Julia Mayerle on the validation of plasma multimetabolite signatures for patients at risk of or with suspected pancreatic ductal adenocarcinoma

Julia Mayerle on the validation of plasma multimetabolite signatures for patients at risk of or with suspected pancreatic ductal adenocarcinoma

Can a multi-metabolite blood test improve early pancreatic cancer detection? We spoke to Julia Mayerle about the METAPAC study, which sought to validate the ability of plasma metabolic signatures to find resectable tumors and reduce unnecessary invasive procedures in high-risk patients.

Read the full article:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00056-1/fulltext?dgcid=buzzsprout_icw_podcast_June_25_langas

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The Lancet Gastroenterology & Hepatology in conversation with... is part of the Lancet Group podcast offering.

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

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Jaksot(49)

Frank Ruemmele on a trial of cyclic exclusive enteral nutrition versus partial enteral nutrition to maintain remission in paediatric Crohn's disease

Frank Ruemmele on a trial of cyclic exclusive enteral nutrition versus partial enteral nutrition to maintain remission in paediatric Crohn's disease

In children with Crohn’s disease who achieve remission through exclusive enteral nutrition, what's the optimal dietary therapy to maintain remission without the use of medication or surgery? Frank Rue...

13 Elo 22min

Aleksander Krag on the utility of PEth for subclassifying individuals at risk of steatotic liver disease

Aleksander Krag on the utility of PEth for subclassifying individuals at risk of steatotic liver disease

Steatotic liver disease labels hinge on alcohol intake, but self-report is often inaccurate. In this episode, Aleksander Krag (Odense University Hospital) discusses a large Danish study using phosphat...

23 Helmi 20min

Dina Kao on a trial of lyophilised sterile faecal filtrate versus lyophilised conventional donor stool for recurrent Clostridiodes difficile infection

Dina Kao on a trial of lyophilised sterile faecal filtrate versus lyophilised conventional donor stool for recurrent Clostridiodes difficile infection

Can bacteria-free, sterile faecal filtrate match conventional faecal microbiota transplantation for recurrent C difficile infection? Dina Kao (University of Alberta) unpacks a landmark multicentre tri...

28 Marras 202515min

Premysl Bercik on a double-blind crossover trial of gluten and wheat in IBS

Premysl Bercik on a double-blind crossover trial of gluten and wheat in IBS

Do wheat or gluten trigger IBS symptoms?  We spoke to Premysl Bercik about a randomised, double-blind, sham-controlled crossover trial that challenged adults with IBS—who reported benefit from a glute...

20 Marras 202516min

Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis

Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis

How does acute kidney injury presentation and management differ globally for patients hospitalised with cirrhosis?  We spoke to Salvatore Piano, corresponding author of the landmark International Club...

9 Huhti 202519min

John Chia on the ASCOLT trial of adjuvant aspirin for colorectal cancer

John Chia on the ASCOLT trial of adjuvant aspirin for colorectal cancer

John Chia discusses the results of the ASCOLT trial, which explored the effect of aspirin after completion of standard adjuvant therapy for patients with colorectal cancer. Read the full article: http...

6 Maalis 202513min

Hannes Hagström on screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes

Hannes Hagström on screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes

Hannes Hagström discusses a study investigating the feasibility of screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes. Read the full article: https://www.t...

10 Tammi 202521min

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