Life Uncut22 Mai 2025

PCOS - Polycystic Ovarian Syndrome. Fertility, Weight and ‘Balancing Hormones.’ Uncut with Dr Izzy Smith

Polycystic ovarian syndrome or PCOS is a condition that affects 1 in 9 women. The symptoms include things like pimples, increased body hair, thinning of the hair on our head, missed periods (and the flow on effects that affect fertility and build up of the endometrium which is a risk factor for endometrial cancer), increased risk of developing metabolic syndrome (insulin resistance, diabetes and cardiovascular syndrome) and increased risk of mental health conditions. PCOS sucks! (You can probably tell who from the team is writing these episode notes). Keeshia was diagnosed with PCOS about 4 years ago so today Keeshia and Britt are joined by the wonderful Dr Izzy Smith!

Dr Izzy Smith is an endocrinologist who has special training in women’s health (PCOS, amenorrhea, menopause transition) thyroid dysfunction, eating disorders and athlete health.

In today’s chat we speak about:

The large variety of symptoms & why it’s often misdiagnosed
What’s going on with our hormones
PCOS and fertility
Lean PCOS v Overweight PCOS
How insulin resistance develops
Weight management
Cortisol and stress
Treatment options for PCOS
What helps and what is marketing BS
Endocrine disruptors
Are weight loss medications an appropriate treatment for PCOS?

Find more from Dr Isobel Smith at her website

And her instagram

We referenced an episode about weight loss medications with Johann Hari that you can watch here.

Izzy also mentioned The Eco Well and the endocrine society website

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