Episode 422 - Q&A with Robb and Nicki #15

It's that time again! We're back with Q&A #15.

Show Notes:

1. [1:15] Thoughts on kids care?

Rich says:

Hi Rob,

I have 2 questions for you.

1. Is Palaeo a new term from your book Wired To Eat or did someone make a huge error?

2. What are your thought on kids care such as chiropractic treatment, massage, acupuncture etc when there are no obvious signs of issues but more for general maintenance as they're always throwing themselves around? My kids are 4 and 7.

Thanks in advance and genuinely love your work! Don't let spelling slow you down ;)

2. [5:56] NAD+, NR, NMN: Good or bad?

Ed says:

Hey Robb:

Got a question regarding NMN, Nicotinamide Riboside, NAD+, etc. I've read and listened to several peeps like Peter Attia and guests (e.g., David Sinclair from Harvard) tout the health benefits of NMN & NR, for those of us who want to stay young. This is all fine and dandy. (See https://peterattiamd.com/davidsinclair/) . I mean the number of people taking Tru Niagen is outstanding.... (me included).

Then Chris Masterjohn, who I love, indicated on one of his podcasts that we should be careful taking NR (and the like) as it effects methylation (a bad thing I think), with possible suggestion of having to take an exogenous form of glycine to balance the negative effect of taking large doses of NMN, NR products. https://chrismasterjohnphd.com/2018/07/26/careful-niacin-nicotinamide-riboside/

Been listening to you for years and always remember you getting a bit pissed off that your listeners wouldn't do some research for themselves before submitting vocational questions. Well I've tried to read & Listen to everything there is and can't clear the wheat from the chaff.

Maybe you can do a video or talk about this subject on your podcast?

Thanks,

Ed

3. [11:00] 22g Protein/Day MAX ??!

Kyle says:

I am so curious what your thoughts are on this book in general and more Dr. Gundry's theory that we should eat around 22g of protein MAX per day, and essentially around 60% carbs. Seems like a brilliant book full of testimonies but his theories on animal product enzymes and heart health seem to be a little off to me but I am no expert!

BTW - I am a huge fan and your work has impacted my life immensely. I am the COO for a company called The Perfect Workout. I believe we are both friends with Lawrence Neal from Corporate Warrior. Anyway, thanks for the opportunity to ask this! See you at PaleoFX in April.

4. [16:09] Extended fasting and muscle loss

Keith says:

Robb,

How are you coming on your piece regarding fasting, mTOR, and aging strategies? I ask because I'm at a point in my health journey where I've lost the ugly weight, refocused on gaining muscle mass, and would now like to shed a little bit more fat to reveal the fruits of my labor. To do so, I've been planning on getting back to a strict ketogenic lifestyle including a moderately aggressive fasting regimen. This is the same strategy I implemented during my initial 70lb, 8-month weight loss that was largely inspired by the work of Jason Fung.

I know you don't necessarily agree with Dr. Fung's opinions on fasting being a largely muscle sparing venture--which is why I've been lurking in anticipation of your work on this topic. In my journey from 230lbs to 160lbs I took part in daily intermittent fasts, frequent 36-hour fasts, and several fasts of 70-100 hour duration. Based on this experience, I didn't encounter any noticeable effect on my strength or visible musculature--even as I got down to a modest body fat percentage in the mid-teens.

With that being said, I'm very interested in the specifics of your views on extended fasting as a potential tool for cutting fat while preserving muscle--specifically as it would relate to hypertrophy-focused resistance training goals. A discussion between you and Dr. Fung on this topic would make for one incredibly interesting podcast.

Thanks for your time and for all of your continued work. Your ability to interpret and convey complex topics is unsurpassed in this field.

5. [25:56] Ketones too high?

Rob says:

Hi Robb & Nicki, I've been really enjoying this Q&A podcast format. I have a question I'd like to hear your thoughts on regarding blood BHB testing.

I've been hearing many people in the field saying that the more fat/keto adapted you are, the lower your blood BHB tend to be due to increased metabolic efficiency. Personally, I've been doing keto for many years now, sensibly, following the targeted protein requirement 1st, then adding in fat for the remaining fuel (as my goal is weight maintenance, not weight loss). I've never tested my blood BHB or urine ketones, just using the ketonix to test my breath ketones, which always shows that I'm in ketosis. Recently, just for curiosity's sake, I've got my hands on blood BHB testing, and my fasted morning readings average between 1.5-2.0mmol. Plus my recent urine test also shows elevated ketones (60mg/dL), which I wasn't expecting as I thought urine ketones are only present in the beginning phase of the diet. So now I'm wondering, is this normal/desirable or too high for someone who's been doing keto for years? Does this mean that I'm still not metabolically efficient after all these years?

I know you always prioritise how one looks, feels & performs, still I can't help but wonder, especially since the concept of "the higher the ketones the better" has never made much sense to me. So, yes, to put it simply, I'm asking is my ketones too high? Thank you both for your great work & your time!

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