Episode #214: A Deep Dive into Stem Cells and Exosomes (+ How to Stimulate Them without Therapy) with Dr. Amy Killen

Episode #214: A Deep Dive into Stem Cells and Exosomes (+ How to Stimulate Them without Therapy) with Dr. Amy Killen

In this episode of Biohacking Superhuman Performance with guest Dr. Amy Killen, we explore the world of stem cells - what they are, how they perform in the body, and how they work to increase longevity. Stem cell therapy is still being researched and regulated, but there is an amazing amount of potential for healing and increasing longevity with these powerful cells.

We also dive into exosomes - the small molecules that can penetrate places that stem cells can't. Aesthetic procedures are popular with exosomes- they have the power to restore hair and rejuvenate skin, and are used in many skincare products. We even go over ovarian rejuvenation and Rapamycin, a potential prescription drug for delaying menopause.

Overall, this episode offers guidance on stimulating stem cells right in your own home. We talk through different tips such as supplements, fasting, and getting sun in a healthy way for those who aren't in a place to budget for stem cell therapy.

Dr. Amy Killen is an outspoken advocate for empowering people to look and feel their best by merging lifestyle modification, integrative medicine, body-identical hormones, energy modalities, and stem cell therapies. She is the founder and CEO of the Human Optimization Project (HOP), a longevity-based subscription supplement company that stays on top of the science and constantly updates its ingredients for customers who can't devote their lives to reading the latest research sourcing the best therapies. I absolutely love her Instagram. You guys need to go follow her @dr.amybkillen.

Get Rapid Rebound oral BPC157 with PEA and AOD9604. Visit https://lelabs.co/ and use code NAT20



Thank you to our sponsors for making this episode possible:

Sensate: Use code NAT at www.getsensate.com/Nat

BEAM Minerals: Go to https://www.beamminerals.com code Nathalie to get 20% off your order

Profound Health: Use code longevity15 to save 15% off your first order at https://profound-health.com/



Find more from Dr. Amy B. Killen:

Website: https://dramykillen.com/

Youtube: https://www.youtube.com/channel/UCBLk8xTa4qzE7J8bID7KIKg

Instagram: @dr.amybkillen

Human Optimization Project (HOP box): https://hopbox.life/

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Instagram: https://www.instagram.com/nathalieniddam/

Website: https://www.NatNiddam.com

Join Nat's Membership Community: https://www.natniddam.com/bsp-community

Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

What We Discuss:

(1:30) Women's unfounded fear around Hormone Replacement Therapy

(5:38) When you start hormones early you reduce the risk of major women-killing diseases such as heart disease and obesity.

(7:20) The world of stem cells and exosomes- what they are, and why they are important.

(11:20) MSC cells are very safe, don't cause cancer, and they're not embryonic cells (no fetus is harmed!)

(13:50) The Pros of using birth product stem cells (from the placenta and umbilical cord)

(18:08) The environment where the stem cells are placed matters.

(22:50) Helpful therapies to stack with stem cell therapy.

(30:50) What the research shows about stem cell therapy and diseases like MS.

(34:15) Exosomes - one of the signaling molecules of stem cells. i

(41:37) Fat transfers are a great natural filler, but adding stem cells creates better results.

(44:50) How to stimulate stem cells naturally if you don't have the budget for stem cell therapy.

(58:30) The overuse of supplements and HOP box.

(1:04:00) Rapamycin and ovarian rejuvenation using stem cells.

(1:10:38) Where to find more from Dr. Amy B Killen.

