Biohacking News Weekly Update : 1363

Biohacking News Weekly Update : 1363

This episode covers:


• Cocoa Extract Cuts Heart Deaths

A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient.

Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm


• AI Stethoscope for Home Diagnostics

Lapsi Health’s Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit.

Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com


• Beef Organ Supplements Surge

Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition.

Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com


• Spirulina for Collagen and DNA Protection

New research highlights spirulina’s ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress.

Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx


• Health Data Privacy Reform

A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud.

Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025


All source links provided for easy reference to the original reporting and research above.


This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women’s hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates


Thank you to our sponsors!


Resources:

• Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome

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• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 – Intro

0:19 – Cocoa Extract & Heart Health

1:52 – AI Digital Stethoscope

3:01 – Beef Organ Supplements

4:24 – Spirulina for Longevity

5:42 – Substack Announcement

6:53 – Health Data Privacy Reform

8:23 – Weekly Upgrade Protocol

9:46 – Outro

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1425)

Control Your Mindset with 4 Questions – Legacy Upgrade ft. Byron Katie : 965

Control Your Mindset with 4 Questions – Legacy Upgrade ft. Byron Katie : 965

IN THIS EPISODE OF THE HUMAN UPGRADE™...…a legacy upgrade conversation with Byron Katie will have you digging deep into the work of fine-tuning your mindset. Her keystone practice, The Work, allows you to access the wisdom you already hold inside you. She explains it as a process to “clear the mind.”You’ll ask yourself four questions and apply them to a specific problem you’re facing. Going through these steps gives you perspective and a new way of thinking about what’s causing you distress. Questioning diminishes the power your thoughts have over you. And THAT leads to true freedom.Her work contains elements of therapist, a counselor or a religious leader, though she’s technically not any one of these. She’s been described as a spiritual mentor. As the bestselling author of “Loving What Is: Four Questions That Can Change Your Life," followed by "A Mind at Home with Itself: How Asking Four Questions Can Free Your Mind, Open Your Heart, and Turn Your World Around," her inspirational guidance offers people a different way to think their thoughts so they can change their mindsets and, ultimately, their lives.Her own story of early life success that spiraled into depression, rage, addiction, and self-loathing, sets the foundation for The Work. “The thoughts like, “I’m not good enough. There's something wrong with me," which was true,” Byron explains. “It was my thinking. My thoughts were aimed out at other people. It was their fault. Then when I would say or do something, I would experience the guilt, so I had this vicious circle going of judgment, guilt, judgment, guilt. It was debilitating.”She had to save herself. Several weeks into treatment, she woke up one morning to a state of constant joy that has never left her and four questions clearly in her mind that would lead her out of her own darkness. She’s never been able to truly explain this epiphany, nor has she evangelized it. She realized that when she believed her stressful thoughts, she suffered, but that when she questioned them, she didn't suffer, and that this is true for every human being. She simply shares The Work with people who want to make profound life changes—and has continued this path for nearly 40 years.“I have a lot of people across the globe that are saying their lives are shifting so dramatically they're unrecognizable, but I don't call it The Work for nothing,” she says. “It does take stillness. It takes silence, and it takes being courageous enough to look at the thoughts in your head without trying to change them and accept them the way they are.”WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Kickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Elo 202253min

