#22 - Tom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteins

#22 - Tom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteins

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part III, Peter and Tom dig into HDL, why "reverse cholesterol transport" is a lot more nuanced than what most of us are taught, lipid transport, apolipoproteins, and more. In addition, this episode highlights the complexity of HDL and a discussion about the CETP inhibitor trials.

We discuss:

  • Reverse cholesterol transport [1:40];
  • Lipid transportation, apolipoproteins, VLDL, IDL, and LDL particles [11:00];
  • Remnant lipoproteins and apoC-III [16:45];
  • Particles having sex: lipid exchange [28:00];
  • Cholesteryl Ester Transfer Protein (CETP) and CETP inhibitors [40:45];
  • 2006 CETP inhibitor trial: torcetrapib (Pfizer) [54:45];
  • 2012 CETP inhibitor trial: dalcetrapib (Hoffmann–La Roche) [56:15];
  • 2017 CETP inhibitor trials: evacetrapib (Eli Lilly) and anacetrapib (Merck) [58:00]; and
  • More.

Learn more at www.PeterAttiaMD.com

Connect with Peter on Facebook | Twitter | Instagram.

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#25 - Scott Harrison: transformation, finding meaning, and taking on the global water crisis

#25 - Scott Harrison: transformation, finding meaning, and taking on the global water crisis

We discuss: How Scott and Peter met [3:45]; Scott's tragic family story that shaped his life and altered his trajectory [8:00]; High school years, rebellion, and music [30:30]; Life as a club promote...

22 Loka 20182h 18min

#24 - Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more

#24 - Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject o...

19 Loka 20181h 29min

#23 - Tom Dayspring, M.D., FACP, FNLA  – Part IV of V: Statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brain

#23 - Tom Dayspring, M.D., FACP, FNLA – Part IV of V: Statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brain

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject o...

18 Loka 20182h

#21 - Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation

#21 - Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject o...

16 Loka 20181h 26min

#20 - Thomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology

#20 - Thomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject o...

15 Loka 20181h 14min

#19 - Dave Feldman: stress testing the lipid energy model

#19 - Dave Feldman: stress testing the lipid energy model

In this episode, Dave Feldman, discusses his journey from software engineer to n=1 experimenter, his experience with low-carbohydrate diets, and his hypothesis that cholesterol levels are influenced b...

8 Loka 20183h 10min

#18 - Richard Isaacson, M.D.: Alzheimer's prevention

#18 - Richard Isaacson, M.D.: Alzheimer's prevention

In this episode, Richard Isaacson, a neurologist and director of the Alzheimer's Prevention Clinic at Weill Cornell Medicine and NewYork-Presbyterian, discusses strategies for staving off Alzheimer's ...

1 Loka 20182h 24min

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