Episode 320: 319. President Biden has COVID, Should the First Lady Take Paxlovid?
Questioning Medicine18 Heinä 2024

Episode 320: 319. President Biden has COVID, Should the First Lady Take Paxlovid?

https://www.nejm.org/doi/full/10.1056/NEJMoa2309002
In this placebo-controlled trial, postexposure prophylaxis with nirmatrelvir–ritonavir for 5 or 10 days did not significantly reduce the risk of symptomatic SARS-CoV-2 infection.


https://www.nejm.org/doi/full/10.1056/NEJMoa2309003

https://www.nejm.org/doi/full/10.1056/NEJMoa2118542


Pfizer has some serious problems! #pfizer

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Episode 222: 222. Ablation for AFIB in patients with HFrEF

Episode 222: 222. Ablation for AFIB in patients with HFrEF

Consider ablation in patients who have an EF < 35% and atrial fibrillation the NNT for all cause mortality was 7 at 18 months https://www.nejm.org/doi/full/10.1056/NEJMoa2306037

19 Tammi 20244min

Episode 221: 221. Nurse Led Sleep Restriction IMPROVES Insomnia

Episode 221: 221. Nurse Led Sleep Restriction IMPROVES Insomnia

Sleep restriction therapy led by nurses with only 4 hours of education significantly improved patients insomnia at 6 months. More info HERE ___>https://thrive.kaiserpermanente.org/care-near-you/northe...

18 Tammi 20246min

Episode 220: 220. Semaglutide at 1yr Gives Small Improvement in Questionnaire for those with HFpEF

Episode 220: 220. Semaglutide at 1yr Gives Small Improvement in Questionnaire for those with HFpEF

Kansas City Cardiomyopathy Questionnaire clinical summary score was improved by 7.8 in those individuals with HFpEF that took semaglutide for one year compared to those that took placebo. This is a sm...

17 Tammi 20245min

Episode 219: 219. Oral Iron better with vitamin C  on an empty stomach

Episode 219: 219. Oral Iron better with vitamin C on an empty stomach

When taking Ferrous Fumarate a little bit of vitamin C or an 8 ounce glass of orange juice with an otherwise empty stomach will improve the absorption- this absorption is decreased with food and coffe...

16 Tammi 20245min

Episode 218: 218. Semaglutide and CAD But No Diabetes - Decrease Event$$$$$$

Episode 218: 218. Semaglutide and CAD But No Diabetes - Decrease Event$$$$$$

https://www.nejm.org/doi/full/10.1056/NEJMoa2307563Semaglutide and CAD but no diabetes decreases events NNT of 66 at 40 months but a predicted price tag of 3.5 million dollars.

12 Tammi 20247min

Episode 217: 217. Olanzapine 2.5mg for weight gain with advance cancer

Episode 217: 217. Olanzapine 2.5mg for weight gain with advance cancer

Olanzapine 2.5mg for weight gain with advance cancer NNT of 50 for >5% weight gainhttps://pubmed.ncbi.nlm.nih.gov/36977285/

11 Tammi 20245min

Episode 216: 216. AFIB- RATE or ABLATE-- New guidelines

Episode 216: 216. AFIB- RATE or ABLATE-- New guidelines

ACC/AHA just came out with new guidelines on AFIB if you need some light reading material! (big take home rhythm not rate, and not equal, read below for more information) A HUGE piece of new is that n...

27 Joulu 20239min

Episode 215: 215. Enteric coated or uncoated aspirin, which is better or safer?

Episode 215: 215. Enteric coated or uncoated aspirin, which is better or safer?

Effectiveness and Safety of Enteric-Coated vs Uncoated Aspirin in Patients With Cardiovascular Disease: A Secondary Analysis of the ADAPTABLE Randomized Clinical Trial | Clinical Pharmacy and Pharmaco...

20 Joulu 20234min

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