Upgrade Spotlight: Cook Faster, Easier & Better With Light – Brava : 964

Upgrade Spotlight: Cook Faster, Easier & Better With Light – Brava : 964

IN THIS EPISODE OF THE HUMAN UPGRADE™...... you’re going to find out how to cook differently using an innovative kitchen appliance, Brava, that’s got some cool features that will get you excited about making your meals at home—always a good idea!First—what Brava is not. The Brava countertop cooking oven isn’t a microwave, isn’t a toaster oven, and isn’t a convection oven.Instead, it’s a device that cooks with light. Six lamps deliver exact, variable, infrared light waves to your food. Brava synchronizes and controls the amount of power each lamp emits. Simultaneously, the lamps instantly reach full power and turn off just as quickly, creating three independent cooking zones inside the chamber. The top five benefits of this cooking method include: Searing (great for your grass-fed steaks), precision, versatility, speed and quality. Brava also cooks up to three different ingredients at the same time. You can air fry, dehydrate and cook your favorite white rice in it (Bulletproof Diet approved). It’s user- and kid-friendly, so your whole family can be part of a lifestyle that prioritizes food that nourishes your body and ups your energy.Brava’s vice president and professional chef, Travis Rea, led the Brava Culinary Team in developing Brava's patented Pure Light Technology (physicists and mathematicians were in on it, too). He’s on the show to explain the technology behind Brava and how cooking with light will change your entire approach to food.Travis earned a degree in Culinary Arts at the California Culinary Academy. Prior to Brava, he headed the Food Development team at Williams-Sonoma for eight years where he developed nearly 800 private label food products. His experience also includes leadership roles at Revolution Foods and NatureBox. So, he knows the many facets of creating great food.Brava takes out the guesswork of meal planning by offering over 7,000 fully automated recipe programs. This means you can enjoy cooking more because it takes less of your time.SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: https://www.brava.com, use code DAVE at checkout to get $200 OFF any Brava set through December 31, 2022. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Elo 202235min

How Whole Body Vibration Hacks Fitness & Fat Loss – Tony Molina : 963

How Whole Body Vibration Hacks Fitness & Fat Loss – Tony Molina : 963

IN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll learn how whole body vibration works and the many ways it benefits your physiology. It’s the nexus between energy and life, says Tony Molina, a performance optimization expert.“This biohack helps you burn more calories,” he says. “It helps you increase strength and reaction time. You can improve skin and circulation, bone density, pain relief, hormonal changes, posture and balance. It's also a lifelong health and longevity partner.” He’s talking about the Power Plate. He’s a high-altitude and longevity researcher and Senior Research and Development Specialist at the company.“Whole body vibration runs off Isaac Newton's second law, so force equals mass times acceleration,” he explains. “Where acceleration is what’s being increased versus mass. And generally, we focus on the mass, whether we do any kind of strength training, we focus on holding mass or dealing with the mass or changing the mass. With whole body vibration and Power Plate, you’re focusing on the acceleration or the speed change.”Other cool things about whole body vibration:You're changing the formula from conscious effort (like conventional exercise) to subconscious (harmonic vibration).You’re experiencing multiplanar movement that creates an unstable environment that’s proprioceptively challenging. (The nervous system doesn't know what to do, which is a good thing.)Your neuromuscular spindle gets stimulated without the need for the brain even to get involved. (Cognitive confidence!) Your nervous system itself is ramping up safety signals so the brain understands what it needs to do without you consciously having to do anything.Your reflexes improve; your reaction time gets better; your ability to propriocept allows your posture to improve; and you breathe better.Listen on to find out more about whole-body vibration training, therapy, and how it can make you live longer, whatever your fitness level or ability.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://powerplate.com/dave to get 20% off a Power Plate® MOVE (save $659) AND a FREE Power Plate Pulse Massage Gun (valued at $249.99) WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Increase BDNF and Support Neurogenesis: Go to https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% offA Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesCooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Elo 202254min

