10-Minute Biohacking News Update : 1367

10-Minute Biohacking News Update : 1367

This episode covers:


Nano CBD Pain Relief Without Cognitive Side Effects


A new nano-micelle formulation of CBD called CBD-IN delivers fast, non-addictive pain relief in mice without memory issues, motor impairment or the usual cannabinoid “fog.” Because it crosses the blood brain barrier and directly targets hyperactive pain circuits, it sidesteps many opioid-type drawbacks. Dave explains why precision-designed cannabinoids could reshape chronic pain treatment and longevity support.

Source: https://www.sciencedaily.com/releases/2025/11/251117095652.htm



Moderate Calorie Restriction Slows Biological Aging


A long-term trial from the National Institute on Aging found that cutting calories by about 12% over two years slowed the pace of aging — measured by methylation clocks and metabolic markers — in lean and mildly overweight adults alike. Dave breaks down why small, manageable dietary tweaks can deliver big longevity gains, without crash dieting or extreme fasting.

Source: https://www.nia.nih.gov/news/cutting-calories-may-slow-pace-aging-healthy-adults


FDA Approves AI-Guided Robotic Surgery Trials for Alzheimer’s


The U.S. Food and Drug Administration (FDA) has granted IDE approval for the first robotic microsurgical study targeting early stage Alzheimer’s disease using AI and deep imaging. The trial uses adaptive robotics to target deep brain lymphatic pathways, potentially clearing amyloid/tau deposits with surgical precision. Dave explains why this signals a new era in neurodegeneration – moving from drug-only to machine-assisted brain repair.

Source: https://www.mmimicro.com/ide-approval-for-first-robotic-microsurgery-alzheimers-study/


Antibiotic Reprograms Gut Bacteria to Produce Anti-Aging Molecules


Researchers demonstrated that the veterinary antibiotic cephaloridine can reprogram gut microbes to secrete colanic acid — a molecule linked to better mitochondrial health, reduced gut permeability and improved cholesterol/insulin balance in mice. Dave explores how this could evolve into a pipeline of engineered probiotics that act as internal “longevity factories.”

Source: https://newatlas.com/aging/antibiotic-longevity-microbiome/ (link remains unchanged)


Klotho: The Longevity Protein Nears Clinical Reality


The longevity protein Klotho, known for clearing toxic by-products, calming inflammation and protecting brain/organ networks, is now advancing toward human trials via injectables, oral formats and gene therapy. Dave explains why Klotho is shaping up as a foundational target for next-gen age-reversal strategies and stacking protocols.

Source: https://investingnews.com/longevity-focused-health-fueling-u-s-anti-aging-products-market-projected-to-reach-27-billion-by-2033/ (link remains unchanged)


All source links provided for easy reference to the original reporting and research above.


This episode is essential listening for fans of biohacking, human performance, functional medicine and longevity who want practical tools from Host ­Dave Asprey and the latest breakthroughs shaping the future of health.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade gives you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio only) and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: nano CBD, CBD-IN, pain relief research, non opioid pain therapies, chronic pain and aging, caloric restriction aging, methylation clocks, metabolic resilience, AI robotics, Alzheimer’s microsurgery, neurotech advancement, microbiome engineering, colanic acid, longevity probiotics, mitochondrial support, Klotho protein, anti aging gene therapy, cellular rejuvenation, longevity news, biohacking updates


Thank you to our sponsors!



Resources:

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• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

0:00 — Intro

0:19 — Story 1: Nano CBD for Pain Relief

1:53 — Story 2: Caloric Restriction and Aging

3:20 — Story 3: AI Robotic Surgery for Alzheimer’s

4:50 — Story 4: Microbiome Reprogramming

6:05 — Substack Announcement

7:04 — Story 5: Klotho Longevity Protein

8:39 — Weekly Homework

9:31 — Outro

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Jaksot(1430)

