Wilson & Moore on B Lymphocytes and eroding islet tolerance in type 1 diabetes, Mittendorfer on the effects of marked weight loss on postprandial glucose disposal in type 2 diabetes, plus "Sweet Talk" with Sir Stephen O'Rahilly

Wilson & Moore on B Lymphocytes and eroding islet tolerance in type 1 diabetes, Mittendorfer on the effects of marked weight loss on postprandial glucose disposal in type 2 diabetes, plus "Sweet Talk" with Sir Stephen O'Rahilly

Welcome to the February 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the February 2026 issue of Diabetes.

6:10 To discuss this issue's Paper of the Month, our hosts are joined by authors Christopher Wilson, PhD and Daniel J. Moore, MD, PhD, both of Vanderbilt University. Their article, "B Lymphocytes Impede Tregs to Erode Islet Tolerance in Type 1 Diabetes," is available for free at doi.org/10.2337/db25-0241.

37:05 Next, Darleen speaks with Bettina Mittendorfer, PhD. Dr. Mittendorfer is Senior Associate Dean for Research and Director of NextGen Precision Health, Clinical and Translational Science Unit at the University of Missouri and the lead author of "Effects of Marked Weight Loss Induced by Gastric Bypass Surgery or Low-Calorie Diet Alone on Postprandial Glucose Disposal in Type 2 Diabetes," available for free at doi.org/10.2337/db25-0737.

56:00 In the latest edition of "Sweet Talk," Kevin introduces Sir Stephen O'Rahilly, a clinical scientist at the University of Cambridge and past recipient of the American Diabetes Association's Banting Medal for Scientific Achievement. They discuss O'Rahilly's career, which reshaped scientists' understanding of metabolism and metabolic disease.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

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Episoder(36)

A Diabetes Symposium Special, with John Ussher on Diastolic Dysfunction, Norbert Stefan on MASLD, and Julia Critchley, Tess Harris, & Liza Bowen on Increased Risk of Infections in People Living with Diabetes

A Diabetes Symposium Special, with John Ussher on Diastolic Dysfunction, Norbert Stefan on MASLD, and Julia Critchley, Tess Harris, & Liza Bowen on Increased Risk of Infections in People Living with Diabetes

Welcome to the August 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darle...

7 Aug 1h 35min

Special Edition: Highlights from the ADA's 2026 Scientific Sessions

Special Edition: Highlights from the ADA's 2026 Scientific Sessions

In this special crossover episode, recorded live at the American Diabetes Association's Scientific Sessions in New Orleans, the hosts of the ADA's professional podcasts—DOC Updates, Diabetes Care "On ...

22 Jul 46min

Jennifer Thompson & Taylor Scheidl on Estrogen, Hyperplastic Adipose Expansion and Preserving Adipose Progenitor Cell Availability in Subcutaneous Depots of Female Mice, plus "Sweet Talk" with ghrelin hormone researcher Jeffrey Zigman

Jennifer Thompson & Taylor Scheidl on Estrogen, Hyperplastic Adipose Expansion and Preserving Adipose Progenitor Cell Availability in Subcutaneous Depots of Female Mice, plus "Sweet Talk" with ghrelin hormone researcher Jeffrey Zigman

Welcome to the July 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen...

9 Jul 1h 17min

T-Cell Memory and Metabolic Response to Weight Cycling, Gut-Derived FGF15 Modulating Lean Mass, Bone, and Bile Acid Responses to Weight Loss, plus "Sweet Talk" with Myers, past recipient of the Outstanding Scientific Achievement Award

T-Cell Memory and Metabolic Response to Weight Cycling, Gut-Derived FGF15 Modulating Lean Mass, Bone, and Bile Acid Responses to Weight Loss, plus "Sweet Talk" with Myers, past recipient of the Outstanding Scientific Achievement Award

Welcome to the June 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen...

12 Jun 1h 30min

Sushant Bhatnagar on Maintaining Glucose Homeostasis via Tomosyn-2, Vladimer Darsalia on insulin resistance and stroke outcomes, plus "Sweet Talk" with Timo Mueller, recipient of the 2026 Outstanding Scientific Achievement Award

Sushant Bhatnagar on Maintaining Glucose Homeostasis via Tomosyn-2, Vladimer Darsalia on insulin resistance and stroke outcomes, plus "Sweet Talk" with Timo Mueller, recipient of the 2026 Outstanding Scientific Achievement Award

Welcome to the May 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen ...

5 Mai 1h 20min

Fabriciova & Pavlinkova on Sex Differences in Diabetes Progression, Delgado-Corrales & Kim on Children with Islet Autoimmunity, plus "Sweet Talk" with Lora K. Heisler, recipient of the 2018 Outstanding Scientific Achievement Award.

Fabriciova & Pavlinkova on Sex Differences in Diabetes Progression, Delgado-Corrales & Kim on Children with Islet Autoimmunity, plus "Sweet Talk" with Lora K. Heisler, recipient of the 2018 Outstanding Scientific Achievement Award.

Welcome to the April 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darlee...

8 Apr 1h 35min

Matthew Merrins on Amino Acid Sensing, Noah Levi & Alejandro Caicedo on controlling pancreatic cell function through muscarinic receptor signaling, plus "Sweet Talk" about the upcoming Scientific Sessions with Mark Atkinson

Matthew Merrins on Amino Acid Sensing, Noah Levi & Alejandro Caicedo on controlling pancreatic cell function through muscarinic receptor signaling, plus "Sweet Talk" about the upcoming Scientific Sessions with Mark Atkinson

Welcome to the March 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darlee...

9 Mar 1h 17min

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