Symposium | FLT3 mutations in AML: Types, prevalence, and clinical significance
AML Hub14 Jan

Symposium | FLT3 mutations in AML: Types, prevalence, and clinical significance

The AML Hub held a webinar on November 19, 2025, titled, “Understanding the differences between FLT3-ITD and -TKD mutations in AML: Implications for clinical practice.” Here, we share one of the presentations, by Jorge Sierra, Hospital de la Santa Creu i Sant Pau, Barcelona, ES, discussing the types, prevalence, and clinical significance of FLT3 mutations in acute myeloid leukemia (AML).


Sierra provided an overview of the role of FLT3-internal tandem duplication (ITD) and -tyrosine kinase domain (TKD) mutations in AML pathogenesis, and the differences in their molecular characteristics. He then discussed the prognostic value of FLT3-ITD and -TKD and concomitant mutations in patients with AML, and current risk stratification guidelines.


This educational resource is independently supported by Daiichi Sankyo. All content was developed by SES in collaboration with an expert steering committee. Funders were allowed no influence on the content of this resource.

Hosted on Acast. See acast.com/privacy for more information.

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(40)

Venetoclax combinations in mutant AML subtypes: IDH1/2

Venetoclax combinations in mutant AML subtypes: IDH1/2

During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the AML Hub spoke to Daniel Pollyea, University of Colorado School of Medicine, Aurora, US, about venetoclax combina...

25 Jan 20216min

Venetoclax combinations in mutant AML subtypes podcast: FLT3

Venetoclax combinations in mutant AML subtypes podcast: FLT3

During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the AML Hub spoke to Naval Daver, MD Anderson Cancer Center, Houston, US, about venetoclax combinations in patients ...

20 Jan 202112min

Introduction to a series of podcasts on the use of venetoclax combinations in mutation subtypes of AML

Introduction to a series of podcasts on the use of venetoclax combinations in mutation subtypes of AML

During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the AML Hub spoke to Courtney D. DiNardo, MD Anderson Cancer Center, Houston, US, about the use of venetoclax combin...

20 Jan 20218min

How close are we to offering treatment tailored to mutational profile?

How close are we to offering treatment tailored to mutational profile?

During the European School of Haematology (ESH) 2nd How to Diagnose and Treat: Acute Leukaemia meeting, the AML Hub spoke to Jorge Sierra, Hospital de la Santa Creu i Sant Pau, Barcelona, ES. In this ...

8 Jul 20205min

Approaches and emerging therapies for TP53 AML

Approaches and emerging therapies for TP53 AML

During the 25th Congress of the European Hematology Association (EHA), the AML Hub spoke to a member of our steering committee, Naval Daver, The University of Texas MD Anderson Cancer Center, Houston,...

1 Jul 202014min

How can we use the microbiome to improve cancer immunotherapy and alleviate side effect such as graft-versus-host-disease

How can we use the microbiome to improve cancer immunotherapy and alleviate side effect such as graft-versus-host-disease

During the American Association of Cancer Research (AACR) Virtual Annual Meeting I, the AML Hub was pleased to speak to Christine Spencer, Parker Institute for Cancer Immunotherapy, San-Francisco, US ...

24 Jun 202024min

Can CD47 antibody therapy be safely used for AML and MDS?

Can CD47 antibody therapy be safely used for AML and MDS?

During the 25th Congress of the European Hematology Association (EHA), the AML Hub hosted a discussion between David Sallman, Moffitt Cancer Center, Tampa, US, and Steering Committee Member Naval Dave...

22 Jun 202014min

How does the type of prior treatment affect the risk of therapy-related myeloid neoplasms?

How does the type of prior treatment affect the risk of therapy-related myeloid neoplasms?

During the American Society of Clinical Oncology (ASCO) Annual Meeting, Alexander Maurer from the AML Hub hosted a group discussion with Michael Ozga and Caner Saygin, both from The Ohio State Univers...

9 Jun 202020min

Populært innen Fakta

fastlegen
dine-penger-pengeradet
relasjonspodden-med-dora-thorhallsdottir-kjersti-idem
rss-bisarr-historie
foreldreradet
treningspodden
jakt-og-fiskepodden
rss-strid-de-norske-borgerkrigene
mikkels-paskenotter
rss-sunn-okonomi
rss-kunsten-a-leve
sinnsyn
hverdagspsyken
dopet
rss-kull
lederskap-nhhs-podkast-om-ledelse
fryktlos
hagespiren-podcast
gravid-uke-for-uke
hr-podden-2