234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Episoder(416)

242 | David Krakauer on Complexity, Agency, and Information

242 | David Krakauer on Complexity, Agency, and Information

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AMA | July 2023

AMA | July 2023

Welcome to the July 2023 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

3 Jul 20233h 4min

241 | Tim Maudlin on Locality, Hidden Variables, and Quantum Foundations

241 | Tim Maudlin on Locality, Hidden Variables, and Quantum Foundations

Last year's Nobel Prize for experimental tests of Bell's Theorem was the first Nobel in the foundations of quantum mechanics since Max Born in 1954. Quantum foundations is enjoying a bit of a resurgen...

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240 | Andrew Pontzen on Simulations and the Universe

240 | Andrew Pontzen on Simulations and the Universe

It's somewhat amazing that cosmology, the study of the universe as a whole, can make any progress at all. But it has, especially so in recent decades. Partly that's because nature has been kind to us ...

19 Jun 20231h 26min

239 | Brian Lowery on the Social Self

239 | Brian Lowery on the Social Self

There is an image, especially in Western cultures, of the rugged, authentic, self-made individual choosing how to navigate the intricacies of the social world. But there is no mystical soul within us,...

12 Jun 20231h 10min

AMA | June 2023

AMA | June 2023

Welcome to the June 2023 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

5 Jun 20232h 58min

238 | Scott Shapiro on the Technology and Philosophy of Hacking

238 | Scott Shapiro on the Technology and Philosophy of Hacking

Modern computers are somewhat more secure against being hacked - either by an inanimate virus or a human interloper - than they used to be. But as our lives are increasingly intertwined with computers...

29 Mai 20231h 27min

237 | Brooke Harrington on Offshore Wealth as a Complex System

237 | Brooke Harrington on Offshore Wealth as a Complex System

The modern world is large and interconnected, and there are a lot of systems that might be important to how it functions but about which most people are barely aware. One of these is the offshore weal...

22 Mai 20231h 18min

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