Letting Go of Calories-In, Calories-Out
Fat Science17 Helmi 2025

Letting Go of Calories-In, Calories-Out

On this episode of Fat Science, it’s time to let go of the old paradigm “calories in, calories out.” Join hosts Dr. Emily Cooper, Andrea Taylor and Mark Wright as they kick CICO to the curb.

The idea that a person’s weight is determined only by the ratio of calories consumed and calories burned is an over-simplification and often not true, especially for people with metabolic dysfunction.

Dr. Cooper reveals the real key to weight management is not calorie counting but understanding metabolic function influenced by the neuroendocrine system. Through personal stories and insights, they explore why diets don’t work and how acknowledging the complexity of metabolism can lead to better health.

Key Takeaways:

  • Caloric intake does not have a static burn rate; it's controlled by dynamic neuroendocrine signals.
  • Metabolic adaptations occur with calorie restriction, reducing metabolic rate, making weight loss unsustainable over the long term.
  • The science holds answers to metabolic dysfunction, revealed by metabolic testing and hormone imbalance recognition.
  • Education and communication can challenge and change the stigma and bias around weight, leading to a more informed society.

Personal Stories & Practical Advice:

  • Andrea shares her journey about ignoring diets and focusing on metabolic health for long-term benefits.
  • Dr. Cooper recounts her challenges in communicating her findings in a positive way, leading to greater acceptance and understanding among patients, healthcare providers and the general public.

Resources:

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org.

Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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