Episode #223: The Microbiome and Its Effects on All Other Bodily Systems with Chidozie Ojobor, Ph.D.

Episode #223: The Microbiome and Its Effects on All Other Bodily Systems with Chidozie Ojobor, Ph.D.

Optimizing your gut microbiome is arguably one of the most important things you can do for your health as it plays so many integral roles in almost every body system. This is why, in this episode of Biohacking Superhuman Performance, I chat with Chidozie Ojobor, Ph.D. about the importance of the microbiome's influence on human health, particularly on the gut-brain connection and mental well-being.

He discusses the role of butyrate, leaky gut/brain, probiotics, and the importance of diet diversity in promoting a healthy microbiome. The conversation also covers the impact of modern lifestyle, antibiotics, and colon cleansing on gut health, and how to get accessible gut microbiome testing - in particular, the testing done by Vitract.

Chidozie Ojobor Ph.D. is a Molecular Biologist with over 12 years of experience in Medical Microbiology research, and the co-founder and Chief Science Officer of Vitract. In his early research years, he worked on human rotaviruses that cause severe gastroenteritis in children.

Afterward, he proceeded to earn his Ph.D. in Molecular Genetics from the University of Toronto, Canada. During his doctoral training, he developed through genetic engineering, novel therapeutic entities that target disease-causing bacteria such as the ones found in complex biological ecosystems as the gut microbiome. These tools he developed worked with high specificity and precision, making them the ideal candidates for targeted therapy. Dr. Ojobor's works in the fields he worked in have been well-cited by numerous scientists across the globe.



Thank you to our sponsors for making this episode possible:

CAROL Bike: Use code NAT for $100 off at www.carolbike.com

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BiOptimizers: For Sleep Breakthrough use code bionat at checkout to save on your order and receive free gifts at www.bioptimizers.com/bionat

Find more from Chidozie Ojobor:

Website: https://vitract.com/

Instagram: @vitractofficial

Use Code NAT10 at vitract.com to save on a Vitract test

Find more from Nathalie:

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Website: NatNiddam.com

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

What We Discuss:

00:00 Introduction and Background

00:52 Advancements in Microbiome Research

04:39 The Significance of the Microbiome

05:09 The Gut-Brain Connection

06:22 Microbiome and Mental Health

08:11 The Role of Butyrate in Gut Health

09:06 Butyrate Supplementation

14:05 Leaky Gut and Leaky Brain

21:11 Foods that Promote Butyrate Production

23:06 Probiotics and Microbiome Diversity

29:23 The Role of Geography and Lifestyle in Gut Microbiome

30:03 The Importance of Gut Diversity for Health

31:35 Impact of Modern Lifestyle on Gut Diversity

32:30 Adaptation of the Gut Microbiome to the Environment

34:03 The Influence of Environmental Factors on the Gut Microbiome

35:14 The Complexity of Achieving the 'Perfect' Gut Microbiome

36:03 The Functional Level of the Gut Microbiome

37:19 The Impact of Antibiotics on the Gut Microbiome

39:10 The Resilience of the Gut Microbiome

40:33 The Use of Probiotics During Antibiotic Treatment

45:36 The Detrimental Effects of Prolonged Antibiotic Usage

48:19 The Link Between Food Poisoning and Gut Health

49:17 The Detrimental Effects of Colon Cleansing

50:45 The Controversy Surrounding Enemas and Colonics

53:19 The Impact of Chronic Stress and Antibiotic Overuse on the Microbiome

54:04 The Transition to Gut Microbiome Testing

55:28 The Need for Affordable and Comprehensive Gut Microbiome Tests

56:21 Understanding the Vytract Gut Microbiome Test

58:09 Transparency and Personalization in Gut Microbiome Testing

59:42 Short-Term Variability and Clinical Utility of Microbiome Testing

01:03:41 The Importance of Accepting Differences in Dietary Approaches

01:09:47 The Focus of Vytract's Gut Microbiome Test

01:11:30 Where to Find More Information and Order a Vitract Test



Key Takeaways:

  • Reduced gut diversity, often seen in individuals living in civilized nations, can have negative health implications.

  • Antibiotics can disrupt the gut microbiome, and the use of probiotics during and after antibiotic treatment may help restore balance.

  • Prolonged antibiotic usage can have long-term consequences for gut health, including increased risk of certain conditions.

  • Colon cleansing and enemas may have detrimental effects on the gut microbiome and should be approached with caution. Chronic stress and antibiotic overuse can disrupt the microbiome.

  • Gut microbiome testing provides valuable insights into gut health.

  • Affordable and comprehensive tests are needed to improve access to microbiome testing.

  • Short-term changes in the microbiome can have clinical utility.

