Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson
Huberman Lab24 Heinä 2025

Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson

In this Huberman Lab Essentials episode, my guest is Dr. Matthew Johnson, PhD, a senior researcher for the Center of Excellence for Psilocybin Research and Treatment at Sheppard Pratt’s Institute for Advanced Diagnostics and Therapeutics. We explore the science and therapeutic potential of psychedelic medicine, including psilocybin, MDMA and LSD. We discuss how these substances can profoundly alter perception and self-identity, providing long-lasting relief from depression, addiction and trauma when used in controlled clinical settings. We also discuss microdosing and emerging research on psychedelics’ potential to support recovery from neurological injuries. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman BetterHelp: https://betterhelp.com/huberman Timestamps 00:00:00 Matthew Johnson; Psychedelics 00:01:44 Different Classes of Psychedelics 00:04:33 Psychedelics & Altering Models 00:06:18 Sponsor: David 00:07:33 LSD, Psylocibin & Serotonin 00:09:55 Psychedelic Clinical Trials 00:13:40 Therapy, Trust, Psychedelics 00:16:47 Letting Go & Psychedelic Experience, Self-Representation, Lasting Changes 00:22:31 Sponsors: AG1 & BetterHelp 00:25:26 MDMA, Dopamine & Serotonin; Bad Trips & Transcendental Experience 00:28:49 Dangers of Psychedelics 00:31:11 Microdosing Psychedelics, Antidepressant 00:35:27 Head Injuries, Psychedelics, Depression 00:38:29 Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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Unlearn Negative Thoughts & Behaviors Patterns | Dr. Alok Kanojia

Unlearn Negative Thoughts & Behaviors Patterns | Dr. Alok Kanojia

Dr. Alok Kanojia, MD, MPH ("Dr. K"), is a Harvard-trained psychiatrist and expert in both Eastern and Western medicine to improve mental health. He explains tools for unlearning maladaptive thoughts a...

2 Maalis 3h 8min

Essentials: Using Light to Optimize Health

Essentials: Using Light to Optimize Health

In this Huberman Lab Essentials episode, I explore how different wavelengths of light affect the human body and how light exposure can improve sleep quality, mood and daytime alertness while supportin...

26 Helmi 42min

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

Dr. Tony Wyss-Coray, PhD, is a professor of neurology at Stanford School of Medicine and Director of the Phil and Penny Knight Initiative for Brain Resilience who is discovering factors present in you...

23 Helmi 1h 59min

Essentials: Optimize Your Exercise Program with Science-Based Tools | Jeff Cavaliere

Essentials: Optimize Your Exercise Program with Science-Based Tools | Jeff Cavaliere

In this Huberman Lab Essentials episode, my guest is Jeff Cavaliere, MSPT, CSCS, a physical therapist, strength coach and the founder of ATHLEAN-X, an online training platform. We explain the foundat...

19 Helmi 40min

The Most Effective Weight Training, Cardio & Nutrition for Women | Dr. Lauren Colenso-Semple

The Most Effective Weight Training, Cardio & Nutrition for Women | Dr. Lauren Colenso-Semple

Dr. Lauren Colenso-Semple, PhD, is an expert in the science of strength and muscle building and nutrition. She explains the most effective resistance and cardiovascular training programs for women and...

16 Helmi 2h 32min

Essentials: The Science of Love, Desire & Attachment

Essentials: The Science of Love, Desire & Attachment

In this Huberman Lab Essentials episode, I explore the psychology and biology of desire, love and attachment. I explain how childhood attachment styles can shape adult romantic relationships and how t...

12 Helmi 39min

How Genes Shape Your Risk Taking & Morals | Dr. Kathryn Paige Harden

How Genes Shape Your Risk Taking & Morals | Dr. Kathryn Paige Harden

Dr. Kathryn Paige Harden, PhD, is a psychologist, behavioral geneticist and professor of psychology at the University of Texas at Austin. We discuss how genes interact with your upbringing to shape yo...

9 Helmi 2h 42min

Essentials: The Science & Practice of Movement | Ido Portal

Essentials: The Science & Practice of Movement | Ido Portal

In this Huberman Lab Essentials episode, my guest is Ido Portal, a movement coach and world expert on human movement. We explore the science and practice of movement, including how the nervous syste...

5 Helmi 38min

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