The Methylene Blue Episode | Solo Biohacking Masterclass  : 1366

The Methylene Blue Episode | Solo Biohacking Masterclass : 1366

Methylene blue is one of the most misunderstood compounds in biohacking, yet it can upgrade your energy, mood, memory, and cellular resilience when you use it the right way. We are back again with another solo masterclass, and this one breaks down how to use methylene blue as a precision tool for brain optimization, longevity, and human performance while avoiding the dosing mistakes that create jitteriness, sleep disruption, or dangerous interactions.


Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR


Host Dave Asprey guides you through more than a century of research on methylene blue. He has been hacking this compound since the early 2000s and brings deep insight into mitochondria, neuroplasticity, metabolism, supplements, fasting, red light, ketosis, nootropics, and functional medicine. You will learn how methylene blue works inside the cell, how it improves electron transport, and why it appears in neurology, psychiatry, and anti aging research at the same time. This episode shows you how to test your own dose, how to stack it with light and ketosis for maximum effect, and how to avoid serotonin syndrome or sleep disruption.


Methylene blue also touches nearly every major system that biohackers care about, which is why this solo masterclass shows you how it interacts with mitochondria, neuroplasticity, metabolism, sleep optimization, and long term anti aging pathways. You will hear how it influences redox balance, ATP production, brain optimization, and stress resilience, and how it behaves when combined with ketosis, fasting, creatine, NAD boosters, red light therapy, or other nootropics. Host Dave Asprey explains why methylene blue pairs well with certain supplements but clashes with psychedelics or SSRI medications, how it fits into functional medicine protocols for mitochondrial repair, and how to use data and wearable tracking to dial in your response. This episode gives you a complete framework to evaluate whether methylene blue belongs in your personal longevity strategy and how to use it with precision instead of guesswork.


You’ll Learn:

• Why methylene blue acts like mitochondrial jumper cables and when it improves energy and mood

• The exact signs that your dose is too strong, too weak, or in the Goldilocks zone

• How methylene blue interacts with neuroplasticity, memory circuits, and cognitive resilience

• Why psychedelics, SSRIs, and MAO inhibitors can create dangerous serotonin interactions

• How to pair methylene blue with red light therapy, ketosis, creatine, fasting, or NAD boosters

• The link between mitochondrial health, fertility, libido, and long term anti aging strategies

• How to track sleep optimization, HRV, and performance signals to dial in your personal protocol

• The difference between aquarium grade dye and pharmaceutical grade formulations

• Why genetic testing for G6PD deficiency is essential before higher dose experimentation


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: methylene blue dosing, mitochondrial electron transport, Complex IV cytochrome c oxidase, redox cycling, MAO inhibition, serotonin syndrome risk, G6PD deficiency caution, neuroplasticity enhancement, dendritic spine density, mitochondrial stress adaptation, red light therapy stacking, cognitive performance optimization, ketone supported ATP production, nitric oxide independent focus boost, mitochondrial bottleneck repair, pharmaceutical grade methylene blue, sleep disruption signals, biohacking fertility support, oxidative stress buffering, functional medicine mitochondria repair


Thank you to our sponsors!

-BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle.

-fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.

-Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.


Resources:

• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.

• Danger Coffee: https://dangercoffee.com/discount/dave15

• My Daily Supplements: SuppGrade Labs (15% Off)

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 — Trailer

1:25 — Introduction

4:51 — History of methylene blue

7:38 — How methylene blue works

14:05 — Safety

17:53 — Dosing and timing guidelines

20:41 — Combining with red light therapy

22:41 — Quality and sourcing

23:17 — Dosing protocols

25:24 — Longevity and fertility effects

29:24 — Stacking options

32:10 — Common questions and FAQs

33:40 — Future research and wrap up

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1423)

#114 Marc David Hacks into the Psychology of Eating

#114 Marc David Hacks into the Psychology of Eating

Bestselling author and founder of the Institute for the Psychology of Eating, Marc David has made it his life’s work to help people do exactly what they say they want to do. On this episode of Bulletproof Radio, Marc goes deep into the psychology of eating and explains some of the easiest ways to hack your nutrition and perform better when you eat with integrity. You’ll discover why Marc says: “You cannot be a food addict,” along with how to make sense out of trauma, why the obesity paradox is a black eye in the face of science, how potato chip companies are capitalizing on our dental aggression habits, and a ton more!     Marc David is the Founder of the Institute for the Psychology of Eating, a leading visionary, teacher and consultant in Nutritional Psychology, and the author of the classic and bestselling books Nourishing Wisdom and The Slow Down Diet.  His work has been featured on CNN, NBC and numerous media outlets. The Institute for the Psychology of Eating is the world’s only teaching organization dedicated to a forward thinking, positive, holistic approach to nutritional psychology. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Huhti 20141h 2min

