Fusion-negative Rhabdomyosarcoma: Clinical Application of Targeted RNA Sequencing

Fusion-negative Rhabdomyosarcoma: Clinical Application of Targeted RNA Sequencing

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Aida Glembocki, a Pediatric Pathologist and Masters Degree candidate at the University of Toronto, and Dr. Robert Siddaway, an Oncology Investigator at The Hospital for Sick Children in Toronto.

Hear about how The Hospital for Sick Children applies RNA sequencing in pediatric cancer diagnosis to reduce costs and identify key information for diagnostic classification. We also hear about their article in Pediatric and Developmental Pathology:

Fusion-Negative Rhabdomyosarcoma: Clinical Application of Targeted RNA Sequencing

Related article:

Siddaway R, Glembocki AI, Arnoldo A, Staunton J, Liu APY, Yuki KE, Yu M, Cohen-Gogo S, Shlien A, Villani A, Whitlock JA, Hitzler J, Tabori U, Levine AB, Lafrenière A, Nagy A, Chen H, Ngan BY, Somers GR, Abdelhaleem M, Chami R, Hawkins C. Clinical utility of targeted RNA sequencing in cancer molecular diagnostics. Nat Med. 2025 Oct;31(10):3524-3533. doi: 10.1038/s41591-025-03848-8. Epub 2025 Jul 17. PMID: 40676318.

Featured public domain music: Summer Pride by Loyalty Freak

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Episoder(24)

Perspectives 2026: Placenta Pathology

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In this special episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Bev Rogers of the University of Arizona and...

10 Jul 42min

Exploring the Impact and Prospects of Social Media in Advancing Pediatric Pathology

Exploring the Impact and Prospects of Social Media in Advancing Pediatric Pathology

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Sonja Chen (X: @IslandJewelsena, LinkedIn: Sonja Ch...

19 Jun 28min

Intervillous Thrombus Is Independently Associated With Placental Infarct and Single Umbilical Artery as well as Fetal Inflammatory Response

Intervillous Thrombus Is Independently Associated With Placental Infarct and Single Umbilical Artery as well as Fetal Inflammatory Response

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Peilin Zhang, a Pathologist at Sharp Memorial Hospi...

22 Mai 39min

Epididymal melanotic neuroectodermal tumor of infancy misdiagnosed as paratesticular rhabdomyosarcoma

Epididymal melanotic neuroectodermal tumor of infancy misdiagnosed as paratesticular rhabdomyosarcoma

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Manas Kalra, a Pediatric Oncologist in the Departme...

24 Apr 39min

A Novel GLCCI1::BRAF Fusion With Independent MYC and MYCN Amplifications in Pediatric Pancreatic Acinar Cell Carcinoma

A Novel GLCCI1::BRAF Fusion With Independent MYC and MYCN Amplifications in Pediatric Pancreatic Acinar Cell Carcinoma

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Lauren Miller (@LJMiller_MD), a 4th year AP/CP Path...

23 Jan 31min

Mediastinal NUT Carcinoma With Raised Serum Alpha-Fetoprotein Mimicking a Malignant Germ Cell Tumor: Suspicion Raised Due to Negative Serum miR-371a-3p Levels

Mediastinal NUT Carcinoma With Raised Serum Alpha-Fetoprotein Mimicking a Malignant Germ Cell Tumor: Suspicion Raised Due to Negative Serum miR-371a-3p Levels

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Professor Matthew J. Murray of the Department of Pathol...

12 Des 202552min

Indian Childhood Cirrhosis: Report of 2 Cases With Review of Literature and Implication of Metallothionein Immunohistochemical Expression

Indian Childhood Cirrhosis: Report of 2 Cases With Review of Literature and Implication of Metallothionein Immunohistochemical Expression

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Mukul Vij of the Department of Pathology, Dr. Rela ...

14 Nov 202545min

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