EPISODE 23: Magnetic Minds – Worms Reveal Brain-Wide Signals in Real Time

EPISODE 23: Magnetic Minds – Worms Reveal Brain-Wide Signals in Real Time

In this episode, we follow Caenorhabditis elegans into the magnetic field. Researchers have developed an elegant way to measure whole-brain neural activity in freely moving worms using a calcium-sensitive MRI contrast agent — a major step toward non-invasive brain mapping at the organism scale.


We explore:


  • How a genetically targeted MRI probe was used to detect calcium flux across the entire worm brain

  • The fusion of genetics, MRI physics, and behavioural tracking

  • Real-time measurements of brain dynamics during natural behaviour

  • How this technique opens the door to non-invasive neuroimaging in small model organisms

  • Implications for understanding how global brain states coordinate behaviour



📖 Based on the research article:

“Functional MRI of brain-wide activity in freely moving C. elegans”

Uday A. Ramalingam, Andrew M. Leifer, et al.

Published in Nature (2024)

🔗 https://doi.org/10.1038/s41586-024-08331-x



🎧 Subscribe to the WOrM Podcast for more full-organism innovations in imaging, neuroscience, and behaviour!


This podcast is generated with artificial intelligence and curated by Veeren. If you’d like your publication featured on the show, please get in touch.


📩 More info:

🔗 ⁠⁠www.veerenchauhan.com⁠⁠

📧 veeren.chauhan@nottingham.ac.uk

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(53)

EPISODE 53: Worms on Pause

EPISODE 53: Worms on Pause

Welcome to the next episode of the WOrM Podcast 🪱⏸️Today, we are talking about worms that appear to stop living—without dying.Researchers have identified a new, reversible state of suspended animatio...

5 Aug 26min

EPISODE 52: Worms in Space: Microbiomes in a Capsule

EPISODE 52: Worms in Space: Microbiomes in a Capsule

Welcome to the next episode of the WOrM Podcast 🪱🚀Today, we are looking at NemaCapsules: a new microfluidic system designed to study how host genetics and the gut microbiome influence C. elegans hea...

29 Jul 21min

EPISODE 51: The Worm Behind the Wild

EPISODE 51: The Worm Behind the Wild

Welcome to the next episode of the WOrM Podcast 🪱Today we’re looking at a review with a bold idea.Can a tiny nematode help us protect fish, amphibians, reptiles and insects from an increasingly chall...

22 Jul 16min

EPISODE 50: Fed by Mum, Built by Ribosomes

EPISODE 50: Fed by Mum, Built by Ribosomes

Welcome to the next episode of the WOrM Podcast 🪱Today we’re talking about inheritance.Not DNA.Not small RNAs.Not epigenetics.But ribosomes.⸻🧬 The central ideaWhen mother worms experience dietary re...

15 Jul 20min

EPISODE 49: Glowing up the Worm Proteome

EPISODE 49: Glowing up the Worm Proteome

Welcome to the next episode of the WOrM Podcast 🪱Today we’re looking at a paper that doesn’t answer a biological question.Instead, it builds the tools to answer thousands of biological questions in t...

8 Jul 21min

EPISODE 48: Murder Mode: How a Worm Evolved the Urge to Kill

EPISODE 48: Murder Mode: How a Worm Evolved the Urge to Kill

Welcome to the next episode of the WOrM Podcast 🪱Today we're talking about a worm with teeth.And a nervous system that has been rewired — by evolution — to become aggressive.⸻🧬 The central ideaPrist...

6 Mai 14min

EPISODE 47: When Bacteria Fight Back: Bioplastic Kills the Worm

EPISODE 47: When Bacteria Fight Back: Bioplastic Kills the Worm

Welcome to the next episode of the WOrM Podcast 🪱Today we’re talking about something unexpected.A bioplastic — something we usually think of as sustainable, useful, even beneficial —can kill a worm.⸻...

29 Apr 21min

EPISODE 46: Turning in Time: Neural Sequences in the Worm Brain

EPISODE 46: Turning in Time: Neural Sequences in the Worm Brain

Welcome to the next episode of the WOrM Podcast 🪱Today we’re looking at something deceptively simple: a turn.But not just that a worm turns —how the brain decides to do it.⸻🧬 The central ideaTurning...

22 Apr 19min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
abels-tarn
liberal-halvtime
romkapsel
jss
rekommandert
vett-og-vitenskap-med-gaute-einevoll
sinnsyn
dekodet-2
villmarksliv
fjellsportpodden
rss-rekommandert
tomprat-med-gunnar-tjomlid
rss-inn-til-kjernen-med-sunniva-rose
rss-nysgjerrige-norge
rss-overskuddsliv
diagnose
abid-nadia-skyld-og-skam
forskningno