198 | Nick Lane on Powering Biology

The origin of life here on Earth was an important and fascinating event, but it was also a long time ago and hasn't left many pieces of direct evidence concerning what actually happened. One set of clues we have comes from processes in current living organisms, especially those processes that seem extremely common. The Krebs cycle, the sequence of reactions that functions as a pathway for energy distribution in aerobic organisms, is such an example. I talk with biochemist about the importance of the Krebs cycle to contemporary biology, as well as its possible significance in understanding the origin of life.

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Nick Lane received his PhD from the Royal Free Hospital Medical School. He is currently a professor of Evolutionary Biochemistry at University College London. He was a founding member of the UCL Consortium for Mitochondrial Research, and is Co-Director of the UCL Centre for Life's Origin and Evolution. He was awarded the 2009 UCL Provost's Venture Research Prize, the 2011 BMC Research Award for Genetics, Genomics, Bioinformatics and Evolution, the 2015 Biochemical Society Award, and the 2016 Royal Society Michael Faraday Prize and Lecture. His new book is Transformer: The Deep Chemistry of Life and Death.


Jaksot(416)

321 | David Tong on Open Questions in Quantum Field Theory

321 | David Tong on Open Questions in Quantum Field Theory

Quantum field theory is the basis for our most successful theories of fundamental physics. And yet, there are things we don't understand about it. Some of these puzzles are relatively well-known, whil...

14 Heinä 20251h 19min

AMA | July 2025

AMA | July 2025

Welcome to the July 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

7 Heinä 20254h 3min

320 | Solo: Complexity and the Universe

320 | Solo: Complexity and the Universe

Our universe started out looking very simple: hot, dense, smooth, rapidly expanding. According to our best current model, it will end up looking simple once again: cold, dark, empty. It's in between -...

30 Kesä 20252h 14min

319 | Bryan Van Norden on Philosophy From the Rest of the World

319 | Bryan Van Norden on Philosophy From the Rest of the World

It is common to refer to philosophy as "a series of footnotes to Plato." But in the original quote, Alfred North Whitehead was more careful: he limited his characterization to "the European philosophi...

23 Kesä 20251h 12min

318 | Edward Miguel on the Developing Practice of Development Economics

318 | Edward Miguel on the Developing Practice of Development Economics

Economics is seeing an upsurge in the importance of controlled, reproducible empirical studies. One area where this has had a great impact is on development economics, which studies the economies of l...

16 Kesä 20251h 20min

317 | Nicole Rust on Why Neuroscience Hasn't Solved Brain Disorders

317 | Nicole Rust on Why Neuroscience Hasn't Solved Brain Disorders

The human brain is extremely complicated, but decades of careful neuroscientific research have revealed quite a bit about how it works, including how certain genes affect particular brain behaviors. N...

9 Kesä 20251h 14min

AMA | June 2025

AMA | June 2025

Welcome to the June 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

2 Kesä 20253h 23min

316 | Niayesh Afshordi and Phil Halper

316 | Niayesh Afshordi and Phil Halper

Einstein's general theory of relativity, plus some reasonable assumptions about the universe and what it's made of, has a remarkable implication: that as we trace cosmic evolution into the far past, w...

26 Touko 20251h 28min

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