9BC Mini Episode: Tapping Into Your Brain with Patrick Porter, Ph.D. : 1059

9BC Mini Episode: Tapping Into Your Brain with Patrick Porter, Ph.D. : 1059

We're previewing the 9th annual Biohacking Conference in Orlando Florida (June 22 - 24) on The Human Upgrade!Patrick K. Porter, PhD has dedicated his life to studying neuropsychology. For years it was believed that we have a set number of brain cells, that our intelligence quotient is fixed, and that our brains do not change. Dr. Porter’s clinical experience and research told a different story, revealing that the human brain is, in fact, plastic, making it capable of change, improvement, and expansion. Patrick’s discoveries led him to develop the BrainTap headset, sparking incredible transformation for thousands of people. In 2014, with the emergence of the Apple and Android mobile platforms, he saw the opportunity to impact millions more by bringing this technology to an app. Thus, the brain fitness company – BrainTap – was born.BrainTap has proven that your brain can be retrained to operate at its best and that it’s never too late to tap into your brain’s fullest potential. With its state-of-the-art headset and a suite of more than 1800 sessions that range across dozens of desired life outcomes, the company has made great strides in revitalizing the mental clarity, confidence, and energy of extraordinary individuals worldwide.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://braintap.com/dave9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Kesä 202316min

Stem Cell Therapy and Personal Stem Cell Banking with Sean Berman and Kevin Ferber  : 1058

Stem Cell Therapy and Personal Stem Cell Banking with Sean Berman and Kevin Ferber : 1058

America is back on the map as a global leader in stem cell technology, thanks in huge part to these two FDA-conquering innovators. Sean Berman and Kevin Ferber talk about the past, present, and future of stem cell therapy – and where, why, and how to bank your own healthy cells ASAP. Watch this episode on YouTube.Find all the links and resources in the show notes.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!American Cell Technology: https://americancelltechnology.com/dave/California Stem Cell Treatment Center: http://CaliforniaStemCellTreatmentCenter.comBioHacking Conference 2023: https://americancelltechnology.com/biohacking2023/California Stem Cell Treatment Center: http://CaliforniaStemCellTreatmentCenter.comSleep Solutions for High Performance: https://sleepbreakthrough.com/dave, use code DAVE10 to get an extra 10% off 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

8 Kesä 20231h 11min

BioQuantum Skincare with Jewel Arnes : 1057

BioQuantum Skincare with Jewel Arnes : 1057

Today’s show gets into DNA, genetic codes, consciousness, energy, and BioQuantum Skincare. Jewels Arnes comes on today's show to make sense of it all and make some cool connections between those things for you. Her expertise includes three decades of energy medicine, vibrational healing, and intensive consciousness work. She pairs that work with creating tangible products, like the BioQuantum Skincare Technology, the Scalar Cosmetic Line, and an EvoStar Quantum App.In this episode, you’re going to learn how BioQuantum Skincare enhances DNA & telomere health, how to use the products to treat skin conditions, how to advance the consciousness of the products, and how to advance skin health with no products at all.There’ll be some discussion of breaking quantum physics in here, too.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Website: https://bioquantumskincare.com/DAVEJewels Arnes Talks Breaking Quantum PhysicsInstagram: https://www.instagram.com/bioquantumskincare/Facebook: https://www.facebook.com/bioquantumskincareYouTube: https://www.youtube.com/@bioquantumskincareJewels Arnes: https://jewelsarnes.comActivate Evolution: https://activateevolution.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Kesä 20231h

Upgrade Spotlight: Redefining Wellness with Topical Glutathione: A Health Revolution with Nayan Patel , PharmD  : 1056

Upgrade Spotlight: Redefining Wellness with Topical Glutathione: A Health Revolution with Nayan Patel , PharmD : 1056

Nayan Patel, PharmD recently published his first comprehensive book, “The Glutathione Revolution: Fight Disease, Slow Aging & Increase Energy.” After 14 years of clinical research on the master antioxidant, glutathione, Dr. Patel finally shares how powerful and essential glutathione is to the body’s detox system. He speaks about the various benefits it has with slowing the aging process down, and explains how you can increase your levels naturally. Dr. Patel is a firm believer in providing the body with tools it needs to defend itself and promote a healthy lifestyle that fits the pace of the modern world. Nayan Patel, Pharm.D is globally regarded as the foremost go-to expert on absorbable forms of glutathione, and holds the only patent on transdermal glutathione.Along with traveling the world educating practitioners on advanced biochemistry and anti-aging science, Dr. Patel also serves as adjunct faculty at the University Of Southern California School Of Pharmacy where he is also an alumnus.9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Kesä 202330min

