Episode 289: 288. An RCT for Time Restricted Eating!

Episode 289: 288. An RCT for Time Restricted Eating!

41 adults (mean age, 59) with obesity (mean weight, 99 kg) and prediabetes or diet-controlled diabetes – everyone got the same diet. Same micro- and macronutrient composition; same calorie amounts

Food was prepared in a study kitchen and consumed onsite or taken home.

Key difference

The intervention group was instructed to eat between 8 a.m. and 6 p.m. and to consume 80% of calories by 1 p.m. The control group was instructed to eat between 8 a.m. and midnight, with 55% of calories after 5 p.m.


Weight loss in the two groups was similar at 12 weeks (about 2.4 kg).

3 months—and no difference—


https://www.acpjournals.org/doi/10.7326/M23-3132

Jaksot(386)

119. Aimovig or Erenumab Prescription Description

119. Aimovig or Erenumab Prescription Description

A listener wrote in with a question about a drug, this is my response. Let me know your thoughts? Would you prescribe this drug? Andrewbuelt@gmail.comhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa1705848

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118. Choosing Wisely, Statins for Stroke, and Physical Therapy first

118. Choosing Wisely, Statins for Stroke, and Physical Therapy first

There was a paper to start the year that got a lot of hype saying that just maybe we should target an LDL but that is not what the study actually showed and I will tell you why I think it is wrong.

8 Maalis 202022min

117. The Benefits on Healthy lifestyle and Nutrition

117. The Benefits on Healthy lifestyle and Nutrition

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2757311?widget=personalizedcontent&previousarticle=2757307 Prior authorization requirements increased from 8% to approximately 24% of...

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116. Conflicts of Vaccine, Understanding Sunscreen, and UPTODATE

116. Conflicts of Vaccine, Understanding Sunscreen, and UPTODATE

https://annals.org/aim/fullarticle/2760034/disclosure-form-work-submitted-medical-journals-proposal-from-international-committee. disclose everything for the papers that you keep..or writePatient comp...

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115. Part 3 of the Top Articles of 2019

115. Part 3 of the Top Articles of 2019

Try not to read these all at once!!https://www.ncbi.nlm.nih.gov/pubmed/30715088 https://www.bmj.com/content/365/bmj.l2006 https://www.ncbi.nlm.nih.gov/pubmed/30359476 https://www.ncbi.nlm.nih.gov/pub...

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114. Top Articles of 2019 Part 2

114. Top Articles of 2019 Part 2

No summary YET! I promise it is coming, but here are a few more articles I think were pretty impressive from 2019.

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113. Top articles of 2019 part 1

113. Top articles of 2019 part 1

It is that time of year again-- Top articles of 2019 part 1. This is my opinion, but I think it is a pretty good opinion.

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112. Grade B, COPD, and Facebook for HIV

112. Grade B, COPD, and Facebook for HIV

https://jamanetwork.com/journals/jama/fullarticle/2751726 uspstf now grade B for asymptomatic urine in preggohttps://pediatrics.aappublications.org/content/144/6/e20192739kids do shoot their eye out!h...

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