664. Are Thousands of Medical Cures Hiding in Plain Sight?

664. Are Thousands of Medical Cures Hiding in Plain Sight?

Existing drugs can sometimes be repurposed to treat rare diseases. But making that match can be hard — and the financial incentives are weak. Guest host Steve Levitt tries to solve the puzzle.

  • SOURCES:
    • Chris Snyder, professor of economics at Dartmouth College.
    • David Fajgenbaum, co-founder and president of Every Cure, physician-scientist at the University of Pennsylvania.
    • Heather Stone, health science policy analyst at the Food & Drug Administration.
    • Sarrin Chethik, senior policy analyst at the Market Shaping Accelerator.


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Episoder(901)

666. This Is How Progress Happens

666. This Is How Progress Happens

Economists don’t usually talk about “culture.” But Joel Mokyr argues that it’s the engine of innovation — and the Nobel Prize committee agreed. Stephen Dubner sits down for a thousand-year conversatio...

6 Mar 53min

The Most Powerful People You’ve Never Heard Of (Update)

The Most Powerful People You’ve Never Heard Of (Update)

Just beneath the surface of the global economy, there is a hidden layer of dealmakers for whom war, chaos, and sanctions can be a great business opportunity. In this updated episode from 2025, journal...

4 Mar 1h 6min

665. Werner Herzog Isn’t Afraid ...

665. Werner Herzog Isn’t Afraid ...

... of bad reviews, meager financing, or artificial intelligence. But he is worried that the world is full of sloppy thinkers who mistake facts for the truth.   SOURCES: Werner Herzog, writer,...

27 Feb 49min

All You Need Is Nudge (Update)

All You Need Is Nudge (Update)

When Richard Thaler first published Nudge, the world was just starting to believe in his brand of behavioral economics. In this 2021 episode, we ask: How has nudge theory held up in the face of a glob...

18 Feb 57min

663. Is Weed a Performance-Enhancing Drug?

663. Is Weed a Performance-Enhancing Drug?

The science says no, at least not in the athletic sense. But the psychic benefits can be large — just ask former N.F.L. star Ricky Williams. He says athletes should consider cannabis a healing drug, n...

13 Feb 50min

662. If You’re Not Cheating, You’re Not Trying

662. If You’re Not Cheating, You’re Not Trying

In sports, the rules are meant to be sacrosanct. But when it comes to performance-enhancing drugs, the slope is super-slippery. (Part one of a two-part series.) SOURCES:April Henning, associate profes...

6 Feb 52min

Why Don’t Running Backs Get Paid Anymore? (Update)

Why Don’t Running Backs Get Paid Anymore? (Update)

They used to be the N.F.L.’s biggest stars, with paychecks to match. Now their salaries are near the bottom, and their careers are shorter than ever. In this updated episode from 2025, we speak with a...

4 Feb 58min

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