Upgrade Spotlight: Unlocking the Secrets of Water Energy, Frequency & Vibration - Mario Brainovic : 1055

Upgrade Spotlight: Unlocking the Secrets of Water Energy, Frequency & Vibration - Mario Brainovic : 1055

Mario Brainovic is an expert in the science of water, specifically focusing on its ability to transmit energy, frequency, and vibration. With a wealth of knowledge and extensive research under his belt, Mario has dedicated his work to understanding the profound changes that can occur in our biology when we consume water that has been treated with the right frequencies.As the CEO of Analemma, Mario has developed a unique approach to creating positively charged water that can boost our physiology and overall health. This friendly and passionate water enthusiast is always eager to share new findings and discoveries to help others optimize their energy levels.Find all the links and resources in the show notes. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discountBiohack and advance your skincare to the next level with https://bioquantumskincare.com/ use code DAVE22 for 22% OFF9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Touko 202355min

The Secrets to Creating Your Own Happy, Healthy Life - Jason Wachob : 1054

The Secrets to Creating Your Own Happy, Healthy Life - Jason Wachob : 1054

Looking for a more balanced and fulfilling life? A life where you prioritize your own self-awareness and holistic wellness? Well, Jason Wachob has the solution to help you achieve optimal health and vitality through a mindful and prioritized approach to your well-being.In this episode, Jason will teach you how to fortify your emotional well-being by fostering social connections and community ties. Enhance the environment through the adoption of regenerative agriculture and sustainable farming techniques. Discover happiness and significance by focusing on the crucial aspects of life. Fine-tune your diet by paying attention to your body's unique needs for optimal health.Watch this episode on YouTube.Find all the links and resources in the show notes. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Shield Yourself from EMFs: https://quantumupgrade.io, use code DAVE to get a two-week free trialSleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to save.9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Touko 202348min

Unlock Your Limitless Potential & Unleash Your Inner Peace - Genpo Roshi : 1053

Unlock Your Limitless Potential & Unleash Your Inner Peace - Genpo Roshi : 1053

Genpo Roshi, the respected spiritual leader with a wealth of experience in Zen practice and personal growth, is back in this legacy upgrade episode.In this episode, you will uncover the wisdom behind Genpo Roshi's views on Zen and meditation on your path towards enlightenment. Master the skills of non-judgmental relaxation techniques to enhance inner peace. Combine the power of deep relaxation, Big Mind process, and koan practice for a holistic meditation experience. Discover the keys to lasting happiness by embracing freedom and giving up the pursuit of external factors.Listen in to learn how to cultivate personal growth through self-care practices, valuable introspection, and fostering healthy relationships.Get all the links and resources in the show notes.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Get your tickets to the 9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

19 Touko 202339min

Redefine Your Reality & Unveil the Secrets of Your Conscious Mind - Philip Goff & Anil Seth : 1052

Redefine Your Reality & Unveil the Secrets of Your Conscious Mind - Philip Goff & Anil Seth : 1052

What if everything you perceive is just a construction of your brain? In this episode, Anil Seth and Philip Goff explain how our perception of reality is a product of our minds and how it can be manipulated. They also delve into the implications of these findings, and take a dark turn, leaving you questioning everything you thought you knew about yourself and the world around you.Get ready to dive into the fascinating world of perception and consciousness with our guests Philip Goff and Anil Seth. Together, they're here to unravel the mysteries of how our brains construct our conscious reality.Tune in to explore panpsychism and its fascinating connection between consciousness and matter. Gain an understanding of how our brains craft our conscious reality through the intricate process of perception. Acknowledge the limitations of traditional views on consciousness while considering the perks of embracing panpsychism. Master the art of training perception for practical applications rather than perfect accuracy. And most importantly, discover insightful tools for probing consciousness, such as meditation and introspection.Get all the links and resources in the show notes.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Could this Saturated Fat be the missing link in longevity research? Go to https://fatty15.com and use code DAVE15 to save $15.Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% offElectrolytes That Taste Good With Zero Sugar Hydration: https://drinklmnt.com/dave, get a FREE LMNT Sample PackSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Touko 202349min

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