#113 Dr. Cate Shanahan and Bulletproofing the NBA

#113 Dr. Cate Shanahan and Bulletproofing the NBA

Dr. Cate Shanahan is using Bulletproof Diet principles to help pro athletes perform better. On this episode of Bulletproof Radio, physician, author, and LA Lakers Nutrition Director, Dr. Shanahan, talks how she transforms the diets of NBA stars like Dwight Howard and gets them to exchange nachos for charcuterie - one step at a time. Also hear Cate explain gluten on a molecular level and she makes a powerful argument for why consuming vegetable oil is like eating radiation. The show also includes information on: sugar addiction, milk proteins, and the benefits of eating, “meat on the bone”.     In addition to her thriving Napa Valley medical practice, Cate Shanahan, MD is Nutrition Director of the Los Angeles Lakers PRO Nutrition program. Before attending Robert Wood Johnson Medical School and specialty training at University of Arizona’s Family and Community Medicine, she studied genetics and biochemistry at Cornell. Her background enabled her to recognize the flaws in mainstream nutrition theories and fill in the gaps in most popular diets. She has worked with patients to achieve lasting weight loss, optimal sports performance, and elimination of medication dependence through a systematic approach. Like Dr. Cate on Facebook!  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

15 Huhti 201454min

#112 AJ Jacobs on His Life as an Experiment

#112 AJ Jacobs on His Life as an Experiment

Bestselling author and renowned NYC journalist, AJ Jacobs is a living, breathing experiment. On this episode of Bulletproof Radio, AJ reveals his methods behind hacking into (what he calls) the three domains of self-improvement. Jacobs talks about his quest to become the smartest person, what happened when he lived (quite literally) according to the Bible, and his humble quest for bodily perfection. Also catch tips on how to act your way into a new way of thinking. Enjoy!     A.J. Jacobs is an author, journalist, lecturer and human guinea pig. He has written four New York Times bestsellers that combine memoir, science, humor and a dash of self-help. He is also editor at large at Esquire magazine, a commentator on NPR and a columnist for Mental Floss magazine. His first book is called The Know-It-All: One Man’s Humble Quest to Become the Smartest Person in the World (Simon & Schuster, 2004). The memoir — which spent two months on the New York Times bestseller list — chronicles the 18 months Jacobs spent reading the entire Encyclopedia Britannica in a quest to learn everything in the world. It was praised by Time magazine, Newsweek, Vanity Fair, USA Today, Janet Maslin in the New York Times and AJ’s uncle Henry on Amazon.com. Follow him on Twitter @ajjacobs! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

11 Huhti 201448min

#111 Olympian Bree Schaaf talks Staying Bulletproof at Sochi

#111 Olympian Bree Schaaf talks Staying Bulletproof at Sochi

Olympian turned NBC analyst, Bree Schaaf talks staying Bulletproof while at the Sochi Olympics last month. Bree has been competing in sliding sports for the past 12 years. Just now back from Russia, Bree’s on Bulletproof Radio to discuss skeleton bobsled racing, her kickass routine for high performance, how she recovered from hip surgery, selenium toxicity, and more. Hear about how she didn’t let even the TSA keep her from eating a Bulletproof Diet during the games.     The former Portland State University Volleyball player spent her first five years on ice as a skeleton athlete before becoming a bobsled pilot.  Schaaf has earned 13 top-10 finishes on the World Cup circuit and finished fifth with brakeman Emily Azevedo at the Vancouver 2010 Olympic Winter Games. Schaaf is the first American female to compete in both a Skeleton World Championships as well as Bobsled World Championships.   Coming up just short at Olympic Trials this year, Schaaf not only be attended the Sochi 2014 Olympics as alternate, but made her NBC Olympics broadcast debut as a skeleton analyst and sliding sports correspondent.     ·           0:10 – Cool Fact of the Day! ·           0:30 – Welcome Bree Schaff ·           1:01 – What is skeleton? ·           3:57 – Traveling to Russia with butter and MCT ·           8:25 – Bree’s routine for high performance ·         10:50 – Hip surgery recovery and Bulletproof ·         14:05 – Finding glutes under the “lady fat” ·         14:35 – Bio-hacking menstrual cycle ·         18:00 – Testosterone envy ·         19:10 – Competitive drive ·         23:30 – Karaoke flow state ·         26:30 – Cholesterol ·         27:00 – Selenium toxicity ·         29:40 – Mental training and meditation   ·         39:05 – Top three recommendations for kicking more ass and being Bulletproof! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

