The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld : 1265

Pendulum sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™…molecular biologist and biochemist Colleen Cutcliffe, Ph.D., returns to the show with brand new science about your gut. She’s a regular guest because she and her team at Pendulum continue to uncover innovative ways to improve your gut health, your metabolism, your immune system, how your brain works and how long you live. This time, Akkermansia’s back in the spotlight, with more than 300 new studies showing connections to weight, metabolism and immunity. A unique and novel probiotic strain (species of bacteria) naturally found in your gastrointestinal tract, Akkermansia muciniphila, directly interacts with your gut lining and helps regulate the mucus lining in your gut. Now, there’s growing evidence showing Akkermansia to be a keystone bacterial strain.This conversation dives into the latest research and what it means for you. You’ll learn how to apply this new knowledge and how to boost Akkermansia in your gut.SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://pendulumlife.com and use promo code DAVEVIP to get 20% off your first month of membership. Watch this episode on YouTube!A Pre-Alcohol Probiotic to Offset a Rough Morning After: https://zbiotics.com/dave, use code DAVE to save 15% off your first order. Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Holiday 25% off sale. Through Dec. 31, 2022, only. Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Joulu 202244min

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll find out that kids are killing themselves more often and at younger ages. Suicide prevention expert Dr. Mark Goulston joins the show to discuss the very real and very urgent topics of youth mental health and suicide—from pre-teens to teens to young adults. These issues concern everyone, not only families, educators or professionals who connect with young people. Here’s why:Suicide shows up in the top three causes of death in young people between the ages of 10-24, according to 2020 stats from the Centers for Disease Control and Prevention (CDC) WISQARS Leading Causes of Death Reports.Young people are hurting. The National Alliance on Mental Illness reports that nearly 20% of high school students say they’ve had serious thoughts of suicide and 9% have made an attempt to take their lives. Dr. Mark explains that many young people struggling mentally and emotionally feel like they're a burden to everyone. And they don’t have confidence that parents can help them feel better. You’ll learn a lot during this conversation, such as:factors driving teen mental health issues and teen suicide.what’s going on in the teen brain from a developmental perspective that leads them to think that death is a preferable alternative to working through life situations.signs or red flags that a teen is struggling. how parents and adults often can diminish or dismiss teens’ emotions, situations with friends or love relationships.what emotional intelligence skills are most useful for parents/adults to better understand teens.how to talk to teens—whether you’re a parent or a caring adult in a teen’s life.how to improve listening in a culture dominated by tech.how to listen to teens and help them realize and understand their emotions—without cutting them off, interrupting them, or jumping to advice and solutions.when to seek professional intervention.More about Dr. Mark Goulston: He's a retired psychiatrist, former UCLA professor of psychiatry and former FBI and police hostage negotiation trainer. He recently received the “Shine the Light Media Award” from the Los Angeles County Medical Association for bringing attention to teen mental health and suicide. He’s the author or co-author of nine books: “Just Listen: Discover the Secret to Getting Through to Absolutely Anyone,” ranks in the 15 Best Communication Skills Books of All Time.Watch this episode on YouTube!Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterGet Fit in Five Minutes: https://www.carolbike.com, use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial.Business Growth With SEO: https://www.stephanspencer.com, get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Joulu 20221h 1min

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about a new holistic framework for self-healing and how to heal yourself with prompts, tools and actionable tips.Using the tenants of holistic psychology, Nicole LePera, Ph.D., created a different way to reach people and equip them with the tools necessary to heal themselves. Holistic psychology focuses on the mind, body, and soul in the service of rebalancing the body and nervous system and healing unresolved emotional wounds. It’s all about a daily practice of creating your own wellness by:seeing yourself from a new perspective,breaking negative patterns, healing from your past, andcreating your conscious self.Nicole, the author of the New York Times Bestselling Book “How to Do the Work: Recognize Your Patterns, Heal from Your Past, and Create Your Self,” builds on that theme and goes even deeper with her newly published “How to Meet Your Self: The Workbook for Self-Discovery” workbook.In this conversation, you’ll find out how to:objectively and compassionately observe the physical, mental, and emotional patterns that keep you stuck.deep dive into your ego, trauma and emotions so you can safely do the inner work that can transform your outer world.change ingrained beliefs and habits so you can move toward realizing your authentic self. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProTest Your Own Biology: https://knowinglabs.com/dave, use code dave to save 20% off any test kitSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Joulu 202248min

IN THIS EPISODE OF THE HUMAN UPGRADE™… Dan Buettner joins the show to talk about the origins and food foundations of Blue Zones. He discusses how they were discovered, what makes them different, and what’s changed for people living there over the past few decades. And the big question—is it still possible to live to 100?Dan, an explorer, National Geographic Fellow, award-winning journalist and producer, and photographer, has studied and written extensively about the five places in the world—dubbed Blue Zones—where people live the longest, healthiest, and often happiest lives. He’s partnered with epidemiologists, anthropologists, medical researchers, demographers, and statisticians to take a data-based approach to everything from genetics to census data.Combining this intensive research with cultural immersion, Dan’s brought out aspects of Blue Zones lifestyles—like food and social connection—that form a foundation for human life quality and longevity. He’s the bestselling author of a series of Blue Zone books.In Dan’s latest Blue Zones adventure, he took a road trip across the United States to explore food and communities. He found that pockets of Blue Zones do exist throughout the U.S. He talked to heritage cooks passing on recipes to younger generations. He uncovered the traditional roots of plant-forward cuisine in the United States and presents both traditional and revolutionary ideas in vegetarian food in his newest book, “The Blue Zones American Kitchen: 100 Recipes to Live to 100.” Stunning photography and recipes show the vitality of both food and people from five distinct areas: Indigenous, Native & Early American, African American, Latin American, Asian American and Regional and Contemporary American.Dan also dug deep into the country’s food history and brings to light the dramatic changes in food processing, regulation, government intervention, and leadership choices that have influenced food supply. He combed through 60 oral histories, scientific reports and academic papers to reconstruct traditional American diets. In “The Blue Zones American Kitchen,” you’ll find out why the 1970s were the worst decade for America’s food environment. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Upgrade Your Air Quality: https://hypoair.com/Dave/Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount. Learn more: Magnesium: The Master Mineral That Conquers Stress – BiOptimizers – #669See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Joulu 202249min

