RealTalk MS6 Tammi 2025

Episode 384: Behavioral and Lifestyle Risk Factors for MS with Dr. Jared Bruce and Dr. Amanda Bruce

There are genetic risks associated with MS, there are demographic risks of experiencing a more severe disease course, and there are also behavioral and lifestyle risks that will increase the chance that someone will be diagnosed with MS. Joining me today to discuss behavioral and lifestyle MS risk factors and how they can be mitigated are Doctor Jared Bruce and Dr. Amanda Bruce.

Dr. Jared Bruce is a neuropsychologist and the director of psychiatric research at the University of Missouri-Kansas City School of Medicine. Dr. Amanda Bruce is a clinical psychologist and an assistant professor in the Department of Behavioral Pediatrics at the University of Kansas Medical Center.

We're also reviewing the details of the Inflation Reduction Act, which means, beginning in 2025, significantly lower out-of-pocket costs for prescription medications for the quarter-million people with MS who are on Medicare.

We'll tell you about study results for a novel drug that was effective in remyelination and restoring lost function to mice with the mouse model of MS.

We'll share the details of a study that shows how specific comorbidities affect specific MS outcomes.

We'll review results of a study that shows men with MS who start a high-efficacy disease-modifying therapy experience fewer relapses.

And we'll tell you how an artificial intelligence chatbot soundly beat human experts in predicting the results of neuroscience studies.

We have a lot to talk about! Are you ready for RealTalk MS??!

This Week: Behavioral and Lifestyle risk factors for MS (and how to mitigate them) :22

It's 2025, and that means significant out-of-pocket savings on prescription medications for people with MS on Medicare 1:20

Novel drug shows effectiveness in remyelination and restoring function in mouse model of MS 3:26

Study shows how specific comorbidities affect specific MS outcomes 5:17

Study shows men on high-efficacy disease-modifying therapies experience fewer MS relapses 8:46

Study shows AI beats human experts in predicting results of neuroscience studies 12:22

Dr. Jared Bruce and Dr. Amanda Bruce discuss behavioral and lifestyle MS risk factors 16:43

Share this episode 32:13

Have you downloaded the free RealTalk MS app? 32:33

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LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

RealTalk MS on YouTube
https://www.youtube.com/@RealTalkMS

STUDY: Selective Retinoid X Receptor Agonism Promotes Functional Recovery and Myelin Repair in Experimental Autoimmune Encephalomyelitis
https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-024-01904-x

STUDY: Comorbidities and Their Association with Outcomes In the Multiple Sclerosis Population: A Rapid Review
https://msard-journal.com/article/S2211-0348(24)00519-4/fulltext

STUDY EXPLAINED (Plain English): Comorbidities and Their Association with Outcomes In the Multiple Sclerosis Population: A Rapid Review
https://tremlettsmsresearchexplained.wordpress.com/2024/10/29/comorbidities-and-their-association-with-outcomes-in-the-multiple-sclerosis-population-a-rapid-review-explained

STUDY: Comparative Effectiveness of High-Efficacy and Moderate-Efficacy Disease-Modifying Agents in Reducing the Annualized Relapse Rates Among Multiple Sclerosis Patients in the United States
https://sciencedirect.com/science/article/abs/pii/S0091743524003359

STUDY: Large Language Models Surpass Human Experts in Predicting Neuroscience Results
https://nature.com/articles/s41562-024-02046-9

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RealTalk MS Episode 384
Guests: Dr. Jared Bruce and Dr. Amanda Bruce

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