Key Takeaways:

  • 1. Stem cells do two main things. They can replicate themselves and they can turn into other types of cells. Stem cells send out signals so that an injured area heals itself. When we age, we have fewer, less active stem cells. They aren't able to signal repair as well, so recovery takes much longer. Stem cell therapy gives you back signaling molecules so that you're able to heal yourself faster.
    Autologous stem cells are your own cells from fat tissue or bone marrow.
    Allogeneic stem cells come from somewhere else - like birth tissue products (placenta/umbilical cord).
  • The environment affects the stem cells. The area where you put stem cells matters, and if your body is not healthy, is inflamed, or has uncontrolled blood sugar issues, the cells cannot work as well. For example: a smoker or poorly controlled diabetic won't have the best results. Take the time to get in the best shape that you can before a costly procedure like stem cell therapy.
  • Exosomes are powerful signaling molecules that can be transported into cells to change the behavior of that cell. These small molecules can pass through the skin- they can be applied topically - and they can cross the blood brain barrier to decrease inflammation. They're great for aesthetic purposes like hair restoration and skin rejuvenation. The FDA regulates the application - they can only be applied topically.
  • Bonus takeaway: No drug can do what hormones do when used properly at the right time in the right way. If you want to be healthy for longer, especially after menopause, you need to be looking into HRT.

Jaksot(383)

#321: Stronger, Faster, Pain-Free? The Surprising Benefits of Whole Body Vibration with Dr. Jason Conviser

#321: Stronger, Faster, Pain-Free? The Surprising Benefits of Whole Body Vibration with Dr. Jason Conviser

Today, we're shaking things up—literally. My guest, Dr. Jason Conviser, is an exercise physiologist who specializes in helping people move better, whether they're elite athletes or 90-year-olds who just want to pick up their grandkids. And he's here to share the magnificent benefits of Power Plate. If you are already curious to learn more you can head to PowerPlate.com/nat to explore the benefits of Whole Body Vibration Therapy, and enjoy a special offer from Power Plate They're giving you 20% OFF and access to exclusive resources. What We discuss: Whole body vibration overview and personal introduction by Dr. Jason Conviser ... 00:06:29 Dr. Conviser's background and focus on medical fitness ... 00:07:25 Whole body vibration explained ... 00:12:09 Benefits of vibration for muscles and tendons ... 00:13:53 Warm-up efficiency and muscle performance ... 00:14:39 Recovery benefits of whole body vibration ... 00:15:21 Applications of whole body vibration across different fields ... 00:17:22 Insights on bone health and whole body vibration ... 00:23:17 Cortisol reduction benefits ... 00:23:51 Whole body vibration's role in achieving bone strength ... 00:24:21 Qualitative benefits of vibration in various populations ... 00:30:48 Case studies: Parkinson's and other conditions ... 00:32:33 Parkinson's and vibration therapy's impact ... 00:35:34 Frequency of use and practical applications ... 00:41:47 Power Plate's offerings and benefits of tools ... 01:02:09 Recommendations for young to middle-aged users ... 01:02:09 Complementary exercises with vibration and other tools ... 01:02:11 Vibration integration in cycling with Power Plate bike ... 01:02:11 Our Amazing Sponsors: LVLUP - Neuro Re-Generate is the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 15% off your order. Qualia Senolytic is a clinically tested formula with 9 plant-based, vegan ingredients designed to help your body clear out zombie cells—so you can feel younger, faster. Visit qualialife.com/nathalie and use promo code NATHALIE to save 15%! BiOptimizers - Magnesium Breakthrough - The only full-spectrum magnesium supplement with 7 unique forms of magnesium that your body can actually use and absorb. Visit bioptimizers.com/bionat and use code BIONAT for 10% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Grou

28 Maalis 1h 11min

#320: Master Muscle Mass At Any Age: How Bioavailable Peptides Are Revolutionizing Muscle Repair, Improving Gut Health, & Supporting Immune Function With Michael Antonelli

#320: Master Muscle Mass At Any Age: How Bioavailable Peptides Are Revolutionizing Muscle Repair, Improving Gut Health, & Supporting Immune Function With Michael Antonelli