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#321: Stronger, Faster, Pain-Free? The Surprising Benefits of Whole Body Vibration with Dr. Jason Conviser

#321: Stronger, Faster, Pain-Free? The Surprising Benefits of Whole Body Vibration with Dr. Jason Conviser

Today, we're shaking things up—literally. My guest, Dr. Jason Conviser, is an exercise physiologist who specializes in helping people move better, whether they're elite athletes or 90-year-olds who just want to pick up their grandkids. And he's here to share the magnificent benefits of Power Plate. If you are already curious to learn more you can head to PowerPlate.com/nat to explore the benefits of Whole Body Vibration Therapy, and enjoy a special offer from Power Plate They're giving you 20% OFF and access to exclusive resources. What We discuss: Whole body vibration overview and personal introduction by Dr. Jason Conviser ... 00:06:29 Dr. Conviser's background and focus on medical fitness ... 00:07:25 Whole body vibration explained ... 00:12:09 Benefits of vibration for muscles and tendons ... 00:13:53 Warm-up efficiency and muscle performance ... 00:14:39 Recovery benefits of whole body vibration ... 00:15:21 Applications of whole body vibration across different fields ... 00:17:22 Insights on bone health and whole body vibration ... 00:23:17 Cortisol reduction benefits ... 00:23:51 Whole body vibration's role in achieving bone strength ... 00:24:21 Qualitative benefits of vibration in various populations ... 00:30:48 Case studies: Parkinson's and other conditions ... 00:32:33 Parkinson's and vibration therapy's impact ... 00:35:34 Frequency of use and practical applications ... 00:41:47 Power Plate's offerings and benefits of tools ... 01:02:09 Recommendations for young to middle-aged users ... 01:02:09 Complementary exercises with vibration and other tools ... 01:02:11 Vibration integration in cycling with Power Plate bike ... 01:02:11 Our Amazing Sponsors: LVLUP - Neuro Re-Generate is the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 15% off your order. Qualia Senolytic is a clinically tested formula with 9 plant-based, vegan ingredients designed to help your body clear out zombie cells—so you can feel younger, faster. Visit qualialife.com/nathalie and use promo code NATHALIE to save 15%! BiOptimizers - Magnesium Breakthrough - The only full-spectrum magnesium supplement with 7 unique forms of magnesium that your body can actually use and absorb. Visit bioptimizers.com/bionat and use code BIONAT for 10% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Grou

28 Maalis 1h 11min

#320: Master Muscle Mass At Any Age: How Bioavailable Peptides Are Revolutionizing Muscle Repair, Improving Gut Health, & Supporting Immune Function With Michael Antonelli

#320: Master Muscle Mass At Any Age: How Bioavailable Peptides Are Revolutionizing Muscle Repair, Improving Gut Health, & Supporting Immune Function With Michael Antonelli

In this episode of the Longevity Podcast, I'm thrilled to be joined by industry innovator Michael Antonelli, Founder & CEO of Healthgevity. Together, we dive deep into cutting-edge strategies for optimizing metabolism, muscle health, and immunity. Try Healthgevity and use promo code: NAT10. What We discuss: Michael Antonelli's background and journey ... 00:07:41 The inspiration behind Healthgevity ... 00:10:24 Introduction to metabolic health ... 00:19:16 Discussion on Ignite 2.0 formulation ... 00:20:16 Dosing flexibility of Ignite 2.0 ... 00:23:48 DNF10 and its role in Ignite 2.0 ... 00:30:10 Building muscle with longevity supplements ... 00:31:09 Introduction to PeptiStrong and its benefits ... 00:32:33 The importance of gut health and immunity ... 00:41:43 Prime Gut Health formula details ... 00:42:15 Discussion on Biorepair ... 00:55:56 Introduction to Immuno Reboot ... 01:00:37 Importance of sleep and Serenity product ... 01:02:26 Details on Serenity formulation ... 01:05:00 Conclusion and where to find Healthgevity products ... 01:11:37 Our Amazing Sponsors: Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face. Quantum Upgrade - Imagine plugging yourself into a limitless power source. It's been rigorously tested and shown to improve blood flow, reduce stress, and boost cellular energy by up to 29%. Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use code NAT10 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025. Wizard Sciences (Neural Rx) - Neural Rx isn't just about a quick boost. It's designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

25 Maalis 1h 14min

#319: Why You Need HONEY: Exploring the Medicinal Powers of Honey for Health and Longevity

#319: Why You Need HONEY: Exploring the Medicinal Powers of Honey for Health and Longevity

