Oxygen in Fabric: The Passion and Grit Behind the Runway
SKIN DEEP20 Nov 2025

Oxygen in Fabric: The Passion and Grit Behind the Runway

If your career is your oxygen, how do you balance international manufacturing, teenage kids, and the tears that flow behind the Instagram-perfect moments?

Join Dr. Anna Chacon, board-certified dermatologist and host of Skin Deep, as she welcomes Ximena Kavalekas, the Ecuadorian-born fashion designer and creative force behind her eponymous luxury handbag brand. Known for blending Italian artistry with Miami sophistication, Kavalekas has built a successful fashion label specializing in exotic python and crocodile accessories crafted in Florence's most exclusive factories. But what does it really cost to breathe life into a dream? "This business is my oxygen," Kavalekas confesses. "I wouldn't be able to be without what I do." From studying at Polimoda in Florence to becoming the only Latin American designer with a flagship store in Miami's prestigious Design District—surrounded by Hermès, Dior, and billion-dollar brands—she shares the unfiltered reality behind the runway glamour.

This conversation goes beneath the surface of Instagram-perfect moments to reveal the tears, resilience, and courage required in fashion entrepreneurship. Kavalekas opens up about her failed first business during the 2011 recession, navigating complex customs regulations for exotic skins, and the dream every designer harbors: to one day sell to a major corporation like LVMH. How do you survive as a small luxury brand among corporate giants? What does it take to work with Italian factories that are "easier to get into Harvard than to get into"? From collaborating with Margherita Missoni to custom-designing crocodile doctor bags with 16 hand-matched skins, Kavalekas embodies the passion, mentorship, and hard-earned experience that defines lasting success in fashion.

In This Episode:

  • (00:00) Kavalekas reveals what it really takes to survive in luxury fashion
  • (04:45) Failed business, economic recession, and the courage to start over in 2015
  • (09:27) Navigating exotic skin customs regulations and Fish and Wildlife compliance
  • (12:32) Getting into Italy's exclusive factories: "easier to study at Harvard"
  • (18:37) Balancing international business, teenage kids, and family sacrifices
  • Share with a dermatology pro you know, like and subscribe to hear all of our future episodes!

About the show: Welcome to Skin Deep, a podcast designed for dermatology professionals. Host Dr. Anna Chacon, a distinguished dermatologist and author, shares her unique experiences and offers valuable insights on the future of dermatology, including telemedicine and teledermatology in reaching underserved communities. Dr. Chacon provides actionable recommendations for dermatology practices, emphasizing compassion, patient education, and staying current with advancements in the field.

About the host: Dr. Anna Chacon, board-certified dermatologist and founder of Indigenous Dermatology, specializes in treating patients in remote and rural communities. As the first dermatologist serving Alaska's Bush region, she travels by bush plane to reach isolated communities. Dr. Chacon holds medical licenses in all 50 states, DC, Guam, and the U.S. Virgin Islands, providing both in-person and teledermatology services.

Resources:
Website: https:...

Chapters
  • (00:00:00) - It takes a lot of courage to start a business
  • (00:00:16) - Meet Jimena Cavalecas
  • (00:03:16) - Ximena Cavalecas on Starting a Fashion Business
  • (00:09:10) - Exotics handbags: customs regulations in Italy
  • (00:11:09) - The Secret to Starting a Luxury Factory
  • (00:13:28) - The Dr. Crocodile Bag
  • (00:18:18) - How Do You Balance Your Business and Family?
  • (00:20:01) - Miami doctor and Missoni collaborator

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