression from CIN2 to CIN3 (or worse) were as follows: 23% among women vaccinated before age 15 32% among women vaccinated between ages 15 and 20 3...

2 Helmi 20248min

Episode 231: 231. Is Cancer Actually Associated with Weight Loss?

Episode 231: 231. Is Cancer Actually Associated with Weight Loss?

>10% unintentional weight loss is most likely associated with  gastrointestinal, liver, pancreatic, and biliary cancers (relative risks, 3.1–7.4); Leukemia (RR, 4.2) Breast, prostate, and gynecologic ...

1 Helmi 20245min

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