Dec 19 2025 This Week in Cardiology

Dec 19 2025 This Week in Cardiology

The MI paradox of risk scores, the CELEBRATE trial of a new subcutaneous glycoprotein IIb/IIIA inhibitor (with its funny endpoint), the SURPASS CVOT trial, and the bad story of andexanet alfa are the topics John Mandrola, MD, discusses in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I What do risk scores mean for individuals? Or perhaps a better question: Is a first MI preventable?

  • Limitations of Screening in Predicting First MI https://www.jacc.org/doi/10.1016/j.jacadv.2025.102361
  • Sudden Death Due to Cardiac Arrhythmias https://www.nejm.org/doi/abs/10.1056/NEJMra000650
  • UMC Amsterdam group (EHJ) https://academic.oup.com/eurheartj/article/46/38/3762/8181058

II CELEBRATE Trial

  • CELEBRATE Trial https://evidence.nejm.org/doi/full/10.1056/EVIDoa2500268

III SURPASS CVOT Trial Published

Aug 01, 2025 This Week in Cardiology Podcast

https://www.medscape.com/viewarticle/1002781

  • SURPASS-CVOT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2505928
  • REWIND Trial 10.1016/S0140-6736(19)31149-3 External Link

IV FDA Pulls Andexanet Alfa From the Market

  • ANNEXA 4 https://www.nejm.org/doi/10.1056/NEJMoa1814051
  • ANNEXA I https://www.nejm.org/doi/full/10.1056/NEJMoa2313040
  • Richard Buka Tweet https://x.com/richardbuka/status/2001045834050216327?s=20

V Mandrola's Top Cardiovascular Stories of 2025

https://www.medscape.com/viewarticle/mandrolas-top-10-cardiovascular-stories-2025-2025a1000yuh

You may also like:

The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact news@medscape.net

Episoder(402)

Aug 22 2025 This Week in Cardiology

Aug 22 2025 This Week in Cardiology

John Mandrola discusses conduction system pacing vs standard pacing, withdrawing HF meds when AF is corrected and patient selection in LAAO. This podcast is intended for healthcare professionals only....

22 Aug 202526min

Aug 15 2025 This Week in Cardiology

Aug 15 2025 This Week in Cardiology

Big new hypertension guidelines, ultraprocessed foods, coronary sinus reduction and evidence-based medicine, and more news on pulsed field ablation for atrial fibrillation are the topics John Mandrola...

15 Aug 202523min

Aug 08 2025 This Week in Cardiology

Aug 08 2025 This Week in Cardiology

Listener feedback on SURPASS CVOT, AF ablation and the limits of meta-analyses, a Watchman alert from FDA, and oral anticoagulation choices in elderly patients are discussed by John Mandola, MD, in th...

8 Aug 202531min

Aug 01 2025 This Week in Cardiology

Aug 01 2025 This Week in Cardiology

Exercise and CV outcomes, aldosterone modulation, AI for ECG reading, GLP-1 comparisons, end-of-life decisions, and another well-meaning policy that caused harm in veterans are discussed by John Mandr...

1 Aug 202530min

July 25 2025 This Week in Cardiology

July 25 2025 This Week in Cardiology

The VENTOUX study of endurance athletes, the 10,000 step myth was not busted, rate vs rhythm control for AF, and GLP1 drugs and observational studies are the topics John Mandrola, MD, discusses in thi...

25 Jul 202531min

Jul 18 2025 This Week in Cardiology

Jul 18 2025 This Week in Cardiology

Finerenone, what not to consider when choosing treatment of AS, brain health after atrial fibrillation ablation, early rhythm control for AF, and Watchman reimbursement cuts are discussed by John Mand...

18 Jul 202532min

Jul 11 2025 This Week in Cardiology

Jul 11 2025 This Week in Cardiology

Approval of first-generation devices, the ticagrelor controversy, ICD longevity, the PRAGUE-25 trial (one of the most important trials of the year), and some thoughts on the end of EP as a profession ...

11 Jul 202526min

Jun 27 2025 This Week in Cardiology

Jun 27 2025 This Week in Cardiology

FDA approves triple-drug polypill, a change of opinion, a deep dive into invasive pulmonary embolism therapies, heart disease trends, and diabetes care is on fire are the topics John Mandrola, MD, dis...

27 Jun 202528min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
jss
rekommandert
forskningno
sinnsyn
tomprat-med-gunnar-tjomlid
rss-nysgjerrige-norge
villmarksliv
rss-paradigmepodden
liberal-halvtime
nevropodden
fjellsportpodden
kvinnehelsepodden
rss-inn-til-kjernen-med-sunniva-rose
diagnose
smart-forklart
psykopoden
tidlose-historier
rss-rekommandert