#615: Dr. Andrew Weil — The 4-7-8 Breath Method, Cannabis, The Uses of Coca Leaf, Rehabilitating Demonized Plants, Kava for Anxiety, Lessons from Wade Davis, The Psychedelic Renaissance, How to Emerge from Depression, Tales from 50+ Visits to Japan, Matcha Benefits, and More

#615: Dr. Andrew Weil — The 4-7-8 Breath Method, Cannabis, The Uses of Coca Leaf, Rehabilitating Demonized Plants, Kava for Anxiety, Lessons from Wade Davis, The Psychedelic Renaissance, How to Emerge from Depression, Tales from 50+ Visits to Japan, Matcha Benefits, and More

Dr. Andrew Weil — The 4-7-8 Breath Method, Cannabis, The Uses of Coca Leaf, Rehabilitating Demonized Plants, Kava for Anxiety, Lessons from Wade Davis, The Psychedelic Renaissance, How to Emerge from Depression, Tales from 50+ Visits to Japan, Matcha Benefits, and More | Brought to you by Levels real-time feedback on how diet impacts your health, Athletic Greens all-in-one nutritional supplement, and LMNT electrolyte supplement. More on all three below.

Andrew Weil, MD (@DrWeil) is a pioneer in the field of integrative medicine. He has been named one of the 100 most influential people in the world by Time magazine.

Dr. Weil received a degree in biology (botany) from Harvard College in 1964 and an MD from Harvard Medical School in 1968. From 1971 to 1975, as a fellow of the Institute of Current World Affairs, Dr. Weil traveled widely in North and South America and Africa collecting information on drug use in other cultures, medicinal plants, and alternative methods of treating disease. From 1971 to 1984 he was on the research staff of the Harvard Botanical Museum and conducted investigations of medicinal and psychoactive plants.

Dr. Weil is the founder and director of the Andrew Weil Center for Integrative Medicine at the University of Arizona, where he also holds the Lovell-Jones Endowed Chair in Integrative Medicine and is Clinical Professor of Medicine and Professor of Public Health. Through its fellowship and Integrative Medicine in Residency curricula, the Center is now training doctors and nurse practitioners around the world.

A New York Times best-selling author, Dr. Weil has written 15 books on health and well-being, including Mind Over Meds; Fast Food, Good Food; True Food; Spontaneous Happiness; Healthy Aging; and Eight Weeks to Optimum Health. He is also co-founder of the restaurant chain True Food Kitchen and co-founder of Matcha.com, which offers extremely high-quality matcha that is difficult to find outside of Japan.

Please enjoy!

This episode is brought to you by Levels! I wrote about the health benefits of using continuous glucose monitors (CGMs) more than ten years ago in The 4-Hour Body. At the time, CGMs were primitive and hard to use. Levels has now made this technology, and the unique insights that come from it, easy and available to everyone. Levels is making glucose monitoring simple, helping you see how food affects your health through real-time feedback. I started tracking my glucose years ago to learn more about what I should and shouldn’t be eating (including quantities, time of day, etc.), based on objective data from my own, unique physiology. Keeping my blood sugar stable is critical to my daily and long-term health and performance goals. Furthermore, poor glucose control is associated with a number of chronic conditions like diabetes, Alzheimer’s disease, heart disease, and obesity. It’s important.

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This episode is also brought to you by Athletic Greens. I get asked all the time, “If you could use only one supplement, what would it be?” My answer is usually AG1 by Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system.

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[07:56] What is the 4-7-8 breath?

[10:15] As an early advocate, what is Dr. Weil’s current relationship with cannabis?

[11:28] Overcoming the stigma of coca leaves to realize their medical benefits.

[14:17] What is The Beneficial Plants Research Association?

[16:30] Thoughts on kava and its effect on sleep quality.

[19:49] Where to learn more about kratom and mitragynine.

[20:51] Andrew’s experience with Bufo alvarius.

[22:05] Why Andrew and Wade Davis are reviving The Beneficial Plants Research Association.

[25:27] Andrew recounts a Richard Evans Schultes story.

[27:13] Andrew’s brief career as a letter-writing prankster.

[29:06] Covering the first wave of psychedelic research at Harvard.

[34:15] The positives and negatives of psychedelics going mainstream.

[36:11] Taxonomy and the origin of Psilocybe weilii.

[37:58] How did Andrew emerge from dysthymia in his early fifties?