How to Hack Your Metabolism and Power Your Energy – Michal Mor, Ph.D. : 962

How to Hack Your Metabolism and Power Your Energy – Michal Mor, Ph.D. : 962

IN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn about the critical role metabolism plays in your body’s energy and performance. Important new science findings about human metabolic health shows how you can change your metabolism. To help you make these changes, this episode gives you practical tips and tools for measuring your metabolism and ways to manage it effectively.Guest Michal Mor, Ph.D., co-founded Lumen with her twin sister, Merav Mor, Ph.D., and three long-time entrepreneur friends nearly a decade ago. As Chief of Metabolic Health & Science, Michal’s background includes degree studies in Medical Laboratory Sciences and Physiology with an emphasis on cardiac arrhythmia. The Lumen founders set out to close the gap of what existed in the science and something people could actually use to manage their metabolic health.Both Michal and her twin, Merav, were multiple-year Ironman participants. Athletic performance—and how to improve it—influenced their work with metabolism. Four years of research and development plus more years of validation studies and beta test users went into developing Lumen. Lumen is a hand-held device that accurately measures your metabolism through the breath. It uses a CO2 sensor and flow meter to measure the CO2 concentration in your breath, indicating if your body is in carb or fat burn.“So, this ability to shift between them, it's not only good for athletic performance it's also improving our quality of life,” Michal says. “It enables us to enjoy life to our fullest potential. It's about longevity. It's about being able to achieve our goals, not having those mood swings. This is so much more than improving athletic performance.”Lumen has accumulated a metabolic measurement database with over 20m measurements. These insights have shown how lifestyle habits affect metabolism and the body more than previously thought possible. Listen on to learn how with just one breath in the morning, you can set your metabolism course for the day and then monitor it throughout the day.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://lumen.me, use code Asprey50 to get $50 off a Lumen deviceWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Experience the High Life with Infrared Therapy: https://higherdose.com and use code HUMAN10 for 10% off your entire purchase.Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Elo 20221h 6min

Mini-Episode: Cool Facts Friday #25

Mini-Episode: Cool Facts Friday #25

In this Episode of The Human Upgrade™...​Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Tattoos can help monitor your blood pressure Device that protects against head injuries Upgrading your avocado toastWays to manage the harmful aging-inflammation duo Pee recycling does the soil goodEPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/. Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Heinä 202212min

How to Fix Your Brain When It’s Tired, Wired and Slow – Matt Gallant & Mr. Noots : 961

How to Fix Your Brain When It’s Tired, Wired and Slow – Matt Gallant & Mr. Noots : 961

IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll find out why aging and stress are the major contributors to neurodegenerative diseases in your lifetime, what you can do to stave off the effects, and how you can kickstart your brain into functioning at a way higher level.You’ll also learn about:BDNF (Brain-Derived Neurotrophic Factor) and ways to increase itOptions for how you can support your brain’s neurogenesisHow certain mushrooms and collagen can be used to increase your cognitive function—so you can focus, concentrate and be more creativeHow customized nootropics can help you reach peak mental performance Matt Gallant keeps coming back on the show to introduce innovative supplements that work with your brain and body. We’ve talked about nootropics, psychobiotics, magnesium, enzymes, blood sugar, gut health and more. As co-founder of BiOptimizers, Matt makes important connections within body systems and finds unique ways to maximum human performance. After a personal health scare with his own brain, he’s turned his professional attention to hacking and upgrading the brain in as many ways as possible.Most people’s brains aren't at 100% due to many factors, he says, like lack of sleep, chronic high stress, an inadequate diet, and overuse of certain drugs and prescriptions.Mr. Noots, (scientist Mark Effinger) teamed up with Matt on this quest to support brain health and improve cognitive function. After a childhood exploring everything science, chemistry and physics, he joined the US Air Force and became an endurance athlete and bodybuilder. His life, like Matt’s, took an unexpected turn and he struggled with health issues. It took creative, performance-enhancing nutrition to get himself well. He’s now Chief Product Officer for the mind-enhancing compounds and stacks of nootropics at Nootopia and works side-by-side with Matt.Their newest product, CollaGenius, combines powerful mushroom extracts and collagen into a formula specifically to energize your brain and body. Collagen improves skin health, relieves joint issues, strengthens hair and nails, and prevents bone loss—and it also does your brain a lot of good. And here’s what the mushrooms do for you in the right amounts. That’s the key principle—the dose creates the effect. Lion’s Mane: Boosts BDNFChaga: A natural anti-inflammatory that supports immunityReishi: Alleviates stressCordyceps: Elevates athletic performance and maximizes brain health Together, Matt and Mr. Noots continue pushing limits and finding ways to make your brain operate at its highest capacity. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSGo to https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% off.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mineral-Rich Salt with Micronutrients: https://oryxdesertsalt.com, learn more at the website and purchase through Whole FoodsA Cleaner Nicotine Alternative: https://lucy.co, use promo code DAVE20 for 20% off your first order of pouches, gums or lozenges.Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Heinä 202258min