As a holistic nutritionist and epigenetic coach, I'm always looking for ways to blend modern biohacking techniques with timeless ancestral wisdom to help you take charge of your health and longevity. In this episode, we're diving deep into the wonders of honey—not just as a sweetener, but as a powerful healing agent that's been revered for centuries.    Products mentioned in the episode: Manukora - Visit http://manukora.com/NAT and use code NAT Beekeepers Naturals - Propolis Throat Spray Wyse Earth - Visit https://wyseearth.com/ and use code Longevity10 for 10% off Living Libations   What I discuss: The Unique Qualities of Honey ... 00:02:33 Honey's Medicinal Uses Through History ... 00:04:25 Living Libations' Honey Products ... 00:06:00 Wound Healing with Honey ... 00:07:15 Honey's Antimicrobial Properties ... 00:08:45 Honey in Endurance Activities ... 00:10:20 Trehalose and Its Benefits ... 00:12:05 Honey's Antioxidant Properties ... 00:14:00 MGO and Antibacterial Effects in Honey ... 00:15:45 Anti-inflammatory and Immune Support from Honey ... 00:17:50 Prebiotic Effects of Honey ... 00:19:20 Manuka Honey's Cancer Research ... 00:20:40   Our Amazing Sponsor: Just Thrive - 99% of probiotics on the market die in your stomach before they even reach your gut. Just Thrive is the only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90 day bottle.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

21 Maalis 30min

#318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin

#318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin

In today's episode, I'm thrilled to share a captivating conversation with Dr. Robert Lufkin, a distinguished physician and medical school professor. Dr. Lufkin, the author of the groundbreaking book "Lies I Taught in Medical School," offers unique insights from his perspective within the medical establishment. We dive deep into the shortcomings of modern medicine, especially when it comes to addressing chronic diseases like obesity, diabetes, and cardiovascular issues. What We discuss: Dr. Lufkin's Background and Perspective ... 00:07:21 Modern Medicine and Chronic Disease Challenges ... 00:11:48 Dr. Lufkin's Personal Health Journey ... 00:13:37 Importance of Lifestyle in Medical Treatment ... 00:17:39 Type 2 Diabetes and Aging ... 00:28:11 Perspective on Cardiovascular Health ... 01:01:16 Discussion on Statins ... 01:04:16 General Practitioner Role and Medical System ... 00:21:33 Diet and Nutritional Insights ... 00:43:23 Fasting and Metabolic Health ... 00:51:15 Stress Management and Childhood Events Impact ... 00:38:45 Dr. Lufkin's Views on Supplements ... 01:09:35 Where to Find Dr. Robert Lufkin's Book ... 01:12:25 Our Amazing Sponsors: Profound Health - Nature's Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They're manufactured in the UK. They're GMP and HACCP certified and FDA-compliant. Whatever your health needs, there's a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order. Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order! Timeline - Improve your cellular energy, strengthen muscle, and boost endurance by taking Mitopure daily. Mitopure unlocks 6x more Urolithin A than diet alone. Visit timeline.com/nat10 for 10% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

18 Maalis 1h 14min

#317 How Nitric Oxide Supports Digestion, Circulation, and Sexual Function in Men & Women With Cathy Eason

#317 How Nitric Oxide Supports Digestion, Circulation, and Sexual Function in Men & Women With Cathy Eason

Today, Cathy Eason, MS, BCHN and Clinical Education Director at Berkeley Life, fills us in on the MANY functional benefits of nitric oxide. We're diving deep into the fascinating world of nitric oxide—a tiny yet mighty molecule that's essential for a myriad of bodily functions such as blood flow, energy production, and hormone regulation. Offer for NEW and EXISTING Customers: New customers - visit berkeleylifeprofessional.com/NAT and enter code SAVE20 to save $20 off your first order. Existing customers of Berkeley Life Pro - email info@berkeleylife.com and tell them Nathalie sent you and you will get a free pack of the Prebiotic Nitrate Chewing Gum we talk about in the episode. What We discuss: Importance and functions of nitric oxide ... 00:00:45 Decline of nitric oxide production with age and dietary sources ... 00:08:23 Challenges with nitric oxide production: genetics, age, and lifestyle ... 00:17:55 Impacts of lifestyle choices on nitric oxide levels ... 00:22:10 Role of nitric oxide in digestion, sexual health, and immune regulation ... 00:29:09 Relevance of mitochondria and energy production with nitric oxide ... 00:38:12 Link between nitric oxide and metabolic balance ... 00:49:05 Supplementation options and Berkeley Life's approach ... 00:54:06 Using the Berkeley Life gum to support oral biome ... 01:08:55 Details on special offers for listeners ... 01:13:08 Our Amazing Sponsors: Wizard Sciences (Neural Rx) - Neural Rx isn't just about a quick boost. It's designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com. BEAM Minerals - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that's now one of the most mineral-dense substances on earth. That's what's going into your body—and your cells absorb it within minutes. Visit beamminerals.com/NAT20 and use code NAT20 for 20% off. Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

14 Maalis 1h 15min

#316: The Science of Joy: How Darkness and Sound Therapy Can Shift Your Entire Being Towards Happiness and Contentment With Pavel Stuchlik

