Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease
eanCast: Weekly Neurology6 Huhti 2025

Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Moderator: Jean-Marc Burgunder (Guemligen, Switzerland)Guest: Sandrine Humbert (Paris, France)In this week's episode, Burgunder and Humbert discuss the intriguing phenomenon of somatic expansion—the further increase of CAG repeat numbers in the gene involved in Huntington’s disease, particularly in the striatum. They explore the molecular mechanisms behind this process, as addressed in two recent research papers.Please find here the papers discussed in this episode: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s diseaseand Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

Jaksot(187)

Ep. 123: News on the risk of malformations and developmental impairment among the offspring of male patients under antiseizure medication​

Ep. 123: News on the risk of malformations and developmental impairment among the offspring of male patients under antiseizure medication​

Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany) Guest: Jakob Christensen (Aarhus, Denmark) In this last November episode Bernhard Steinhoff and Jakob Christensen give an update on new data con...

24 Marras 202416min

Ep. 122: News on the risk of malformations and developmental impairment among the offspring of female patients under antiseizure medication

Ep. 122: News on the risk of malformations and developmental impairment among the offspring of female patients under antiseizure medication

Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany) Guest: Jakob Christensen (Aarhus, Denmark) This week Bernhard Steinhoff talks with Jakob Christensen about the latest news on the risk of antisei...

17 Marras 202418min

Ep. 121: New developments concerning neurostimulation in epilepsy​

Ep. 121: New developments concerning neurostimulation in epilepsy​

Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany) Guest: Kristl Vonck (Gent, Belgium) In this episode, Bernhard Steinhoff speaks with expert Kristl Vonck on the latest advancements in neurostimula...

10 Marras 202421min

Ep. 120: New developments of long- and ultralong EEG in epileptology​

Ep. 120: New developments of long- and ultralong EEG in epileptology​

Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany) Guest: Andreas Schulze-Bonhage (Freiburg, Germany) In this episode Bernhard J. Steinhoff and Andreas Schulze-Bonhage discuss the new fascinating ...

3 Marras 202420min

Ep. 119: Phase 2 HOPE clinical trial results

Ep. 119: Phase 2 HOPE clinical trial results

Moderator: Theodoros M. Mavridis (Dublin, Ireland) Guest: Messoud Ashina (Glostrup, Denmark) In this episode Theodoros M. Mavridis and Messoud Ashina delve into the findings of the Phase 2 HOPE clini...

27 Loka 202423min

Ep. 118: Rare causes of myelopathy

Ep. 118: Rare causes of myelopathy

Moderator: Roland Wiest (Bern, Switzerland) Guest: Randolf Klingebiel (Bielefeld, Germany) In this episode, Roland Wiest and Randolf Klingebiel explore rare causes of myelopathy, a challenging condit...

20 Loka 202423min

Ep. 117: Imaging of spinal cord ischemia

Ep. 117: Imaging of spinal cord ischemia

Moderator: Raphael Wurm (Vienna, Austria) Guest: Majda Thurnher (Vienna, Austria) For this episode, Raphaela Wurm welcomes Majda Thurnher to dive into the challenges and joys of diagnosing spinal cor...

13 Loka 202422min

Ep. 116: ​Indications and pitfalls of spinal imaging​

Ep. 116: ​Indications and pitfalls of spinal imaging​

Moderator: Raphael Wurm (Vienna, Austria) Guest: Dr. Wolfgang Marik (Vienna, Austria) In this episode, Raphael Wurm and Wolfgang Marik explore key neuroimaging techniques for the spine, focusing on...

6 Loka 202422min

Suosittua kategoriassa Tiede

rss-mita-tulisi-tietaa
rss-poliisin-mieli
tiedekulma-podcast
rss-duodecim-lehti
docemilia
rss-lihavuudesta-podcast
utelias-mieli
radio-antro
rss-sosiopodi
sotataidon-ytimessa
mielipaivakirja
filocast-filosofian-perusteet
rss-laakaripodi
rss-radplus
rss-opeklubi
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita