#03 - Ron Krauss, M.D.: a deep dive into heart disease
The Peter Attia Drive2 Heinä 2018

#03 - Ron Krauss, M.D.: a deep dive into heart disease

Whenever I'm stumped on a patient case or in my thinking about lipids, Ron is one of the first people I turn to for insight. Ron is recognized globally for his research into lipidology and has worn many hats in his career, including clinician, lipidologist, nutrition, genetics, and drug research.

In this episode, we explore heart disease at its origins before diving into the highly discussed, largely misunderstood, role of LDL and inflammation in atherosclerosis. Ron also shares his insights on the evidence for and against statins and other lipid-lowering therapies. My hope is that both the curious patient and the physician can get a lot out of this episode by being more informed about dyslipidemia and the interventions used to reduce the risk of atherosclerotic disease. We covered a lot of ground on this critically important topic.

We discuss:

  • The pathogenesis of atherosclerosis [7:00];
  • How early atherosclerosis begins [12:40];
  • Ron's motivation for getting into lipidology [43:00];
  • How reading an article series in the NEJM in 1967 had a profound impact on him and his career [43:30];
  • How PCSK9 inhibitors work and why they may be under-utilized [47:00];
  • Mendelian randomization: nature's randomized trial [49:15];
  • The "battle" between particle size and particle number [52:00];
  • The use of statins [1:04:45];
  • The role of chronic inflammation in atherosclerosis [1:24:15];
  • Why niacin may have been unjustly dismissed as a therapeutic option [1:40:45];
  • The HDL paradox: why drugs that raise HDL-C seem to raise (or have little impact on) heart disease risk [1:43:00];
  • Lp(a) [1:47:45];
  • And more.

Learn more at www.PeterAttiaMD.com

Connect with Peter on Facebook | Twitter | Instagram

Jaksot(433)

#370 - AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — proven, promising, fuzzy, noise, or nonsense?

#370 - AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — proven, promising, fuzzy, noise, or nonsense?

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter revisits the "prove...

27 Loka 202517min

#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Rhonda Patrick is a scientist, health educator, and host of the Fo...

20 Loka 20251h 50min

#368 ‒ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

#368 ‒ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter David Allison is a world-renowned scientist and award-winning scie...

13 Loka 20251h 49min

#367 - Tylenol, pregnancy, and autism: What recent studies show and how to interpret the data

#367 - Tylenol, pregnancy, and autism: What recent studies show and how to interpret the data

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this special episode of The Drive, Peter addresses the recent h...

6 Loka 20251h 27min

#366 ‒ Transforming education with AI and an individualized, mastery-based education model | Joe Liemandt

#366 ‒ Transforming education with AI and an individualized, mastery-based education model | Joe Liemandt

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Joe Liemandt is a software entrepreneur turned education reformer ...

29 Syys 20251h 47min

#365 ‒ Training for longevity: A roundtable on building strength, preventing injury, meeting protein needs, guidance for women and youth athletes, and more | Gabrielle Lyon, Mike Boyle, Jeff Cavaliere

#365 ‒ Training for longevity: A roundtable on building strength, preventing injury, meeting protein needs, guidance for women and youth athletes, and more | Gabrielle Lyon, Mike Boyle, Jeff Cavaliere

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this special episode of The Drive, Peter hosts a strength and c...

22 Syys 20252h 15min

#364 – AMA #75: Diets: how to evaluate and implement any diet including keto, carnivore, vegan, Mediterranean, and more

#364 – AMA #75: Diets: how to evaluate and implement any diet including keto, carnivore, vegan, Mediterranean, and more

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter explores how to det...

15 Syys 202513min

#363 ‒ A new frontier in neurosurgery: restoring brain function with brain-computer interfaces, advancing glioblastoma care, and new hope for devastating brain diseases | Edward Chang, M.D.

#363 ‒ A new frontier in neurosurgery: restoring brain function with brain-computer interfaces, advancing glioblastoma care, and new hope for devastating brain diseases | Edward Chang, M.D.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Edward Chang is a neurosurgeon, scientist, and a pioneering leader...

8 Syys 20251h 53min

Suosittua kategoriassa Terveys ja hyvinvointi

unicast
tiedenaiset-podcast
psykopodiaa-podcast
voi-hyvin-meditaatiot-2
vakeva-elama-viisaampi-mieli-vahvempi-keho
rss-pitaisko-erota
rss-kuumilla-aalloilla
rss-narsisti
meditaatiot-suomeksi
selviytyjat-tarinoita-elamasta
rss-pt-paahtio
puhu-muru
junnut-pelissa
rss-nautinto
terapiassa
rss-uplevel-by-sonja-hannus
rss-en-saa-unta
rss-sanelunpurku-podcast
yes-girl
rss-fitissa-podcast