In this episode of the Longevity Podcast, I'm thrilled to be joined by industry innovator Michael Antonelli, Founder & CEO of Healthgevity. Together, we dive deep into cutting-edge strategies for optimizing metabolism, muscle health, and immunity. Try Healthgevity and use promo code: NAT10. What We discuss: Michael Antonelli's background and journey ... 00:07:41 The inspiration behind Healthgevity ... 00:10:24 Introduction to metabolic health ... 00:19:16 Discussion on Ignite 2.0 formulation ... 00:20:16 Dosing flexibility of Ignite 2.0 ... 00:23:48 DNF10 and its role in Ignite 2.0 ... 00:30:10 Building muscle with longevity supplements ... 00:31:09 Introduction to PeptiStrong and its benefits ... 00:32:33 The importance of gut health and immunity ... 00:41:43 Prime Gut Health formula details ... 00:42:15 Discussion on Biorepair ... 00:55:56 Introduction to Immuno Reboot ... 01:00:37 Importance of sleep and Serenity product ... 01:02:26 Details on Serenity formulation ... 01:05:00 Conclusion and where to find Healthgevity products ... 01:11:37 Our Amazing Sponsors: Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face. Quantum Upgrade - Imagine plugging yourself into a limitless power source. It's been rigorously tested and shown to improve blood flow, reduce stress, and boost cellular energy by up to 29%. Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use code NAT10 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025. Wizard Sciences (Neural Rx) - Neural Rx isn't just about a quick boost. It's designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

25 Maalis 1h 14min

#319: Why You Need HONEY: Exploring the Medicinal Powers of Honey for Health and Longevity

#319: Why You Need HONEY: Exploring the Medicinal Powers of Honey for Health and Longevity

As a holistic nutritionist and epigenetic coach, I'm always looking for ways to blend modern biohacking techniques with timeless ancestral wisdom to help you take charge of your health and longevity. In this episode, we're diving deep into the wonders of honey—not just as a sweetener, but as a powerful healing agent that's been revered for centuries.    Products mentioned in the episode: Manukora - Visit http://manukora.com/NAT and use code NAT Beekeepers Naturals - Propolis Throat Spray Wyse Earth - Visit https://wyseearth.com/ and use code Longevity10 for 10% off Living Libations   What I discuss: The Unique Qualities of Honey ... 00:02:33 Honey's Medicinal Uses Through History ... 00:04:25 Living Libations' Honey Products ... 00:06:00 Wound Healing with Honey ... 00:07:15 Honey's Antimicrobial Properties ... 00:08:45 Honey in Endurance Activities ... 00:10:20 Trehalose and Its Benefits ... 00:12:05 Honey's Antioxidant Properties ... 00:14:00 MGO and Antibacterial Effects in Honey ... 00:15:45 Anti-inflammatory and Immune Support from Honey ... 00:17:50 Prebiotic Effects of Honey ... 00:19:20 Manuka Honey's Cancer Research ... 00:20:40   Our Amazing Sponsor: Just Thrive - 99% of probiotics on the market die in your stomach before they even reach your gut. Just Thrive is the only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90 day bottle.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

21 Maalis 30min

#318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin

#318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin

In today's episode, I'm thrilled to share a captivating conversation with Dr. Robert Lufkin, a distinguished physician and medical school professor. Dr. Lufkin, the author of the groundbreaking book "Lies I Taught in Medical School," offers unique insights from his perspective within the medical establishment. We dive deep into the shortcomings of modern medicine, especially when it comes to addressing chronic diseases like obesity, diabetes, and cardiovascular issues. What We discuss: Dr. Lufkin's Background and Perspective ... 00:07:21 Modern Medicine and Chronic Disease Challenges ... 00:11:48 Dr. Lufkin's Personal Health Journey ... 00:13:37 Importance of Lifestyle in Medical Treatment ... 00:17:39 Type 2 Diabetes and Aging ... 00:28:11 Perspective on Cardiovascular Health ... 01:01:16 Discussion on Statins ... 01:04:16 General Practitioner Role and Medical System ... 00:21:33 Diet and Nutritional Insights ... 00:43:23 Fasting and Metabolic Health ... 00:51:15 Stress Management and Childhood Events Impact ... 00:38:45 Dr. Lufkin's Views on Supplements ... 01:09:35 Where to Find Dr. Robert Lufkin's Book ... 01:12:25 Our Amazing Sponsors: Profound Health - Nature's Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They're manufactured in the UK. They're GMP and HACCP certified and FDA-compliant. Whatever your health needs, there's a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order. Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order! Timeline - Improve your cellular energy, strengthen muscle, and boost endurance by taking Mitopure daily. Mitopure unlocks 6x more Urolithin A than diet alone. Visit timeline.com/nat10 for 10% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

