#443: Kevin Klatt, PhD, RD - Can Choline Help Improve DHA Status?

#443: Kevin Klatt, PhD, RD - Can Choline Help Improve DHA Status?

A recently published study by Klatt and colleagues examined the impact of choline supplementation alongside DHA supplementation, versus DHA supplementation alone, on DHA status in pregnancy.

It is known that DHA is a critical nutrient at this time for healthy development of the child. And through a number of mechanisms discussed later, it has been hypothesized that choline could lead to greater DHA status.

We discuss:
  • What is the connection between choline and DHA? What is the PEMT pathway?
  • Study design for the choline + DHA trial
  • Are there risks of high-dose choline?
  • Main findings of the trial
  • How DHA status is not just a function of DHA intake, but also methyl metabolism too
  • Issues with omega-3 trials; e.g. not taking baseline status into account
  • Pragmatic recommendations for health professionals and patients
  • Different forms of choline supplements
  • Choline supplementation vs. food-derived choline
Access the show notes here Subscribe to Premium here

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Jaksot(642)

#619: How Much Fish Should a Healthy Diet Contain?

#619: How Much Fish Should a Healthy Diet Contain?

Most dietary guidelines recommend eating one to two servings of fish per week, often specifying that at least one serving should be oily fish. But how directly is that recommendation supported by evid...

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#618: How Wellness & Optimisation Culture Can Commodify Science – Nick Tiller, PhD

#618: How Wellness & Optimisation Culture Can Commodify Science – Nick Tiller, PhD

Wellness and optimisation culture increasingly presents itself as "science-based". But citing studies, using technical language, or having scientific credentials does not guarantee that the underlying...

1 Syys 56min

#617: What Does Effective Athlete Support Look Like in Practice? – Gemma McGuinness

#617: What Does Effective Athlete Support Look Like in Practice? – Gemma McGuinness

Effective athlete support requires more than delivering technically correct nutrition advice. It depends on understanding the athlete's wider environment, anticipating the pressures that disrupt good ...

25 Elo 46min

Fiber: Independent Benefits or Just a Proxy for Healthy Foods?

Fiber: Independent Benefits or Just a Proxy for Healthy Foods?

This episode answers one of the questions raised in the most recent Q&A episode on Sigma Nutrition Premium.  The full episode includes the following questions: Fiber: Independent effect or proxy for ...

18 Elo 21min

#616: More Testing, Better Health? Harms of Overdiagnosis & Overtreatment - Austin Baraki, MD

#616: More Testing, Better Health? Harms of Overdiagnosis & Overtreatment - Austin Baraki, MD

Medical screening is often framed as an uncomplicated good: if disease is found earlier, treatment can begin earlier and outcomes should improve. This episode examines why that reasoning is incomplete...

11 Elo 1h 15min

#615: Why Processing Doesn't Determine the Healthfulness of Plant-Based Diets – Alysha Thompson, PhD

#615: Why Processing Doesn't Determine the Healthfulness of Plant-Based Diets – Alysha Thompson, PhD

What does the evidence actually show when we look at plant-based dietary patterns through the lens of food processing? And does classifying foods as "ultra-processed" meaningfully change how we interp...

4 Elo 56min

#614: The Human Skills of Nutrition Coaching – Krista Scott-Dixon, PhD

#614: The Human Skills of Nutrition Coaching – Krista Scott-Dixon, PhD

In nutrition and health coaching, one of the central challenges is understanding how people actually change, particularly when life is complex, motivation fluctuates, and behaviour is shaped by emotio...

21 Heinä 56min

#613: Supplement Safety & Medication Interactions – Giulia Guerrini, MPharm

#613: Supplement Safety & Medication Interactions – Giulia Guerrini, MPharm

Supplement safety is often discussed in very general terms, but in practice the risks depend heavily on the individual. A supplement that is reasonable for one person may be inappropriate for another ...

14 Heinä 57min

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