[39:54] Lessons learned on visits to Japan and Okinawa.

[45:19] Health benefits of fermented turmeric and matcha tea.

[49:50] How L-theanine modifies the effects of caffeine.

[52:19] How Andrew’s parents encouraged him to always be curious (but careful).

[55:36] Getting older and future plans.

[58:11] Why you should check out The Andrew Weil Center for Integrative Medicine.

[58:54] What Andrew believes gets missed most by current psychedelic exploration.

[1:02:00] Parting thoughts.

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For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.

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#839: Dr. Fei-Fei Li, The Godmother of AI — Asking Audacious Questions, Civilizational Technology, and Finding Your North Star

#839: Dr. Fei-Fei Li, The Godmother of AI — Asking Audacious Questions, Civilizational Technology, and Finding Your North Star

Dr. Fei-Fei Li (@drfeifei) is the inaugural Sequoia Professor in the Computer Science Department at Stanford University, a founding co-director of Stanford’s Human-Centered AI Institute, and the co-fo...

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#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello

#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello

Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)!This episode is brought to you by:Qlosi prescription eye drop used to treat age-related...

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#837: How to Simplify Your Life in 2026 — New Tips from Derek Sivers, Seth Godin, and Martha Beck

#837: How to Simplify Your Life in 2026 — New Tips from Derek Sivers, Seth Godin, and Martha Beck

As we head into the new year, many of us feel like we’re drowning in invisible complexity. So I wanted to hit pause and ask a simple question: What are 1-3 decisions that could dramatically simplify m...

26 Marras 202532min

#836: The 4-Hour Workweek Principles — 13 Mistakes to Avoid, The Art of Mini-Retirements, and Navigating the Dizziness of Freedom

#836: The 4-Hour Workweek Principles — 13 Mistakes to Avoid, The Art of Mini-Retirements, and Navigating the Dizziness of Freedom

This time around, we have a bit of a different format, featuring the book that started it all for me, The 4-Hour Workweek. Readers and listeners often ask me what I would change or update, but an equa...

19 Marras 20251h 37min

#835: Ben Patrick (KneesOverToesGuy) — 20-Minute Workouts That Produce Wild Results, From Chronic Knee Pain to Dunking Basketballs, Lessons from Charles Poliquin, Bulletproofing the Lower Body, and More

#835: Ben Patrick (KneesOverToesGuy) — 20-Minute Workouts That Produce Wild Results, From Chronic Knee Pain to Dunking Basketballs, Lessons from Charles Poliquin, Bulletproofing the Lower Body, and More

Ben Patrick, better known as “Kneesovertoesguy” (@kneesovertoesguy), is the founder of Athletic Truth Group (ATG), an online and brick-and-mortar training system rooted in rehabilitative strength and ...

12 Marras 20251h 37min

#834: David Baszucki, Co-Founder of Roblox — The Path to 150M+ Daily Users, Critical Business Decisions, Ketogenic Therapy for Brain Health, Daily Routines, The Roblox Economy, and More

#834: David Baszucki, Co-Founder of Roblox — The Path to 150M+ Daily Users, Critical Business Decisions, Ketogenic Therapy for Brain Health, Daily Routines, The Roblox Economy, and More

David Baszucki is the founder and CEO of Roblox. TIME named Roblox one of the “100 Most Influential Companies,” and it has been recognized by Fast Company for innovation on their “Most Innovative Comp...

5 Marras 20251h 55min

#833: Jack Canfield — Selling 600+ Million Books, Success Principles, and How He Made The 4-Hour Workweek Happen

#833: Jack Canfield — Selling 600+ Million Books, Success Principles, and How He Made The 4-Hour Workweek Happen

Jack Canfield is the coauthor of more than two hundred books, including, The Success Principles™: How to Get from Where You Are to Where You Want to Be and the Chicken Soup for the Soul® series, which...

29 Loka 20251h 37min

#832: The Return of The Lion Tracker — Boyd Varty on The Wild Man Within, Nature’s Hidden Wisdom, and How to Feel Fully Alive

#832: The Return of The Lion Tracker — Boyd Varty on The Wild Man Within, Nature’s Hidden Wisdom, and How to Feel Fully Alive

Boyd Varty is the founder of Track Your Life, which offers a limited number of premium retreats in South Africa’s bushveld, and author of one of my favorite books, The Lion Tracker’s Guide to Life. As...

22 Loka 20252h 2min

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