This Week in Parasitism10 Nov 2016

TWiP 120: When they die they calcify

Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin

The TWiP triumvirate solve the case of the Thai Woman with Facial Swelling, and explain how Th17 T cells protect against the intracellular parasite Trypanosoma cruzi.

Become a patron of TWiP.

Links for this episode:

Th17 cells protect against Trypanosoma cruzi (PLoS Path)
Plasticity of helper CD4+ cells (Science)
Image credit
Letters read on TWiP 120

This episode is sponsored by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and nonfiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Case Study for TWiP 120

A 48 yo man from Mali comes to hospital ER in Washington Heights in NY with profuse watery diarrhea. Born in Mali, came to US at 18, working in US as long haul truck driver for 30 y, frequently visits Mali, recently to attend his father's funeral. Got symptoms one week after return (was there for 3 weeks). 3 liters diarrhea/day. No past med/surg history, not seen doctor in long time. No allergies. Unknown what father died of, Mother in Mali is ok. No medications. Some alcohol, marijuana use. Does report that has exposure to professional female sex workers, no condoms. Temp of 39 C, bp down 80/40, heart over 110, rapid breathing high 20s, cachectic. Wasted. Fungating lesion perianally. Undergoes HIV testing, clade B. T cells <100.

Send your case diagnosis, questions and comments to twip@microbe.tv

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(285)

TWiP 285: Why Is Cyclospora So Hard to Contain? Parasitologists Explain the 2026 US Outbreak

TWiP reviews our current understanding of the biology of Cyclospora, the parasite currently causing a large multistate outbreak in the US traced to contaminated lettuce, and why it is so difficult to ...

6 Aug 52min

TWiP 284: It's not the pork

TWiP solves the case of the 39-year-old man originally from Guatemala, who moved to one of the NYC boroughs in 2023 and presented with headaches for nearly 1 year. Hosts: Vincent Racaniello, Daniel Gr...

27 Jul 50min

TWiP 283: Warming up to cryptosporidiosis

TWiP reviews the projected impact of climate change on the burden of Cryptosporidium in Mali, Kenya, and The Gambia. Hosts: Vincent Racaniello and Christina Naula Subscribe (free): Apple Podcasts, Goo...

7 Jul 1h

TWiP 282: Does he live in New York?

TWiP solves the case of the nonbinary patient in his 30s with a history HIV/AIDS presenting with 3 weeks of subjective fevers, chills, generalized weakness and voluminous ostomy output. Hosts: Vincent...

24 Jun 53min

TWiP 281: Ants under the influence

TWiP reviews gene expression in wood ants infected with the larval lancet fluke, which causes them to leave their nest and attach to a flower until they are eaten by a grazing mammal. Hosts: Vincent R...

22 Jun 58min

TWiP 280: The wriggling diagnosis

TWiP solves the case of the 3 yo child, who recently immigrated to the US from Central America, in the ER with acute right lower quadrant abdominal pain and a rather active serpiginous wormlike 'thing...

29 Mai 57min

TWiP 279: Tolling for hookworms

TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S-transferase-1, an enzyme that performs a crucial enzymatic step in hookworm blood feeding. Hosts: Vin...

1 Mai 50min

TWiP 278: Trichinella from eating bear eyeballs

TWiP solves the case of the male in his 20s from Hokkaido, Japan, who developed fatigue and rash, followed by fever and myalgia 6 days later, after eating a raw bear eyeball. Hosts: Vincent Racaniello...

24 Apr 56min