Episode 254: 254. Empagliflozin For Heart Failure with Preserved Ejection Fraction- EMPEROR-Preserved
Hospitalization for heart failure occurred in 8.6% of patients in the empagliflozin group and 11.8% patients in the placebo group (hazard ratio, 0.71; 95% CI, 0.60 to 0.83)number needed to treat [NNT]...
8 Maalis 20248min
Episode 253: 253. EMPA-REG OUTCOME - Type 2 Diabetes and Empagliflozin- How Much Money To Save How Many People?
EMPA-REG OUTCOME back in 2015 this was the first SGLT2 trial to set the world on fire with Primary Outcome: death from cardiovascular causes: NNT 46 per 3.1 yrs (at $600 a month, 1 million dollars per...
7 Maalis 202410min
Episode 252: 252. After Admission to the ICU How Many Patients Remain on a PPI?
Forty-two percent of patients had a PPI on their medication list without indication 8 weeks after discharge, and more than half of these patients still were using PPIs 1 year later. Compared with pro...
6 Maalis 20247min
Episode 251: 251. Does Weight/BMI Change DOAC Efficacy?
These results are reassuring for management of both underweight and overweight patients with AF. That said, I would still have reservations about prescribing DOACs in the small minority of patients wi...
5 Maalis 20245min
Episode 250: 250. Do Nurse Practitioners Prescribe More or Less Medications From the Beers List?
Nurse Practitioners prescribe medications off the beers list at the same rate at primary care physicians, hard to tell what this means for patient care and patient outcomes. https://www.acpjournals.or...
1 Maalis 20245min
Episode 249: 249. Is There A Way To Predict Your Risk Of Dementia?
Using the Brain Care Score seem to be effective in predicting the risk of dementia For participants under 50, each five-point higher BCS is associated with a 50% lower risk of dementia or stroke For p...
29 Helmi 20246min
Episode 248: 248. Should DAPT To Be Started >24hours After Minor Stroke OR High Risk TIA?
Even when starting DAPT within 72hours of symptom onset for individuals with minor stroke or TIA the benefit of DAPT for the first 21 days was still seen at 90 day follow up in the form of less recurr...
28 Helmi 20245min
Episode 247: 247. Should Patients With Cancer Be On Primary Prevention VTE Prophylaxis?
In those high risk patients -- usually with lung or GI cancer they did benefit from primary prevention VTE prophalaxis with a NNT of 6-7 for VTE and death at 6 months. https://pubmed.ncbi.nlm.nih.gov/...
27 Helmi 20245min
