Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson
Huberman Lab24 Heinä 2025

Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson

In this Huberman Lab Essentials episode, my guest is Dr. Matthew Johnson, PhD, a senior researcher for the Center of Excellence for Psilocybin Research and Treatment at Sheppard Pratt’s Institute for Advanced Diagnostics and Therapeutics. We explore the science and therapeutic potential of psychedelic medicine, including psilocybin, MDMA and LSD. We discuss how these substances can profoundly alter perception and self-identity, providing long-lasting relief from depression, addiction and trauma when used in controlled clinical settings. We also discuss microdosing and emerging research on psychedelics’ potential to support recovery from neurological injuries. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman BetterHelp: https://betterhelp.com/huberman Timestamps 00:00:00 Matthew Johnson; Psychedelics 00:01:44 Different Classes of Psychedelics 00:04:33 Psychedelics & Altering Models 00:06:18 Sponsor: David 00:07:33 LSD, Psylocibin & Serotonin 00:09:55 Psychedelic Clinical Trials 00:13:40 Therapy, Trust, Psychedelics 00:16:47 Letting Go & Psychedelic Experience, Self-Representation, Lasting Changes 00:22:31 Sponsors: AG1 & BetterHelp 00:25:26 MDMA, Dopamine & Serotonin; Bad Trips & Transcendental Experience 00:28:49 Dangers of Psychedelics 00:31:11 Microdosing Psychedelics, Antidepressant 00:35:27 Head Injuries, Psychedelics, Depression 00:38:29 Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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Best Ways to Build Better Habits & Break Bad Ones | James Clear

Best Ways to Build Better Habits & Break Bad Ones | James Clear

James Clear is an expert on behavioral change and habits and the author of the bestselling book Atomic Habits. We discuss the best ways to build new healthy habits and end bad ones without relying on ...

5 Tammi 2h 35min

Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

In this Huberman Lab Essentials episode, my guest is Dr. Rhonda Patrick, PhD, a biomedical scientist and a leading health educator focused on nutrition, aging and general health. We discuss four key ...

1 Tammi 40min

Defining Healthy Masculinity & How to Build It | Terry Real

Defining Healthy Masculinity & How to Build It | Terry Real

Terry Real is a therapist and best-selling author expert on male emotional health and how men can build the skills for healthy relating to others: in relationships, work, friendships and to themselves...

29 Joulu 20252h 50min

Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

In this Huberman Lab Essentials episode, my guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improv...

25 Joulu 202542min

Transform Pain & Trauma Into Creative Expression | David Choe

Transform Pain & Trauma Into Creative Expression | David Choe

David Choe is a world-renowned artist, writer, podcaster and TV host. He tells how as a child, he was made to believe he was destined for greatness but also that he was a complete disgrace, leading hi...

22 Joulu 20253h 54min

Essentials: How to Set & Achieve Goals

Essentials: How to Set & Achieve Goals

In this Huberman Lab Essentials episode, I explain how to use science-based tools to better set and achieve goals. I discuss the neuroscience of goal pursuit and how dopamine and visual attention sh...

18 Joulu 202537min

Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains ...

15 Joulu 20253h 17min

Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

In this Huberman Lab Essentials episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University. We discuss how microbes in our gut impact our menta...

11 Joulu 202539min

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