#316: The Science of Joy: How Darkness and Sound Therapy Can Shift Your Entire Being Towards Happiness and Contentment With Pavel Stuchlik

Today we get to immerse ourselves into the realm of joy and self-discovery with our special guest, Pavel Stuchlik. Pavel, an ex-professional cyclist and a dynamic human optimization expert, joins us to share insights into living a life full of happiness and coherence. Offer from Pavel: Here is lifetime FREE community with 7 day commitment to you. There are videos, courses, and a wonderful community that awaits you. - https://www.skool.com/systemreset What We discuss: Pavel's Story and Journey ... 00:07:01 Darkroom Experience and Revelation ... 00:11:55 The Concept of NOA AON ... 00:14:44 Solfeggio Frequencies and Their Impact ... 00:15:14 Quantifying Emotional and Mental Shifts ... 00:18:42 Unhooking Process and Its Importance ... 00:21:06 Importance of Dreaming and Visualization ... 01:03:31 Physical Health and Biohacking Benefits ... 01:04:12 Our Amazing Sponsors: Quantum Upgrade - Imagine plugging yourself into a limitless power source. It's been rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%. Visit quantumupgrade.io/NAT and start running life, instead of life running you.Use my code NAT10 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025 Manukora.com/NAT - Supports immunity and gut health with high levels of antioxidants and prebiotics and MGO powerful antimicrobial compounds. 70% of the antioxidants found in Manukora honey are not found in any other honey! Head to Manukora.com/NAT to get $25 off the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook! LVLUP: The secret to CREvolution? It's all about GAA. This powerful compound helps you get more creatine into your cells faster than traditional creatine. Ready to crush your next workout? Head to lvluphealth.com and use the code NAT for 15% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

11 Maalis 1h 11min

#315: Molecular Hydrogen: Tiny Molecule, Massive Health Impacts and So EASY to Add to Your Routine With Nathalie Niddam

#315: Molecular Hydrogen: Tiny Molecule, Massive Health Impacts and So EASY to Add to Your Routine With Nathalie Niddam

Join me as I explore this tiny yet incredibly powerful molecule that offers a plethora of health benefits. From its ability to manage inflammation and oxidative stress to enhancing exercise performance and recovery, molecular hydrogen is a fascinating subject in the realm of biohacking and longevity. Hydrogen Products Mentioned: Hyest - https://www.hyestvitamins.com/?ref=LONGEVITY - Use Code: LONGEVITY for 10% off DrinkHRW - visit https://drinkhrw.com/superhuman use code LONGEVITY for 15% off What We discuss: Hydrogen's Unique Properties ... 00:01:00 Hydrogen Supplementation Methods ... 00:04:30 Preferred Hydrogen Tablets ... 00:07:00 Research and Human Studies on Hydrogen ... 00:10:00 Selective Antioxidant and Anti-inflammatory Benefits ... 00:13:00 Exercise and Recovery Benefits ... 00:16:00 Cardiovascular Health Benefits ... 00:17:30 Neuroprotective Effects ... 00:20:00 Our Amazing Sponsor: BiOptimizers - Magnesium Breakthrough - BiOptimizers: It's the only full-spectrum magnesium supplement with 7 unique forms of magnesium that your body can actually use and absorb. Go to bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

7 Maalis 31min

#314: The DARK Truth About Seed Oils, Cholesterol & Nutrition Myths—Revealed by Dr. Cate Shanahan

#314: The DARK Truth About Seed Oils, Cholesterol & Nutrition Myths—Revealed by Dr. Cate Shanahan

Welcome back, Longevity listeners! I'm excited to dive into today's episode, in which we explore the controversial world of seed oils with the insightful Dr. Cate Shanahan, a Cornell-trained physician-scientist and author of Dark Calories. As a nutritionist and epigenetic coach, I'm thrilled to unpack the complex relationship between vegetable oils, cholesterol, and heart health with you all. What We discuss: Dr. Cate Shanahan's journey into nutrition ... 06:38 Cate's perspective on medical training ... 10:56 Framework of the four pillars of traditional diets ... 17:16 Importance and challenges of modern food industry ... 25:06 Understanding processed foods and oxidation ... 27:24 Harmful effects of vegetable oils ... 33:00 Busting myths about cholesterol ... 42:10 Misconceptions about saturated fats and genetics ... 52:11 Dr. Cate's views on cooking oils ... 59:07 Balancing taste and health in cooking ... 01:06:36 Our Amazing Sponsors: Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order! Timeline - Improve your cellular energy, strengthen muscle, and boost endurance by taking Mitopure daily. Mitopure unlocks 6x more Urolithin A than diet alone. Visit timeline.com/nat10 for 10% off. Just Thrive - 99% of probiotics on the market die in your stomach before they even reach your gut. Just Thrive is the only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90-day bottle. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

4 Maalis 1h 20min

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