8 Huhti 201445min

#110 CrossFit Master Shana Alverson Makes Strong The New Skinny

#110 CrossFit Master Shana Alverson Makes Strong The New Skinny

One of the 50 fittest women in the world comes on Bulletproof Radio to talk about how strong is the new skinny and how she became a major player in the CrossFit community. On this episode of Bulletproof Radio you’ll get a look inside the mind of a real CrossFit master and she’s sassy too. Alverson talks about her strict adherence to a Paleo diet, her thoughts on women and ketosis, and if she thinks it’s okay to do CrossFit while pregnant. Get the show below!     Shana Alvesrson owns Crossfit East Decatur in Georgia. She is a level 1 Certified CrossFit trainer as well as a Level I CrossFit Running & Endurance Certified. Shana also trains in CrossFit Olympic lifting, movement & mobility, gymnastics, and Crossfit kids. Her passion for the gym began at 15 after discovering how nutrition and exercise elevated her mood. She has been teaching people how to exercise since 1995, and in 2007 began her CrossFit training career. Catch her kicking ass a CrossFit East Decatur and on Twitter @ShanaAlverson. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Huhti 201441min

#109 Steven Kotler and The Rise of Superman

#109 Steven Kotler and The Rise of Superman

Have you ever experienced a flow state? It’s the superhuman state of high performance when everything is in-sync and you’re kicking ass at life? Bestselling author of The Rise of Superman, Steven Kotler, will teach you how to find your flow state and stay there. In this episode of Bulletproof Radio, Kotler breaks down the 3 psychological conditions for flow state, the 4 stages of flow, and how to turn it on and off. Steven also tells a great story about his own flow state experiences as a writer, his battle with Lyme disease, and discusses, The Flow Genome Project.     Steven Kotler is a New York Times bestselling author, award-winning journalist, and co-founder and director of research for the Flow Genome Project. His books include The Rise of Superman, Abundance, A Small, Furry Prayer, West of Jesus, and The Angle Quickest for Flight. His work has been translated into thirty languages and his articles have appeared in more than seventy publications, including the New York Times Magazine, Atlantic Monthly, Wired, and Forbes. You can find him online at stevenkotler.com or writing Far Frontiers, a blog for Forbes.com: www.forbes.com/sites/stevenkotler. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Huhti 20141h

#108 Dr. Sara Gottfried – The Hormone Cure

#108 Dr. Sara Gottfried – The Hormone Cure

Owning your hormonal health is crucial to performance, and this goes for all the sexes. M.D. and bestselling author of “The Hormone Cure,” Dr. Sara Gottfried joins Bulletproof Radio to underscore the importance of leveraging hormones and how to uncover the velvet vulva. Dr. Sara relies on results-based data and her own practice as a physician to define her theory on why women often struggle on high-fat diets and often take a dive off a hormonal cliff. On this show you’ll learn about monitoring your brain chemical three-some, feeding the gut bacteria you want, and how birth control pills can affect sexual attraction.     Dr. Sara Gottfried M.D. is a Harvard-educated physician, speaker, yoga teacher, wife, mom of two daughters, and author of the New York Times bestselling book, The Hormone Cure: Reclaim Balance, Sleep, Sex Drive, and Vitality with The Gottfried Protocol (Simon & Schuster, 2014). She’s also a board-certified gynecologist and the creator of an awesome new online program called Mission Ignition: The Energy Cure. For the past 20 years, Dr. Gottfried has been dedicated to helping women feel back home in their bodies. Like Sara on Facebook! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Maalis 201452min

#107 Pedram Shojai on Vitality and Origins – Podcast

#107 Pedram Shojai on Vitality and Origins – Podcast

“Follow the bread crumbs...”   Many people would say that the human race is entering an era of awakening. Whether that be in mind, body, spirit, or all three there is a good chance that if you’re reading this, you’d agree – or at least you’re interested. Talented physician and documentary filmmaker, Pedram Shojai, is on the show to discuss the concepts behind his two films, Vitality and Origins, and why he’s in the business of waking up zombies. On the show you’ll discover Pedram’s take on what we should be eating, how to make everything you do count the most, and why he’s trying to win the war against healthcare propaganda. Pedram is a great example of how to balance science and mysticism. After all, any good science warrants investigation. Please enjoy!     Pedram Shojai is former Taoist monk and an accomplished physician of Chinese medicine. He is the founder of Well.org, an author, and most recently a documentary filmmaker. After studying biology at UCLA he had a series of profound mystical experiences that drew him to the Eastern esoteric arts. He received a Master’s in Oriental Medicine from Emperor’s College and then his own OMD from the Pan-American University. Pedram has studied Kung Fu, Tai Chi, Qi Gong, Yoga, Meditation, and medicine diligently for the past 20 years, and aims to help people wake up from their zombie haze and live their lives fully. Follow him on Twitter @taoistpath!  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Maalis 201445min

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