Episode 289: 288. An RCT for Time Restricted Eating!

Episode 289: 288. An RCT for Time Restricted Eating!

41 adults (mean age, 59) with obesity (mean weight, 99 kg) and prediabetes or diet-controlled diabetes – everyone got the same diet. Same micro- and macronutrient composition; same calorie amounts

Food was prepared in a study kitchen and consumed onsite or taken home.

Key difference

The intervention group was instructed to eat between 8 a.m. and 6 p.m. and to consume 80% of calories by 1 p.m. The control group was instructed to eat between 8 a.m. and midnight, with 55% of calories after 5 p.m.


Weight loss in the two groups was similar at 12 weeks (about 2.4 kg).

3 months—and no difference—


https://www.acpjournals.org/doi/10.7326/M23-3132

Jaksot(386)

Episode 335: 334. Do Thicken Liquids Prevent Dysphagia?

Episode 335: 334. Do Thicken Liquids Prevent Dysphagia?

Oropharyngeal dysphagia is highly prevalent in hospitalized patients with Alzheimer disease or other dementias. These patients often are prescribed thick liquid diets Makhnevich A et al. Thick liquids...

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Episode 334: 333. Cell Phone Use While Driving and Financial Gain

Episode 334: 333. Cell Phone Use While Driving and Financial Gain

Feedback and Financial Incentives for Reducing Cell Phone Use While Driving: A Randomized Clinical Trial | Public Health | JAMA Network Open | JAMA Network  Question  Can behavioral interventions decr...

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Episode 333: 331. Noncontrast CT Selected Thrombectomy vs Medical Management

Episode 333: 331. Noncontrast CT Selected Thrombectomy vs Medical Management

Noncontrast CT Selected Thrombectomy vs Medical Management for Late-Window Anterior Large Vessel Occlusion | Neurology Most studies that have shown a benefit from endovascular thrombectomy (EVT) for i...

24 Syys 20246min

Episode 332: 330. Does a Multivitamine a Day Keep The Death Away?

Episode 332: 330. Does a Multivitamine a Day Keep The Death Away?

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2820369With as many as 1 in 3 US adults using multivitamin supplements, the question as to whether these supplements reduce mortality They ...

18 Syys 20246min

Episode 331: 329. Should We Give AceI or ARBs to Patients with CKD 4 and 5?

Episode 331: 329. Should We Give AceI or ARBs to Patients with CKD 4 and 5?

https://www.acpjournals.org/doi/10.7326/M23-3236Angiotensin-converting–enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs) seldom are initiated among patients with chronic kidney disease (...

17 Syys 20247min

Episode 330: 328. Methods Monday, Composite Endpoints

Episode 330: 328. Methods Monday, Composite Endpoints

Composite outcomes You add multiple outcomes together… this is great because you can increase the event rate.. if you are just looking at death lots of people might now die but if you look at death an...

16 Syys 202411min

Episode 329: 327. A Cell-free DNA Blood-Based Test for Colorectal Cancer Screening "SHIELD TESTING"

Episode 329: 327. A Cell-free DNA Blood-Based Test for Colorectal Cancer Screening "SHIELD TESTING"

ening, the offer of a blood-based screening test boosted CRC screening by 17.5 percentage points over usual care.That is becauseCRC screening proportions were 17.5 percentage points higher in the bloo...

23 Elo 202412min

Episode 328: 327. Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk

Episode 328: 327. Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk

https://pubmed.ncbi.nlm.nih.gov/38945140/The primary outcome was a composite of myocardial infarction, revascularisation, hospitalisation for heart failure, stroke, or death from cardiovascular causes...

2 Elo 20247min

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