When RF Is Positive, But It’s Not RA
RheumRounds6 Aug 2025

When RF Is Positive, But It’s Not RA

🎙️ Episode 5 – When RF Is Positive, But It’s Not RA

“Doctor, my Rheumatoid Factor is positive — do I have RA?”


Not so fast.


In this episode of RheumRounds, Dr. Aravind Palraj unpacks the diagnostic and prognostic value of Rheumatoid Factor (RF) — and why a positive result often leads to confusion.


🧠 In just 7 minutes, you’ll learn:


  • What RF actually measures (and why it’s not specific)
  • Non-RA causes of RF positivity — from infections to Sjögren’s
  • How to interpret RF alongside anti-CCP and clinical signs



🎯 RF is a clue — not a verdict.

Learn to use it wisely, and stop overdiagnosing RA.


🎧 Host: Dr. Aravind Palraj

🎓 Senior Resident, Clinical Immunology & Rheumatology

📍 Madras Medical College, Chennai

📱 Follow on X: @Rheumat_Aravind

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Episoder(17)

Episode 17 — Autoinflammatory Diseases: Beyond Autoimmunity

Episode 17 — Autoinflammatory Diseases: Beyond Autoimmunity

🎙 Episode 17 — Autoinflammatory Diseases: Beyond AutoimmunityIn this in-depth episode of RheumRounds, Dr. Aravind Palraj unpacks the world of autoinflammatory diseases—conditions driven by the innate...

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Episode 16 – Vasculitis: An Introduction & Classification

Episode 16 – Vasculitis: An Introduction & Classification

🎙 Episode 16 — Vasculitis: When Blood Vessels Become TargetsIn this episode of RheumRounds, Dr. Aravind takes us through the fascinating and challenging world of vasculitis syndromes. What happens wh...

17 Aug 20259min

Episode 15— Scleroderma: Cracking the Code of a Complex Disease

Episode 15— Scleroderma: Cracking the Code of a Complex Disease

Episode 15 — Description:🩺 Scleroderma may start with cold fingers — but it’s much more than that. In this episode of RheumRounds, Dr. Aravind breaks down the types, symptoms, antibodies, and treatme...

15 Aug 20258min

Episode 14 – Pulmonary Hypertension in Connective Tissue Diseases: A Silent Threat

Episode 14 – Pulmonary Hypertension in Connective Tissue Diseases: A Silent Threat

🎙️ Episode 14 – Pulmonary Hypertension in Connective Tissue Diseases: A Silent Threat“Breathlessness in systemic sclerosis isn’t always lung fibrosis — sometimes it’s the right heart struggling.”In t...

14 Aug 20259min

🎙️ Episode 13 – “Macrophage Activation Syndrome: When Inflammation Turns Deadly”

🎙️ Episode 13 – “Macrophage Activation Syndrome: When Inflammation Turns Deadly”

🎙️ Episode 13 – Macrophage Activation Syndrome: When the Immune System Turns Deadly“In rheumatology, missing MAS by a few hours can cost a life.”In this episode of RheumRounds, Dr. Aravind Palraj bre...

13 Aug 20256min

Episode 12 – Scleroderma Renal Crisis: When Blood Pressure Is the Killer

Episode 12 – Scleroderma Renal Crisis: When Blood Pressure Is the Killer

🎙️ Episode 12 – Scleroderma Renal Crisis: When Blood Pressure Is the Killer“In systemic sclerosis, a sudden BP spike is never just hypertension.”In this episode of RheumRounds, Dr. Aravind Palraj exp...

12 Aug 20258min

Episode 11 – Pulmonary–Renal Syndrome: Treat First, Confirm Later

Episode 11 – Pulmonary–Renal Syndrome: Treat First, Confirm Later

🎙️ Episode 11 – Pulmonary–Renal Syndrome: Treat First, Confirm Later“Two failing organs. One urgent decision.”In this episode of RheumRounds, Dr. Aravind Palraj explains how to recognize and act fast...

11 Aug 20258min

🎙️ Episode 10 – Why Normal Creatinine Doesn’t Mean Normal Kidneys

🎙️ Episode 10 – Why Normal Creatinine Doesn’t Mean Normal Kidneys

🎙️ Episode 10 – Why Normal Creatinine Doesn’t Mean Normal Kidneys“The silent kidney damage you might be missing.”In this episode of RheumRounds, Dr. Aravind Palraj explains why creatinine can give a ...

10 Aug 20257min

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