18 Maalis 1h 14min

#317 How Nitric Oxide Supports Digestion, Circulation, and Sexual Function in Men & Women With Cathy Eason

#317 How Nitric Oxide Supports Digestion, Circulation, and Sexual Function in Men & Women With Cathy Eason

Today, Cathy Eason, MS, BCHN and Clinical Education Director at Berkeley Life, fills us in on the MANY functional benefits of nitric oxide. We're diving deep into the fascinating world of nitric oxide—a tiny yet mighty molecule that's essential for a myriad of bodily functions such as blood flow, energy production, and hormone regulation. Offer for NEW and EXISTING Customers: New customers - visit berkeleylifeprofessional.com/NAT and enter code SAVE20 to save $20 off your first order. Existing customers of Berkeley Life Pro - email info@berkeleylife.com and tell them Nathalie sent you and you will get a free pack of the Prebiotic Nitrate Chewing Gum we talk about in the episode. What We discuss: Importance and functions of nitric oxide ... 00:00:45 Decline of nitric oxide production with age and dietary sources ... 00:08:23 Challenges with nitric oxide production: genetics, age, and lifestyle ... 00:17:55 Impacts of lifestyle choices on nitric oxide levels ... 00:22:10 Role of nitric oxide in digestion, sexual health, and immune regulation ... 00:29:09 Relevance of mitochondria and energy production with nitric oxide ... 00:38:12 Link between nitric oxide and metabolic balance ... 00:49:05 Supplementation options and Berkeley Life's approach ... 00:54:06 Using the Berkeley Life gum to support oral biome ... 01:08:55 Details on special offers for listeners ... 01:13:08 Our Amazing Sponsors: Wizard Sciences (Neural Rx) - Neural Rx isn't just about a quick boost. It's designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com. BEAM Minerals - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that's now one of the most mineral-dense substances on earth. That's what's going into your body—and your cells absorb it within minutes. Visit beamminerals.com/NAT20 and use code NAT20 for 20% off. Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

14 Maalis 1h 15min

#316: The Science of Joy: How Darkness and Sound Therapy Can Shift Your Entire Being Towards Happiness and Contentment With Pavel Stuchlik

#316: The Science of Joy: How Darkness and Sound Therapy Can Shift Your Entire Being Towards Happiness and Contentment With Pavel Stuchlik

Today we get to immerse ourselves into the realm of joy and self-discovery with our special guest, Pavel Stuchlik. Pavel, an ex-professional cyclist and a dynamic human optimization expert, joins us to share insights into living a life full of happiness and coherence. Offer from Pavel: Here is lifetime FREE community with 7 day commitment to you. There are videos, courses, and a wonderful community that awaits you. - https://www.skool.com/systemreset What We discuss: Pavel's Story and Journey ... 00:07:01 Darkroom Experience and Revelation ... 00:11:55 The Concept of NOA AON ... 00:14:44 Solfeggio Frequencies and Their Impact ... 00:15:14 Quantifying Emotional and Mental Shifts ... 00:18:42 Unhooking Process and Its Importance ... 00:21:06 Importance of Dreaming and Visualization ... 01:03:31 Physical Health and Biohacking Benefits ... 01:04:12 Our Amazing Sponsors: Quantum Upgrade - Imagine plugging yourself into a limitless power source. It's been rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%. Visit quantumupgrade.io/NAT and start running life, instead of life running you.Use my code NAT10 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025 Manukora.com/NAT - Supports immunity and gut health with high levels of antioxidants and prebiotics and MGO powerful antimicrobial compounds. 70% of the antioxidants found in Manukora honey are not found in any other honey! Head to Manukora.com/NAT to get $25 off the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook! LVLUP: The secret to CREvolution? It's all about GAA. This powerful compound helps you get more creatine into your cells faster than traditional creatine. Ready to crush your next workout? Head to lvluphealth.com and use the code NAT for 15% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