Psychedelic Upgrade: Finding the Right Dose & Approach – Dr. Phil Wolfson & Dr. Julie Holland : 960

Psychedelic Upgrade: Finding the Right Dose & Approach – Dr. Phil Wolfson & Dr. Julie Holland : 960

IN THIS EPISODE OF THE HUMAN UPGRADE™...…two psychiatric research pioneers open up about the benefits people experience from psychedelic treatments. From mental health conditions to crucial social connections, there’s a dose and approach that can work for you and with your own brain chemistry.Psychiatrist and psychotherapist Dr. Phil Wolfson, creator of Ketamine Assisted Psychotherapy, leads patients through psychedelic psychotherapy sessions, guiding them through their past and present in an open, altered state of mind. His invaluable work is the result of an intense, many-decades-long clinical practice. He focuses on new pathways for healing depression, PTSD, addiction and other conditions.“There’s really no right or wrong with psychedelics,” Dr. Wolfson says. “It’s about how do we integrate our lives and relationship in this very difficult time with people and in our beings, and what practices we bring to this whole thing. So, it’s not just about substances.” Psychiatrist and psychopharmacologist Dr. Julie Holland explains in her book, “Good Chemistry: The Science of Connection, From Soul to Psychedelics,” why you need connection, how you’ve lost it, and how you might find it again. She believes psychedelics can help. Taken under the direction of a trained psychiatrist, they can catalyze a connection with the self, nature, or the cosmos.Dr. Holland’s research—with a focus on the parasympathetic nervous system—dives into how you can “turn on” and “tune in” to the brain chemistry that supports connection. At the same time, you can tamp down the fight or flight mode that derails sleep, metabolism, libido and much more. She’s leading new understanding about how your behaviors are driven by the hormones and neurotransmitters that make up good (and bad) brain chemistry, including testosterone, estrogen, dopamine, serotonin and most crucially, oxytocin. If you liked this special episode with Phil and Julie, you’ll learn even more from listening to their full podcasts on these topics:Your Guide to Psychedelic Psychotherapy – Dr. Phil Wolfson with Dave Asprey – #770Psychedelics Offer New Solutions for Social Isolation – Dr. Julie Holland with Dave Asprey – #757WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Structure Water Molecules; Achieve Body/Brain Coherence: https://analemma-water.com, use code DAVE10 for 10% offComplete Brain Nutrition with Nootropics: https://neurohacker.com/dave, use code DAVE to score an extra 15% off Qualia MindHydrate with Electrolytes: https://DrinkLMNT.com/DAVE, get a FREE LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Heinä 202233min

How Intuition Can Lead You To Your Highest Self – Joy Martina : 959

How Intuition Can Lead You To Your Highest Self – Joy Martina : 959

IN THIS EPISODE OF THE HUMAN UPGRADE™...…Dave’s travels take him to Amsterdam where he talks with psychic psychologist Joy Martina about intuition, hypnosis and joyful learning. Here’s some of the “how-to’s” you’ll learn about in this episode:How to find the right hypnotist for youHow to identify three common misperceptions about hypnosisHow to tap into your own intuition and tune into your own wisdomHow to recognize your body’s kinesthetic channel How to learn through joyful and pleasurable experiencesHow to listen to your gut just as much as your brainHow to use your energy for goodHow to draw from the quantum field How to connect to your highest potentialHo to create big change in your lifeHow to tune into your environment How to recognize the benefit from staying stuck in old patterns and make a shiftHow to notice your triggers and react less to themHow to move from an emotionally charged attached position to a grounded, neutral state.After this episode, head into the podcast library for Joy’s previous conversation with Dave: Intuition is Not a Feeling – #574.About Joy Martina: Joy Martina, psychic psychologist and a channeler of Christallin Consciousness specializes in high-level intuitive intelligence training for entrepreneurs, business owners and celebrities. She is an author, the creator of the Christallin Oracle Training, a master hypnotist and trainer of trainers.Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discountMattress Temperature Tech:https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProBusiness Growth With SEO:https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Heinä 20221h 4min

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