#517: Agentic Al Programming with Python
Talk Python To Me22 Elo 2025

#517: Agentic Al Programming with Python

Agentic AI programming is what happens when coding assistants stop acting like autocomplete and start collaborating on real work. In this episode, we cut through the hype and incentives to define “agentic,” then get hands-on with how tools like Cursor, Claude Code, and LangChain actually behave inside an established codebase. Our guest, Matt Makai, now VP of Developer Relations at DigitalOcean, creator of Full Stack Python and Plushcap, shares hard-won tactics. We unpack what breaks, from brittle “generate a bunch of tests” requests to agents amplifying technical debt and uneven design patterns. Plus, we also discuss a sane git workflow for AI-sized diffs. You’ll hear practical Claude tips, why developers write more bugs when typing less, and where open source agents are headed. Hint: The destination is humans as editors of systems, not just typists of code.

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#36: Python IDEs with the PyCharm team

#36: Python IDEs with the PyCharm team

As a software developer, what's the most important application on your computer? If your answer is Microsoft Outlook, my heart goes out to you - stay strong! But for most of us, it's probably a toss u...

1 Joulu 201559min

#35: Turbogears and the future of Python web frameworks

#35: Turbogears and the future of Python web frameworks

Do you have a new web project coming up? Are you thinking of choosing Django or maybe Flask? Those are excellent frameworks, but you might also want to check out TurboGears.

24 Marras 20151h 1min

#34: Continuum: Scientific Python and The Business of Open Source

#34: Continuum: Scientific Python and The Business of Open Source

What if you built a product that dramatically improved how hundreds of free, open source Python libraries worked together, gave it to the world for free, and then built a thriving business on it? It's...

17 Marras 201559min

#33: OpenStack: Cloud computing built on Python

#33: OpenStack: Cloud computing built on Python

You've probably heard of Infrastructure-as-a-services (IaaS) cloud providers such as Amazon's AWS, with EC2 in particular, and to a lesser degree Microsoft's Azure cloud platform. But have you hear of...

10 Marras 201556min

#32: PyPy.js - PyPy Python in Your Browser

#32: PyPy.js - PyPy Python in Your Browser

Imagine a future where you are building that rich, client-side web app. You start by creating some backend services in Flask or Node, an HTML page, throw in a few divs and uls, and then you type [scri...

3 Marras 201559min

#31: Machine Learning with Python and scikit-learn

#31: Machine Learning with Python and scikit-learn

Machine learning allows computers to find hidden insights without being explicitly programmed where to look or what to look for. Thanks to the work of some dedicated developers, Python has one of the ...

27 Loka 201549min

#30: Python Community and Python at Dropbox

#30: Python Community and Python at Dropbox

What does it mean to be a leader in the Python community? Contributing to open source? Speaking at conferences? Starting the largest user group? Writing a book? Being a core contributor? The answer is...

20 Loka 201546min

#29: Python at the Large Hadron Collider and CERN

#29: Python at the Large Hadron Collider and CERN

The largest machine ever built is the Large Hadron Collider at CERN. It's primary goal was the discovery of the Higgs Boson: the fundamental particle which gives all objects mass. The LHC team of 1000...

13 Loka 201552min