664. Are Thousands of Medical Cures Hiding in Plain Sight?

664. Are Thousands of Medical Cures Hiding in Plain Sight?

Existing drugs can sometimes be repurposed to treat rare diseases. But making that match can be hard — and the financial incentives are weak. Guest host Steve Levitt tries to solve the puzzle.

  • SOURCES:
    • Chris Snyder, professor of economics at Dartmouth College.
    • David Fajgenbaum, co-founder and president of Every Cure, physician-scientist at the University of Pennsylvania.
    • Heather Stone, health science policy analyst at the Food & Drug Administration.
    • Sarrin Chethik, senior policy analyst at the Market Shaping Accelerator.


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Episoder(902)

Why Don’t Running Backs Get Paid Anymore? (Update)

Why Don’t Running Backs Get Paid Anymore? (Update)

They used to be the N.F.L.’s biggest stars, with paychecks to match. Now their salaries are near the bottom, and their careers are shorter than ever. In this updated episode from 2025, we speak with a...

4 Feb 58min

661. Can A.I. Save Your Life?

661. Can A.I. Save Your Life?

For 50 years, the healthcare industry has been trying (and failing) to harness the power of artificial intelligence. It may finally be ready for prime time. What will this mean for human doctors — and...

30 Jan 1h

660. The Wellness Industry Is Gigantic — and Mostly Wrong

660. The Wellness Industry Is Gigantic — and Mostly Wrong

Zeke Emanuel (a physician, medical ethicist, and policy wonk) has some different ideas for how to lead a healthy and meaningful life. It starts with ice cream. (Part three of “The Freakonomics Radio G...

23 Jan 1h 5min

Steve Levitt Quits His Podcast, Joins Ours

Steve Levitt Quits His Podcast, Joins Ours

After five years, Levitt is ending People I (Mostly) Admire, and will start hosting the occasional Freakonomics Radio episode. We couldn’t be happier. SOURCES:Steve Levitt, co-author of Freakonomics a...

21 Jan 45min

659. Can Marty Makary Fix the F.D.A.?

659. Can Marty Makary Fix the F.D.A.?

It regulates 20 percent of the U.S. economy, and its commissioner has an aggressive agenda — faster drug approvals, healthier food, cures for diabetes and cancer. How much can he deliver? (Part two of...

16 Jan 55min

658. This Is Your Brain on Supplements

658. This Is Your Brain on Supplements

We all want to stay sharp, and forestall the cognitive effects of aging. But do brain supplements actually work? Are they safe? And why doesn’t the F.D.A. even know what’s in them? (Part one of “The F...

9 Jan 53min

Are Personal Finance Gurus Giving You Bad Advice? (Update)

Are Personal Finance Gurus Giving You Bad Advice? (Update)

One Yale economist certainly thinks so. But even if he’s right, are economists any better? We find out, in this update of a 2022 episode. SOURCES:James Choi, professor of finance at the Yale School of...

2 Jan 1h

Are You Ready for a Fresh Start? (Update)

Are You Ready for a Fresh Start? (Update)

Behavioral scientists have been exploring whether a psychological reset can lead to lasting change. In this update of a 2021 episode, we survey evidence from the London Underground, Major League Baseb...

30 Des 202542min

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