(ZBiotics sponsored this episode.)IN THIS EPISODE OF THE HUMAN UPGRADE™… you'll find out how to counter the sometimes rough morning after you have alcohol. The key is a new genetically engineered pre-alcohol probiotic drink. Great timing as you head into the holiday season of celebrations.Zack Abbott, CEO & co-founder of ZBiotics, joins this 1,000th episode of the podcast to talk about new discoveries in alcohol metabolism, genetic engineering and GMOs (used in a good way!), and the power of microbes.Ever wondered why you feel like crap the morning after drinking alcohol? The cause is a byproduct called acetaldehyde that forms in your gut when you drink alcohol. The ZBiotics Pre-Alcohol Probiotic Drink breaks down acetaldehyde while you drink so you can feel better the morning after.Prior to starting ZBiotics, Zack, who has a Ph.D. in microbiology and immunology, worked in clinical trial design, researched HIV vaccines, and pursued novel antibiotics in both academia and industry.He invented the ZBiotics proprietary technology using genetic engineering to develop new probiotics—ones with specific, unique abilities to improve your daily life. He’s proving through science that incredible things can be done with GMOs and genetically engineered microbes.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://zbiotics.com/dave and use code "dave" to save 15%.Watch this episode on YouTube! Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterHarness Cold to Improve Health & Performance: https://www.cryobuilt.comBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Marras 202255min

In this Episode of The Human Upgrade™...​Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Sperm that swim together increase their chances of fertilizationLate-night eating is worse than you thoughtMetabolic markers can be measured through your sweatEye movements during REM sleep could delete unwanted memoriesEPISODE SPONSOR: Humic & fulvic minerals provide critical cellular support. Go to https://www.beamminerals.com and use code DAVE20 to get 20% off. Learn more: How Minerals Combat Glyphosate’s Harm – Caroline Alan – #948.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Marras 20228min

Timeline Nutrition sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria. Urolithin A activates mitophagy and renews your mitochondria. “It takes all the cellular garbage that has been accumulating over the aging process,” Dr. Singh explains. “It revs it up, so it recharges. And so now, you're cleaning your metabolic waste products much more efficiently and they become the building blocks. This is mitochondrial biogenesis, and that means newer, healthy mitochondria coming in.”This new conversation takes an exciting turn into immunity and your immune system’s two lines of defense: innate and adaptive. You’ll learn:how inflammation plus aging (AKA inflammaging) contributes to a weakened immune system and a growing incidence of cancer as you age;how inflammaging and cancer are connected to mitochondrial dysfunction specifically during the aging process; andhow to approach your immune health differently with this new knowledge.A new study recently published in Immunity looks at how immune cells fight cancer better with a focus on immune modulation, immune cell exhaustion and immune responses. “A lot of urolithin A is anti-inflammatory, but a lot of it is immune modulation," Dr. Singh says. "So, it takes a rewiring of the immune system and makes it more conducive to stopping harmful immune responses.”Watch this episode on YouTube!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: To learn more about the benefits of urolithin A, go to https://www.timelinenutrition.com and use code UPGRADE10 to get 10% off the plan of your choice. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount. Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

22 Marras 202250min

IN THIS EPISODE OF THE HUMAN UPGRADE™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn:how your microbiome continually evolves and why that matters to the state of your gut and body functions.how to strengthen the antiviral defenses located in your gut.why your body’s own ability “to resist, heal, and recover from viruses is vastly superior” to pharmaceuticals.what to do before taking antibiotics to protect your gut, as well as what you can do to rehab your microbiome after antibiotic use.“Being on the winning team when battling viruses isn’t because of good luck, or coincidence, or variations in viral virulence,” Dr. Chutkan explains in her newest book, “The Anti-Viral Gut: Tackling Pathogens from the Inside Out.” "It’s due to differences in us, the hosts, and our defenses, and those differences are what determine your outcome. Put another way: it’s less about the potency of the pathogen and more about the health of the host.”Dr. Chutkan is a Yale- and Columbia-educated integrative gastroenterologist who’s been advancing knowledge and education about gut health for decades. Nearly 20 years ago she founded the Digestive Center for Wellness to help people get to the root issue of their digestive issues and improve their gut health. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Brain Training with Sound & Vibration: Change unwanted behaviors, reduce negative self-talk, and enhance motivation and performance. Go to www.braintap.com/dave to get 30% offMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount.Get Fit in Five Minutes: https://www.carolbike.com, use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Marras 20221h 17min