Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Moderator: Jean-Marc Burgunder (Guemligen, Switzerland)Guest: Sandrine Humbert (Paris, France)In this week's episode, Burgunder and Humbert discuss the intriguing phenomenon of somatic expansion—the further increase of CAG repeat numbers in the gene involved in Huntington’s disease, particularly in the striatum. They explore the molecular mechanisms behind this process, as addressed in two recent research papers.Please find here the papers discussed in this episode: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s diseaseand Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

Jaksot(187)

Ep. 131: Assessment of prognosis in TBI

Ep. 131: Assessment of prognosis in TBI

Moderator: Luca Sebastianelli (Vipiteno, Italy) Guest: Olli Tenovuo (Turku, Finland) In this episode Luca Sebastianelli and Olli Tenovuo discuss the many factors that influence the recovery and thus...

19 Tammi 202526min

Ep. 130: The juvenile brain

Ep. 130: The juvenile brain

EAN Moderator: Jana Midelfart Hoff (Bergen, Norway) Guest: Marte Roa Syversen (Drammen, Norway) In this week’s episode Jana Midelfart Hoff and Marte Roa Syversen discuss what happens in the brain w...

12 Tammi 202526min

Ep. 129: From then to now: Neurology through the years

Ep. 129: From then to now: Neurology through the years

EAN moderator: Thomas Berger (Vienna, Austria) Guest: Gereon Fink (Cologne, Germany) In this first eanCast episode of 2025, Thomas Berger and Gereon Fink discuss how dramatically Neurology has chang...

5 Tammi 202532min

Ep. 128: Inclusive Communication with sexual and gender minorities in Neurology

Ep. 128: Inclusive Communication with sexual and gender minorities in Neurology

Moderator: Francesco Pasini (Milano, Italy) Cianán Russell (Brussels, Belgium) In this last episode of the year, Francesco Pasini and Cianán Russel talk about inclusive communication with sexual and...

29 Joulu 202422min

Ep. 127: Sex and gender differences in Parkinson’s disease

Ep. 127: Sex and gender differences in Parkinson’s disease

Moderator: Vanessa Carvalho (Lisbon, Portugal) Guest: Angelo Antonini (Padua, Italy) This week Vanessa Carvalho hosts expert Angelo Antonini as they review not only prevalence but also sex and gende...

22 Joulu 202426min

Ep. 126: Sex and gender differences in Alzheimer’s disease

Ep. 126: Sex and gender differences in Alzheimer’s disease

Moderator: Luca Cuffaro (Milano, Italy) Guest: Julie Novakova Martinkova (Prague, Czechia) In this episode, Dr. Luca Cuffaro and Dr. Julie Novakova Martinkova discuss sex and gender differences in A...

15 Joulu 202424min

Ep. 125: Navigating Gender Differences in Neurology Careers

Ep. 125: Navigating Gender Differences in Neurology Careers

Moderator: Alice Accorroni (Geneva, Switzerland) Guest: Marianne de Visser (Amsterdam, Netherlands) In this week’s episode Alice Accorroni and Marianne de Visser discuss the multifaceted impact of ge...

8 Joulu 202424min

Ep. 124: Insights into the EAN Leadership Programme

Ep. 124: Insights into the EAN Leadership Programme

Ean Moderator: Anja Sander (Vienna, Austria) Guest: Peter Dedeken (Sint-Katelijne-Waver, Belgium) Guest: Vanessa Carvalho (Lisbon, Portugal) This week we are happy to share an episode about the EAN L...

1 Joulu 202425min

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