Asthma, COPD, Emphysema: The Smoking Connection Explained

Asthma, COPD, Emphysema: The Smoking Connection Explained

Every puff of cigarette smoke delivers toxic chemicals deep into your lungs—triggering a cascade of damage that most people don’t realise until it’s too late. Dr. Ferghal Armstrong dives into the devastating effects of smoking on lung health, from early symptoms like chronic cough to advanced stages of chronic obstructive pulmonary disease (COPD) and emphysema.You'll learn how cigarette smoke impacts the respiratory system, destroying protective cilia, paralysing the mucociliary escalator, and overwhelming the lungs' ability to repair themselves. Discover the difference between chronic bronchitis and emphysema, how they contribute to irreversible lung damage, and why many patients don’t get diagnosed until their breathlessness is severe.This video also explains the clinical side: how spirometry detects obstructive patterns, how CT scans reveal emphysematous changes, and why smoking cessation is the only proven way to slow disease progression. We cover genetic risk factors like alpha-1 antitrypsin deficiency, the dangers of secondhand and thirdhand smoke, and how smoking during pregnancy affects fetal lung development.Whether you're a healthcare student, medical professional, or someone affected by smoking, this is your complete guide to understanding the long-term respiratory complications of smoking—and how to protect yourself and others.Chapters00:00 – How Cigarette Smoke First Damages the Lungs00:28 – Lungs: The Organ Most Exposed to Smoking00:51 – The Respiratory Defense System and Cilia Destruction01:10 – Chronic Bronchitis: A Structural Disease01:33 – COPD Explained: Chronic Bronchitis + Emphysema01:52 – Emphysema: Alveolar Breakdown from Smoke02:24 – Symptoms and Clinical Progression of COPD02:47 – Asthma and the Smoking Connection03:04 – Asthma-COPD Overlap Syndrome (ACOS)03:14 – Smoking and Respiratory Infections03:32 – Idiopathic Pulmonary Fibrosis and Smoking03:44 – Cellular and Inflammatory Pathways of Damage04:15 – Genetic Susceptibility and Alpha-1 Antitrypsin Deficiency04:38 – A Typical COPD Patient Case05:02 – Diagnostic Tools: Spirometry, Imaging, and Blood Gases05:15 – Why Smoking Cessation Matters Most05:26 – Secondhand and Thirdhand Smoke Effects05:58 – Impact of Smoking During Pregnancy06:15 – Clinical Advice for Early Detection and Prevention06:59 – Patient Awareness: Link Smoking with Breathlessness07:09 – Teaser for the Next Episode: Smoking and Reproduction

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MDMA / Ecstasy

MDMA / Ecstasy

In episode 66 of Cracking Addiction we discuss MDMA or ecstacy and discuss its analogues PMA and PMMA and discuss the pharmacokinetics of these drugs, the unique properties of MDMA as both an atypical amphetamine-type substance and its effects as an empathogen. We also discuss the usage as both a recreational drug but also the new and emerging evidence of the clinical effects and benefits of MDMA and its increased usage in medical practice. MDMA has many effects on the body and we discuss the effects of MDMA on the brain, heart and liver in particular as well as some of the side effects of MDMA.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

16 Marras 202226min

GHB Withdrawal

GHB Withdrawal

In this episode of Cracking Addiction we discuss the timeframe of GHB withdrawal, the severe and significant symptoms of GHB withdrawal and the potential life threatening sequelae of GHB withdrawal. We explore the approach to GHB withdrawal management including medications that can assist to manage these symptoms and the need to speak specialist help promptly given the potential for significant deterioration.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

9 Marras 202219min

GHB

GHB

In this episode of Cracking Addiction we discuss GHB and its analogs GBL and 1,4-butanediol and the differences between these drugs. We explore the clinical indications for GHB as well as the pharmacology and pharmacokinetics of this drug. We discuss the side effects of GHB and some of the symptoms of GHB withdrawal.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

2 Marras 202215min

Higher and Friendly Powers

Higher and Friendly Powers

In this episode of Cracking Addiction we speak to Professor Peg O'Connor, a professor of moral philosophy who is in recovery from alcohol use disorder and who addresses an audience much like herself: those in recovery who have struggled with the Christian-centric God at the heart of Alcoholics Anonymous. She brings our attention to a little-known fact: the term “higher power,” a touchstone in the twelve steps of Alcoholics Anonymous, was coined by William James, philosopher, psychologist, and intellectual giant of the early 20th century. In this book Professor O'Connor addresses concepts such as:Understanding the Concept of “Higher Power” at the Heart of the 12-Step Program Why There Must Be Multiple Paths out of Addiction and No One is the Best or RightWhy Needs in Recovery Change over TimeUndertaking Spiritual Recovery in AA without a Religious DenominationProfessor O'Connor's book 'Higher and Friendly Powers: Transforming Addiction and Suffering' can be ordered from her website: https://pegoconnorauthor.com/ as well as Amazon, Barnes and Noble and Wildhouse Publications.

26 Loka 202235min

Using drugs in hospital

Using drugs in hospital

In this episode of Cracking Addiction we discuss people who use drugs whilst in hospital and discuss the ethics of treating people who use drugs, harm reduction measures that can assist with patient engagement, the stigma and marginalisation people who use drugs experience and the evidence and ethics around behaviour contracts.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

19 Loka 202221min

What is Kamini?and is it safe?

What is Kamini?and is it safe?

Kamini an Ayurvedic opiate-Kamini or Kamini Vidrawan Ras is an Ayurvedic medicine containing opiates as well as some heavy metals. It is a medicine marketed for a variety of indications ranging from premature ejaculation and impotence to increased stamina. There is increased recognition and awareness of patients presenting to specialist Addiction Medicine services with opioid dependence secondary to Kamini Vidrawan Ras often requiring treatment with opioid substitution therapy.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

12 Loka 202216min

Benzodiazepine withdrawal

Benzodiazepine withdrawal

In this episode of Cracking Addiction we discuss the timeframe and symptoms of benzodiazepine withdrawal, how to stabilise a patient on benzodiazepines and weaning and tapering of benzodiazepines within a community setting. We also discuss and highlight the importance of psychosocial support and lifestyle interventions in managing benzodiazepine dependence and withdrawal.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

5 Loka 202218min

Benzodiazepine use disorder

Benzodiazepine use disorder

In this episode of Cracking Addiction we discuss the effects of chronic benzodiazepine usage and the mechanisms of which tolerance and dependence to benzodiazepines develops and discuss the time course in which these syndromes can occur as well as discuss the diagnostic criteria for a benzodiazepine use disorder.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

28 Syys 202220min

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