EPISODE 2: Spaceflight, Muscle Loss & Worms – How Microgravity Reshapes Biology

EPISODE 2: Spaceflight, Muscle Loss & Worms – How Microgravity Reshapes Biology

In this episode, we explore how microgravity affects muscle structure and function, using Caenorhabditis elegans as a model organism. Spaceflight-induced muscle atrophy is a major challenge for astronauts, and understanding the molecular and genetic mechanisms behind these changes is key to developing countermeasures.


This discussion is based on the review article:

“Advancing Insights into Microgravity-Induced Muscle Changes Using Caenorhabditis elegans as a Model Organism”

Beckett LJ, Williams PM, Toh LS, Hessel V, Gerstweiler L, Fisk I, Toronjo-Urquiza L, Chauhan VM. Published in npj Microgravity (2024).

📖 Read the full paper: ⁠https://doi.org/10.1038/s41526-024-00418-z⁠


🔬 Learn how C. elegans provides unique insights into metabolic changes, gene expression, and protein regulation during spaceflight, offering potential strategies to counteract muscle degradation.


🌍 Follow for more research-based discussions on nematodes, space biology, and biomedical science.


This podcast is generated with artificial intelligence and curated by Veeren. If you’d like your publication featured on the show, please get in touch.


📩 More info:

🔗 www.veerenchauhan.com

📧 veeren.chauhan@nottingham.ac.uk

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Episoder(53)

EPISODE 53: Worms on Pause

EPISODE 53: Worms on Pause

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EPISODE 52: Worms in Space: Microbiomes in a Capsule

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EPISODE 51: The Worm Behind the Wild

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EPISODE 50: Fed by Mum, Built by Ribosomes

EPISODE 50: Fed by Mum, Built by Ribosomes

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EPISODE 49: Glowing up the Worm Proteome

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EPISODE 48: Murder Mode: How a Worm Evolved the Urge to Kill

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6 Mai 14min

EPISODE 47: When Bacteria Fight Back: Bioplastic Kills the Worm

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Welcome to the next episode of the WOrM Podcast 🪱Today we’re talking about something unexpected.A bioplastic — something we usually think of as sustainable, useful, even beneficial —can kill a worm.⸻...

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EPISODE 46: Turning in Time: Neural Sequences in the Worm Brain

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