Episode 312: 311. Risk of Stroke in Women Using Levonorgestrel-Releasing Intrauterine Device for Contraception

Episode 312: 311. Risk of Stroke in Women Using Levonorgestrel-Releasing Intrauterine Device for Contraception

https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.124.047438



We studied the risk of IS and ICH in women using LG-IUDs—aka mirana-- compared to women not using hormonal contraceptives.

The commonly used combined hormonal contraceptives with progestins and ethinylestradiol are associated with an increased risk of ischemic stroke (IS).

In this Danish historical cohort study (2004-2021) we followed non-pregnant women (18-49 years) registering incident IS and ICH in relation to use of LG-IUD/non-use of hormonal contraceptives utilizing Danish high-quality registries with nation-wide coverage.

A total of 1,681,611 non-pregnant women A total of 1,681,611 non-pregnant women

The numbers get huge here however--

After adjustment incidence rate ratio for IS was 0.78 (CI: 0.70; 0.88), and for ICH it was 0.94 (CI: 0.69; 1.28)

Use of LG-IUD was associated with a 22% lower incidence rate of IS without raising incidence rate of ICH. I think IUD are unutilized and now we have data that says they have lowers rates of stroke.

Jaksot(385)

15. Clinical Testing

15. Clinical Testing

An overview of a few studies and information regarding inpatient and outpatient testing. "The first principle of solid wisdom is discretion.." --Norman MacDonald. A little discussion on understanding ...

21 Loka 201432min

14. IV Fluids part 2

14. IV Fluids part 2

Bottoms up on the last discussion on fluids and a review of a few of the trials that contribute to the current mindset in EBM. Andrew creates his own "Mike Tyson Theory of fluids" and Joe subscribes t...

3 Loka 201424min

13. IV Fluids part 1

13. IV Fluids part 1

A quick discussion one the topic of which patient to give which fluid. Review of studies from the 90s to 2014 with demographics including pre/post Operative, Septic patient and even Rattus Rattus. (th...

25 Syys 201423min

12. Dexa Scan Part 2

12. Dexa Scan Part 2

Hard topic and difficult discussion continues about reasonable intervention and evaluation of therapy for osteoporosis. Andrew starts right off with his personal recommendation on the screening of low...

10 Syys 20147min

11. The Dexa Scam

11. The Dexa Scam

Hard hitting discussion on the evidence on soft bones and the best screening and treatment options. This episode was broken into two parts because Joe needed to run a full NIH Stroke Scale on Andrew m...

1 Syys 201429min

10. Vitamin D Part 2

10. Vitamin D Part 2

Who and when to test. Dose and frequency along with route of administration of Vitamin D are discussed along with 12 studies of outcomes and complications/benefits of each. Joe discovers Andrew is bel...

13 Elo 201431min

8. Watch Were You Are Putting Your Hands...

8. Watch Were You Are Putting Your Hands...

You might be outside the guidelines soon. Joe and Andrew discuss the newest recommendations from ACP regarding bimanual/pelvic exams. Andrew can't hold it any longer and breaks into song for the first...

6 Heinä 201434min

7. Diabetes. It's Not Over Until the Intervals Are Over.

7. Diabetes. It's Not Over Until the Intervals Are Over.

Don't celebrate just yet, the confidence intervals aren't all the way over the line. Andrew gives yet another history lesson on the improvements in Diabetes and runs over some of the recent talk abou...

23 Kesä 201430min

Suosittua kategoriassa Terveys ja hyvinvointi

unicast
tiedenaiset-podcast
psykopodiaa-podcast
voi-hyvin-meditaatiot-2
rss-pitaisko-erota
meditaatiot-suomeksi
vakeva-elama-viisaampi-mieli-vahvempi-keho
junnut-pelissa
rss-mighty-finland-podcast
puhu-muru
rss-narsisti
rss-kuumilla-aalloilla
rss-uplevel-by-sonja-hannus
rss-pt-paahtio
rss-vapaudu-voimaasi
mielen-puolikkaat
terapiassa
rss-nautinto
aamukahvilla
rss-en-saa-unta