11 Maalis 1h 11min

#315: Molecular Hydrogen: Tiny Molecule, Massive Health Impacts and So EASY to Add to Your Routine With Nathalie Niddam

#315: Molecular Hydrogen: Tiny Molecule, Massive Health Impacts and So EASY to Add to Your Routine With Nathalie Niddam

Join me as I explore this tiny yet incredibly powerful molecule that offers a plethora of health benefits. From its ability to manage inflammation and oxidative stress to enhancing exercise performance and recovery, molecular hydrogen is a fascinating subject in the realm of biohacking and longevity. Hydrogen Products Mentioned: Hyest - https://www.hyestvitamins.com/?ref=LONGEVITY - Use Code: LONGEVITY for 10% off DrinkHRW - visit https://drinkhrw.com/superhuman use code LONGEVITY for 15% off What We discuss: Hydrogen's Unique Properties ... 00:01:00 Hydrogen Supplementation Methods ... 00:04:30 Preferred Hydrogen Tablets ... 00:07:00 Research and Human Studies on Hydrogen ... 00:10:00 Selective Antioxidant and Anti-inflammatory Benefits ... 00:13:00 Exercise and Recovery Benefits ... 00:16:00 Cardiovascular Health Benefits ... 00:17:30 Neuroprotective Effects ... 00:20:00 Our Amazing Sponsor: BiOptimizers - Magnesium Breakthrough - BiOptimizers: It's the only full-spectrum magnesium supplement with 7 unique forms of magnesium that your body can actually use and absorb. Go to bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

7 Maalis 31min

#314: The DARK Truth About Seed Oils, Cholesterol & Nutrition Myths—Revealed by Dr. Cate Shanahan

#314: The DARK Truth About Seed Oils, Cholesterol & Nutrition Myths—Revealed by Dr. Cate Shanahan

Welcome back, Longevity listeners! I'm excited to dive into today's episode, in which we explore the controversial world of seed oils with the insightful Dr. Cate Shanahan, a Cornell-trained physician-scientist and author of Dark Calories. As a nutritionist and epigenetic coach, I'm thrilled to unpack the complex relationship between vegetable oils, cholesterol, and heart health with you all. What We discuss: Dr. Cate Shanahan's journey into nutrition ... 06:38 Cate's perspective on medical training ... 10:56 Framework of the four pillars of traditional diets ... 17:16 Importance and challenges of modern food industry ... 25:06 Understanding processed foods and oxidation ... 27:24 Harmful effects of vegetable oils ... 33:00 Busting myths about cholesterol ... 42:10 Misconceptions about saturated fats and genetics ... 52:11 Dr. Cate's views on cooking oils ... 59:07 Balancing taste and health in cooking ... 01:06:36 Our Amazing Sponsors: Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order! Timeline - Improve your cellular energy, strengthen muscle, and boost endurance by taking Mitopure daily. Mitopure unlocks 6x more Urolithin A than diet alone. Visit timeline.com/nat10 for 10% off. Just Thrive - 99% of probiotics on the market die in your stomach before they even reach your gut. Just Thrive is the only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90-day bottle. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

4 Maalis 1h 20min

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